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The effect of the number of biopsies on the delay in the time from the delivery of mammography results to breast cancer histopathological diagnosis

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Abstract

Purpose

The delay in the time (in calendar days) from the delivery of mammography results to histopathological breast cancer (BC) diagnosis could be associated with more advanced clinical stages, a worse prognosis and higher mortality. Therefore, we assessed the association between the number of biopsies and the delay in the time (in calendar days) from the delivery of mammography results to histopathological BC.

Methods

A survey was performed on 563 women aged between 35 and 69 years with histopathologically confirmed BC who attended 11 Mexican hospitals.

Results

After adjusting for potential confounders, the odds of having a delay in the time (in calendar days) from the delivery of mammography results to histopathological BC diagnosis (≥ 60 days) among women with ≥ 3 biopsies were 2.99 times the odds of those who had only one biopsy (95% CI 1.35, 6.63).

Conclusion

The number of biopsies should be considered as a predictor of the time delay between the delivery of the mammography result and the diagnostic result.

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Data availability

The datasets generated during and/or analyzed during the current study are not publicly available but are available from the corresponding author on reasonable request.”

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Acknowledgments

We acknowledge the support of the recruitment sites, as well as the women participating in this research. We particularly thank María Felix Lazcano López, Libia Zulema Franco Velázquez, and Silvia Cardoso Muñoz for participating in the recruitment process.

Funding

This work was funded by Centro Nacional de Equidad de Género y Salud Reproductiva.

Author information

Authors and Affiliations

  1. School of Nursing and Obstetrics, Autonomous University of the State of Mexico, Paseo Tollocan s/n, Esquina Jesús Carranza, Col. Moderna de la Cruz, C.P. 50180, Toluca, MEX., Mexico

    Adriana Garduño-Alanis

  2. Research Department, Universidad de la Salud del Estado de México, Vialidad Toluca Atlacomulco 1946, Col. La Aviación, C.P. 50295, Toluca, MEX., Mexico

    Lizbeth Morales-González

  3. Center for Population Health Research, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico

    Angélica Ángeles-Llerenas & José Zaim Delgado-Ramírez

  4. School of Nursing and Nutrition, Autonomous University of San Luis Potosi, Av. Niño Artillero #130, Zona Universitaria, C.P. 78240, San Luis Potosí, Mexico

    Carolina Ortega-Olvera

  5. Center for Population Health Research, Instituto Nacional de Salud Pública, Mexico City, Mexico

    Gabriela Torres-Mejía

Authors
  1. Adriana Garduño-Alanis
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  5. Carolina Ortega-Olvera
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  6. Gabriela Torres-Mejía
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Contributions

AGA, AALL, and GTM contributed to the conception and design of the work; AGA and COO acquired the data; AGA, LMG, JZRD, and GTM contributed to the writing of the first draft of the manuscript; AGA, GTM, AALL, and COO contributed to the critical review of the manuscript; LMG and JZRD contributed to the review of the literature.

Corresponding author

Correspondence to Gabriela Torres-Mejía.

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The authors have no relevant financial or non-financial interests to disclose.

Ethical approval

This study was approved by the ethical research committee of the Institution.

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Informed consent was obtained from all individual participants included in the study.

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Garduño-Alanis, A., Morales-González, L., Ángeles-Llerenas, A. et al. The effect of the number of biopsies on the delay in the time from the delivery of mammography results to breast cancer histopathological diagnosis. Cancer Causes Control 33, 1355–1361 (2022). https://doi.org/10.1007/s10552-022-01622-6

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