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Biomimetic soft micro-swimmers: from actuation mechanisms to applications

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Abstract

Underwater robot designs inspired by the behavior and morphological characteristics of aquatic animals can provide reinforced mobility and energy efficiency. In the past two decades, the emerging materials science and integrated circuit technology have been combined and applied to various types of bionic soft underwater miniaturized robots by researchers around the world. Further, the potential applications of biomimetic soft micro-swimmers in the biological and medical fields have been explored. Here, this paper reviews the development of biomimetic soft tiny swimmers, which are designed based on a variety of intelligent materials and control strategies. This review focuses on the various actuation mechanisms of soft tiny swimmers reported in the past two decades and classifies these robots into four categories: fish-like, snake-like, jellyfish-like and microbial-inspired ones. Besides, this review considers the practical challenges faced by actuation mechanisms of each type of robot, and summarizes and prospects how these challenges affect the potential applications of robots in real environments.

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References

  • M. Aureli, V. Kopman, M. Porfiri, IEEE/ASME Trans. Mechatron. 15(4), 603–614 (2010)

    Article  Google Scholar 

  • E. Avci, M. Grammatikopoulou, G.-Z. Yang, Adv. Opt. Mater. 5(19), 6 (2017)

    Google Scholar 

  • I.Z. Awan, A.Q. Khan, J. Chem. Soc. Pak. 40(1), 1–23 (2018)

    Google Scholar 

  • P.R. Bandyopadhyay, IEEE J. Ocean. Eng. 30(1), 109–139 (2005)

    Article  Google Scholar 

  • P.R. Bandyopadhyay, D.N. Beal, A. Menozzi, J. Exp. Biol. 211(2), 206–214 (2008)

    Article  Google Scholar 

  • G.J. Berg, M.K. McBride, C. Wang, C.N. Bowman, Polymer 55(23), 5849–5872 (2014)

    Article  Google Scholar 

  • P. Brochu, Q. Pei, Macromol. Rapid Commun. 31(1), 10–36 (2010)

    Article  Google Scholar 

  • D.R. Brumley, R. Rusconi, K. Son, R. Stocker, Eur. Phys. J. Spec. Top. 224(17–18), 3119–3140 (2015)

    Article  Google Scholar 

  • H. Ceylan, I.C. Yasa, O. Yasa, A.F. Tabak, J. Giltinan, M. Sitti, ACS Nano 13(3), 3353–3362 (2019)

    Article  Google Scholar 

  • Z. Chen, S. Shatara, X. Tan, IEEE/ASME Trans. Mechatron. 15(3), 448–459 (2010)

    Article  Google Scholar 

  • X.Z. Chen, M. Hoop, F. Mushtaq, E. Siringil, C.Z. Hu, B.J. Nelson, S. Pane, Appl. Mater. Today 9, 37–46 (2017)

    Article  Google Scholar 

  • Y. Chen, H. Zhao, J. Mao, P. Chirarattananon, E.F. Helbling, N.-S.P. Hyun, D.R. Clarke, R.J. Wood, Nat. 575(7782), 324−+ (2019)

    Article  Google Scholar 

  • C. Christianson, N.N. Goldberg, D.D. Deheyn, S. Cai, M.T. Tolley, Sci. Robot. 3(17), 8 (2018)

    Article  Google Scholar 

  • W.S. Chu, K.T. Lee, S.H. Song, M.W. Han, J.Y. Lee, H.S. Kim, M.S. Kim, Y.J. Park, K.J. Cho, S.H. Ahn, Int. J. Precis. Eng. Manuf. 13(7), 1281–1292 (2012)

    Article  Google Scholar 

  • S.E. Chung, X. Dong, M. Sitti, Lab Chip 15(7), 1667–1676 (2015)

    Article  Google Scholar 

  • G. Cicconofri, A. DeSimone, Comput Fluids 179, 799–805 (2019)

  • S.P. Colin, J.H. Costello, J. Exp. Biol. 205(3), 427–437 (2002)

