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Shoulder amplitude movement does not influence postoperative wound complications after breast cancer surgery: a randomized clinical trial

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Abstract

Purpose

The goal of this study is to evaluate the influence of shoulder exercises with restricted amplitude movement (RAM) or free amplitude movement (FAM) performed from the first postoperative day (1st POD) on the incidence of surgical wound complications (SWC) in breast cancer.

Methods

This study comprises a randomized clinical trial with an intention-to-treat analysis including 465 women aged 18 to 79, who underwent curative surgery for breast cancer. Participants were submitted to perform free amplitude movement (FAM) or restricted amplitude movement (RAM) shoulder exercises, until the 30th postoperative day. The outcome measures were the SWC: seroma, dehiscence, necrosis, infection, hematoma and bruise.

Results

461 participants completed the follow-up. Thirty days after surgery, 63.8% of the women presented some surgical wound complication, with necrosis (39.3%) and seroma (30.8%) as the most frequent. No statistically significant differences in SWC according to postoperative amplitude shoulder exercise (FAM vs RAM), even after a stratified analysis by type of surgery (segmentectomy vs mastectomy) or axillary approach (axillary lymphadenectomy versus sentinel lymph node biopsy) were observed.

Conclusion

FAM exercises do not increase the incidence of postoperative wound complications compared to RAM exercises.

Trial registration: NCT03796845

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References

  1. Hoekstra HJ, Wobbes T, Heineman E, Haryono S, Aryandono T et al (2016) Fighting global disparities in cancer care: a surgical oncology view. Ann Surg Oncol 23(7):2131–2136. https://doi.org/10.1245/s10434-016-5194-3

    Article  Google Scholar 

  2. Macedo FO, Bergmann A, Koifman RJ, Torres DM, Costa RM, Silva IF (2018) Axillary surgery in breast cancer: acute postoperative complications in a hospital cohort of women of Rio de Janeiro Brazil. Mastology 28:80–86

    Article  Google Scholar 

  3. Glas De NA, Kiderlen M, Bastiaannet E, De Craen AJ, van de Water W, van de Velde CJ, Liefers GJ et al (2013) Postoperative complications and survival of elderly breast cancer patients: a FOCUS study analysis. Breast Cancer Res Treat;138(2):561–9. doi: 10.1007/s10549-013-2462-9.

  4. Stan D, Loprinzi CL, Ruddy KJ (2013) Breast cancer survivorship issues. Hematol Oncol Clin N Am 27(4):805–827. https://doi.org/10.1016/j.hoc.2013.05.005

    Article  Google Scholar 

  5. Ribeiro Pereira ACP, Koifman RJ, Bergmann A (2017) Incidence and risk factors of lymphedema after breast cancer treatment: 10 years of follow-up. Breast 36:67–73. https://doi.org/10.1016/j.breast.2017.09.006

    Article  Google Scholar 

  6. de Carvalho FN, Bergmann A, Koifman RJ (2014) Functionality in women with breast cancer: the use of international classification of functioning, disability and health (ICF) in clinical practice. J Phys Ther Sci 26(5):721–730. https://doi.org/10.1589/jpts.26.721

    Article  Google Scholar 

  7. Bergmann A, Mendes VV, Dias RA, Silva BA, Ferreira MGCL, Fabro EAN (2012) Incidence and risk factors for axillary web syndrome after breast cancer surgery. Breast Cancer Res Treat 131(3):987–992. https://doi.org/10.1007/s10549-011-1805-7

    Article  Google Scholar 

  8. Springer BA, Levy E, McGarvey C, Pfalzer LA, Stout NL, Gerber LH, Soballe PW, Danoff J (2010) Pre-operative assessment enables early diagnosis and recovery of shoulder function in patients with breast cancer. Breast Cancer Res Treat 120(1):135–147. https://doi.org/10.1007/s10549-009-0710-9

    Article  Google Scholar 

  9. Zomkowski K, de Souza BC, da Silva FP, Moreira GM, de Cunha N, Sperandio FF (2018) Physical symptoms and working performance in female breast cancer survivors: a systematic review. Disabil Rehabil 40(13):1485–1493. https://doi.org/10.1080/09638288.2017.1300950

    Article  Google Scholar 

  10. Baima J, Reynolds SG, Edmiston K, Larkin A, Ward BM, O'Connor A (2017) Teaching of independent exercises for prehabilitation in breast cancer. J Cancer Educ 32(2):252–256. https://doi.org/10.1007/s13187-015-0940-y

    Article  Google Scholar 

  11. de Oliveira MM, de Rezende LF, de Amaral MT, Silva MP, Morais SS, Gurgel MS (2014) Manual lymphatic drainage versus exercise in the early postoperative period for breast cancer. Physiother Theory Pract 30(6):384–389. https://doi.org/10.3109/09593985.2013.876695

    Article  Google Scholar 

  12. Testa A, Iannace C, Di Libero L (2014) Strengths of early physical rehabilitation programs in surgical breast cancer patients: results of a randomized controlled study. Eur J Phys Rehabil Med 50(3):275–284

    CAS  Google Scholar 

  13. Rezende LF, Beletti PO, Franco RL, Moraes SS, Gurgel MSC (2006) Exercícios livres versus direcionados nas complicações pós-operatórias de câncer de mama. Rev Assoc Med Bras 52(1):37–42