    Article  Google Scholar 

  • W. Coral, C. Rossi, O.M. Curet, D. Castro, Bioinspir. Biomim. 13(5), 056009 (2018)

    Article  Google Scholar 

  • A. Crespi, A.J. Ijspeert, IEEE Trans. Robot. 24(1), 75–87 (2008)

    Article  Google Scholar 

  • P. Dario, M.C. Carrozza, E. Guglielmelli, C. Laschi, A. Menciassi, S. Micera, F. Vecchi, IEEE Robot. Autom. Mag. 12(2), 29–45 (2005)

    Article  Google Scholar 

  • E. Diller, J. Giltinan, G.Z. Lum, Z. Ye, M. Sitti, Int. J. Robot. Res. 35(1–3), 114–128 (2016)

    Article  Google Scholar 

  • Y. Ding, F. Qiu, X.C.I. Solvas, F.W.Y. Chiu, B.J. Nelson, A. deMello, Micromachines 7(2), 13 (2016)

    Article  Google Scholar 

  • S. Floyd, E. Diller, C. Pawashe, M. Sitti, Int. J. Robot. Res. 30(13), 1553–1565 (2011)

    Article  Google Scholar 

  • X. Fu, F. Li, W.T. Liu, C. Stefanini, P. Dario, Lect. Notes. Artif. Intell. 6424, 477–487 (2010)

    Google Scholar 

  • H.C. Fu, M. Jabbarzadeh, F. Meshkati, Phys. Rev. E 91(4), 13 (2015)

    Article  Google Scholar 

  • A. Ghosh, P. Fischer, Nano Lett. 9(6), 2243–2245 (2009)

    Article  Google Scholar 

  • H. Godaba, J.S. Li, Y.Z. Wang, J. Zhu, IEEE Robotics. Autom. Lett. 1(2), 624–631 (2016)

    Article  Google Scholar 

  • C. Graf, J. Hitzbleck, T. Feller, K. Clauberg, J. Wagner, J. Krause, J. Maas, J. Intell. Mater. Syst. Struct. 25(8), 951–966 (2014)

    Article  Google Scholar 

  • G.Y. Gu, J. Zhu, L.M. Zhu, X.Y. Zhu, Bioinspir. Biomim. 12(1), 22 (2017)

    Article  Google Scholar 

  • M. Hagiwara, T. Kawahara, Y. Yamanishi, F. Arai, Adv. Robot. 25(8), 991–1005 (2011)

    Article  Google Scholar 

  • J.K. Hamilton, A.D. Gilbert, P.G. Petrov, F.Y. Ogrin, Phys. Fluids 30(9), 8 (2018)

    Article  Google Scholar 

  • S. Hirose, H. Yamada, IEEE Robot. Autom. Mag. 16(1), 88–98 (2009)

    Article  Google Scholar 

  • W.Q. Hu, K.S. Ishii, A.T. Ohta, Appl. Phys. Lett. 99(9), 3 (2011)

    Google Scholar 

  • W. Hu, G.Z. Lum, M. Mastrangeli, M. Sitti, Nature 554(7690), 81–85 (2018)

    Article  Google Scholar 

  • H. Huang, G. Yan, X. Xiong, Electric Machines and Control 6(3), 249–251 (2002)

    Google Scholar 

  • C. Huang, J.-a. Lv, X. Tian, Y. Wang, Y. Yu, J. Liu, Sci. Rep. 5, 8 (2015)

    Google Scholar 

  • H.W. Huang, M.S. Sakar, A.J. Petruska, S. Pane, B.J. Nelson, Nat. Commun. 7, 12263 (2016)

    Article  Google Scholar 

  • E.E. Hunter, E.W. Brink, E.B. Steager, V. Kumar, IEEE Robotics. Autom. Lett. 3(3), 1592–1599 (2018)

    Article  Google Scholar 

  • V. Iacovacci, G. Lucarini, C. Innocenti, N. Comisso, P. Dario, L. Ricotti, A. Menciassi, Biomed. Microdevices 17(6), 7 (2015)

    Article  Google Scholar 

  • M. Ikeda, S. Hikasa, K. Watanabe, I. Nagai, Artif. Life. Robotics 19(2), 136–141 (2014)

    Article  Google Scholar 

  • J.M. Jani, M. Leary, A. Subic, M.A. Gibson, Mater. Des. 56, 1078–1113 (2014)

    Article  Google Scholar 

  • B.C. Jayne, A.F. Bennett, Evolution 44(5), 1204–1229 (1990)

    Article  Google Scholar 

  • H. Jin, E. Dong, G. Alici, S. Mao, X. Min, C. Liu, K.H. Low, J. Yang, Bioinspir. Biomim. 11(5), 056012 (2016)

    Article  Google Scholar 

  • C. Jo, D. Pugal, I.-K. Oh, K.J. Kim, K. Asaka, Prog. Polym. Sci. 38(7), 1037–1066 (2013)

    Article  Google Scholar 

  • N. Kamamichi, M. Yamakita, K. Asaka, Z.W. Luo, IEEE, in IEEE International Conference on Robotics and Automation (ICRA) (IEEE, New York, 2006), pp. 1812–1817

  • M. A. Kazemi-Laria, A. D. Dostine, J. Zhang, A. S. Wineman, J. A. Shaw, in Bioinspiration, Biomimetics, and Bioreplication IX (SPIE, State of Washington, 2019), 1906504. https://doi.org/10.1117/12.2513456

  • I.S.M. Khalil, H.C. Dijkslag, L. Abelmann, S. Misra. Appl. Phys. Lett. 104(22) (2014)

  • I.S.M. Khalil, A.F. Tabak, Y. Hamed, M. Tawakol, A. Klingner, N.E. Gohary, B. Mizaikoff, M. Sitti, IEEE Robotics. Autom. Lett. 3(3), 1703–1710 (2018a)

    Article  Google Scholar 

  • I.S.M. Khalil, A.F. Tabak, Y. Hamed, M.E. Mitwally, M. Tawakol, A. Klingner, M. Sitti, Adv. Sci. 5(2), 1700461 (2018b)

    Article  Google Scholar 

  • S. Kim, S. Lee, J. Lee, B.J. Nelson, L. Zhang, H. Choi, Sci. Rep. 6, 30713 (2016)

    Article  Google Scholar 

  • H.S. Kim, J.Y. Lee, W.S. Chu, S.H. Ahn, Soft Rob. 4(1), 49–60 (2017)

    Article  Google Scholar 

  • E. Lauga, T.R. Powers, Rep. Prog. Phys. 72(9), 096601 (2009)

    Article  Google Scholar 

  • B.T. Lester, T. Baxevanis, Y. Chemisky, D.C. Lagoudas, Acta Mech. 226(12), 3907–3960 (2015)

    Article  Google Scholar 

  • T.F. Li, G.R. Li, Y.M. Liang, T.Y. Cheng, J. Dai, X.X. Yang, B.Y. Liu, Z.D. Zeng, Z.L. Huang, Y.W. Luo, T. Xie, W. Yang, Sci. Adv. 3(4), 7 (2017)

    Article  Google Scholar 

  • J. Li, X. Li, T. Luo, R. Wang, C. Liu, S. Chen, D. Li, J. Yue, S.-H. Cheng, D. Sun, Sci. Robot. 3(19), 11 (2018)

    Article  Google Scholar 

  • P. Liao, L. Xing, S. Zhang, D. Sun, Small 15(36), e1901197 (2019)

    Article  Google Scholar 

  • P. Liljeback, K.Y. Pettersen, O. Stavdahl, J.T. Gravdahl, Robot. Auton. Syst. 60(1), 29–40 (2012)

    Article  Google Scholar 

  • Y.J. Liu, X.W. Sun, Y. Li, J.B. Liu, Adv. Mater. Res. 591-593, 381–384 (2012)

    Article  Google Scholar 

  • G.Z. Lum, Z. Ye, X. Dong, H. Marvi, O. Erin, W. Hu, M. Sitti, Proc. Natl. Acad. Sci. U. S. A. 113(41), E6007–E6015 (2016)