    Article  Google Scholar 

  14. Silva MPP, Derchain FM, Rezende L, Cabello C, Martinez EZ (2004) Movimento do ombro após cirurgia por carcinoma invasor da mama: estudo randomizado prospectivo controlado de exercícios livres versus limitados a 90º no pós-operatorio. Rev Bras Ginecol Obstet 26:125–130

    Article  Google Scholar 

  15. Shamley DR, Barker K, Simonite V, Beardshaw A (2005) Delayed versus immediate exercises following surgery for breast cancer: a systematic review. Breast Cancer Res Treat 90(3):263–271

    Article  Google Scholar 

  16. De Groef A, Van Kampen M, Dieltjens E, Christiaens MR, Neven P, Geraerts I, Devoogdt N (2015) Effectiveness of postoperative physical therapy for upper-limb impairments after breast cancer treatment: a systematic review. Arch Phys Med Rehabil 96(6):1140–1153. https://doi.org/10.1016/j.apmr.2015.01.006

    Article  Google Scholar 

  17. McNeely ML, Campbell K, Ospina M, Rowe BH, Dabbs K, Klassen TP, Mackey J, Courneya K (2010) Exercise interventions for upper-limb dysfunction due to breast cancer treatment. Cochrane Database Syst Rev 6:CD005211. https://doi.org/10.1002/14651858.CD005211.pub2

    Article  Google Scholar 

  18. Cinar N, Seckin U, Keskin D, Bodur H, Bozkurt B, Cengiz O (2008) The effectiveness of early rehabilitation in patients with modified radical mastectomy. Cancer Nurs 31(2):160–165. https://doi.org/10.1097/01.NCC.0000305696

    Article  Google Scholar 

  19. Gozzo TO, Almeida AM, Panobianco MS, Brito LGO, Carrara HHA (2008) Estudo comparativo da eficácia da movimentacão precoce do braço no controle do seroma pos-linfadenectomia axilar em mulheres com câncer de mama. Rev Bras de Mastologia 18:58–62

    Google Scholar 

  20. Sampathraju S, Rodrigues G (2010) Seroma formation after mastectomy: pathogenesis and prevention. Indian J Surg Oncol 1(4):328–333. https://doi.org/10.1007/s13193-011-0067-5

    Article  Google Scholar 

  21. Harris SR, Schmitz KH, Campbell KL, McNeely ML (2012) Clinical practice guidelines for breast cancer rehabilitation: syntheses of guideline recommendations and qualitative appraisals. Cancer 118(8 Suppl):2312–2324. https://doi.org/10.1002/cncr.27461

    Article  Google Scholar 

  22. Tood J, Scally A, Dodwell D, Horgan K, Topping AN (2008) A randomised controlled trial of two programmes of shoulder exercise following axillary node dissection for invasive breast cancer. Physiotherapy 94(4):265–273

    Article  Google Scholar 

  23. Petito EL, Esteves MT, Elias S, Facina G, Nazário AC, Gutiérrez MG (2014) The influence of the initiation of an exercise programme on seroma formation and dehiscence following breast cancer surgery. J Clin Nurs 23(21–22):3087–3094. https://doi.org/10.1111/jocn.12544

    Article  Google Scholar 

  24. Lauridsen MC, Christiansen P, Hessov I (2005) The effect of physiotherapy on shoulder function in patients surgically treated for breast cancer: a randomized study. Acta Oncol 44(5):449–457

    Article  Google Scholar 

  25. Ganz PA (2008) Psychological and social aspects of breast cancer. Oncology (Williston Park) 22(6):642–646

    Google Scholar 

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Authors and Affiliations

  1. Clinical Research Division, Brazilian National Cancer Institute, Rio de Janeiro, Brazil

    Clarice Gomes Chagas Teodózio, Liz de Oliveira Marchito, Suzana Sales de Aguiar, Luiz Claudio Santos Thuler & Anke Bergmann

  2. Physiotherapy Department, Brazilian National Cancer Institute, Rio de Janeiro, Brazil

    Erica Alves Nogueira Fabro & Flávia Oliveira Macedo

  3. Clinical Research Coordination, Brazilian National Cancer Institute, Rua André Cavalcanti, 37 - Anexo - 3o andar - Centro, CEP 20231-050, Rio de Janeiro, Brazil

    Anke Bergmann

Authors
  1. Clarice Gomes Chagas Teodózio
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  2. Liz de Oliveira Marchito
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  3. Erica Alves Nogueira Fabro
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  4. Flávia Oliveira Macedo
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  5. Suzana Sales de Aguiar
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  6. Luiz Claudio Santos Thuler
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  7. Anke Bergmann
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Corresponding author

Correspondence to Anke Bergmann.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The study protocol was approved by the Brazilian National Cancer Institute (INCA) Research Ethics Committee.

Informed consent

All patients were informed of the study protocol and signed an informed consent form before assessment.

Research involving human and animal participants

This article does not contain any studies with animals performed by any of the authors.

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Teodózio, C.G.C., Marchito, L.d.O., Fabro, E.A.N. et al. Shoulder amplitude movement does not influence postoperative wound complications after breast cancer surgery: a randomized clinical trial. Breast Cancer Res Treat 184, 97–105 (2020). https://doi.org/10.1007/s10549-020-05826-9

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  • DOI: https://doi.org/10.1007/s10549-020-05826-9

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