    Article  Google Scholar 

  • M. Luo, Y. Feng, T. Wang, J. Guan, Adv. Funct. Mater. 28(25), 23 (2018)

    Article  Google Scholar 

  • V. Magdanz, S. Sanchez, O.G. Schmidt, Adv. Mater. 25(45), 6581–6588 (2013)

    Article  Google Scholar 

  • S.X. Mao, E.B. Dong, H. Jin, M. Xu, S.W. Zhang, J. Yang, K.H. Low, J. Bionic Eng. 11(3), 400–411 (2014)

    Article  Google Scholar 

  • C. McClure, M.C. Quist, J.R. Kozfkay, M.P. Peterson, D.J. Schill, N. Am. J. Fish Manag. 40(1), 154–162 (2020)

    Article  Google Scholar 

  • A.G. Ming, T. Ichikawa, W.J. Zhao, M. Shimojo, IEEE, in 2014 IEEE International Conference on Robotics and Biomimetics (ROBIO) (IEEE, New York, 2014), pp. 761–766

  • S. Nakamura, Biomolecules 10(4), 16 (2020)

    Article  Google Scholar 

  • J.C. Nawroth, H. Lee, A.W. Feinberg, C.M. Ripplinger, M.L. McCain, A. Grosberg, J.O. Dabiri, K.K. Parker, Nat. Biotechnol. 30(8), 792–797 (2012)

    Article  Google Scholar 

  • Y. Ogawa, D. Ando, Y. Sutou, J. Koike, Science 353(6297), 368–370 (2016)

    Article  Google Scholar 

  • S. Palagi, A.G. Mark, S.Y. Reigh, K. Melde, T. Qiu, H. Zeng, C. Parmeggiani, D. Martella, A. Sanchez-Castillo, N. Kapernaum, F. Giesselmann, D.S. Wiersma, E. Lauga, P. Fischer, Nat. Mater. 15(6), 647−+ (2016)

    Article  Google Scholar 

  • A. Poulin, C.S. Demir, S. Rosset, T.V. Petrova, H. Shea, Lab Chip 16(19), 3788–3794 (2016)

    Article  Google Scholar 

  • F. Qiu, S. Fujita, R. Mhanna, L. Zhang, B.R. Simona, B.J. Nelson, Adv. Funct. Mater. 25(11), 1666–1671 (2015)

    Article  Google Scholar 

  • Y. Qiu, E. Zhang, R. Plamthottam, Q.B. Pei, Acc. Chem. Res. 52(2), 316–325 (2019)

    Article  Google Scholar 

  • M.M. Rahman, Y. Toda, H. Miki, J. Bionic Eng. 8(1), 25–32 (2011)

    Article  Google Scholar 

  • A. Raj, A. Thakur, Bioinspir. Biomim. 11(3), 23 (2016)

    Article  Google Scholar 

  • Z. Ren, W. Hu, X. Dong, M. Sitti, Nat. Commun. 10(1), 2703 (2019)

    Article  Google Scholar 

  • M. Saito, M. Fukaya, T. Iwasaki, IEEE Control. Syst. Mag. 22(1), 64–81 (2002)

    Article  Google Scholar 

  • S. Sanchez, L. Soler, J. Katuri, Angew. Chem. Int. Ed. 54(5), 1414–1444 (2015)

    Article  Google Scholar 

  • L. Seminara, L. Pinna, M. Valle, L. Basirico, A. Loi, P. Cosseddu, A. Bonfiglio, A. Ascia, M. Biso, A. Ansaldo, D. Ricci, G. Metta, IEEE Sensors J. 13(10), 4022–4029 (2013)

    Article  Google Scholar 

  • M. Sfakiotakis, D.M. Lane, J.B.C. Davies, IEEE J. Ocean. Eng. 24(2), 237–252 (1999)

    Article  Google Scholar 

  • L. Shi, S. Guo, K. Asaka, Int. J. Robot. Autom. 26(2), 229–241 (2011)

    Google Scholar 

  • S. Shian, R.M. Diebold, D.R. Clarke, Opt. Express 21(7), 8669–8676 (2013)

    Article  Google Scholar 

  • S.R. Shin, B. Migliori, B. Miccoli, Y.C. Li, P. Mostafalu, J. Seo, S. Mandla, A. Enrico, S. Antona, R. Sabarish, T. Zheng, L. Pirrami, K. Zhang, Y.S. Zhang, K.T. Wan, D. Demarchi, M.R. Dokmeci, A. Khademhosseini, Adv. Mater. 30(10), 13 (2018)

    Article  Google Scholar 

  • J. Shintake, B. Schubert, S. Rosset, H. Shea, D. Floreano, IEEEin 2015 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) (IEEE, New York, 2015), pp. 1097–1102. https://doi.org/10.1109/IROS.2015.7353507

  • J. Shintake, H. Shea, D. Floreano, IEEE,  in 2016 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) (IEEE, New York, 2016), pp. 4957–4962

  • J. Shintake, V. Cacucciolo, H. Shea, D. Floreano, Soft Rob. 5(4), 466–474 (2018)

    Article  Google Scholar 

  • M. Su, T.T. Xu, J. Liu, L. Manamanchaiyaporn, Y.M. Guan, Z.M. Hao, X.Y. Wu, IEEE, in International Conference on Control Automation Robotics and Vision (IEEE, New York, 2018), pp. 113–118

  • B. A. Trimmer, H. T. Lin, A. Baryshyan, G. G. Leisk, D. L. Kaplan, in 2012 4th IEEE RAS & EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob) (IEEE, New York, 2012), pp. 599–605. https://doi.org/10.1109/BioRob.2012.6290698

  • F. Ullrich, C. Bergeles, J. Pokki, O. Ergeneman, S. Erni, G. Chatzipirpiridis, S. Pane, C. Framme, B.J. Nelson, Invest. Ophthalmol. Vis. Sci. 54(4), 2853–2863 (2013)

    Article  Google Scholar 

  • M.J. Villangca, D. Palima, A.R. Banas, J. Gluckstad, Light-Sci. Appl. 5, 7 (2016)

    Article  Google Scholar 

  • A. Villanueva, C. Smith, S. Priya, Bioinspir. Biomim. 6(3), 036004 (2011)

    Article  Google Scholar 

  • Z. Wang, G. Hang, J. Li, Y. Wang, K. Xiao, Sensors Actuators A Phys. 144(2), 354–360 (2008)

    Article  Google Scholar 

  • D.B. Wang, H.W. Liang, H. Zhu, S. Zhang, Sensors 14(7), 13006–13023 (2014)

    Article  Google Scholar 

  • D. Wang, Y. Hu, P.F. Liu, D. Luo, Acc. Chem. Res. 50(4), 733–739 (2017)

    Article  Google Scholar 

  • X.X. Wang, W.Z. Song, M.H. You, J. Zhang, M. Yu, Z.Y. Fan, S. Ramakrishna, Y.Z. Long, ACS Nano 12(8), 8588–8596 (2018)

    Article  Google Scholar 

  • S. Wang, B. Huang, D. McCoul, M. Li, L. Mu, J. Zhao, Smart Mater. Struct. 28(4), 9 (2019)

    Google Scholar 

  • B.J. Williams, S.V. Anand, J. Rajagopalan, M.T. Saif, Nat. Commun. 5, 3081 (2014)

    Article  Google Scholar 

  • P.S. Xiao, N.B. Yi, T.F. Zhang, Y. Huang, H.C. Chang, Y. Yang, Y. Zhou, Y.S. Chen, Adv. Sci. 3(6), 1500438 (2016)

    Article  Google Scholar 

  • N.W. Xu, J.O. Dabiri, Sci. Adv. 6(5) (2020)

  • T. Xu, J. Zhang, M. Salehizadeh, O. Onaizah, E. Diller, Sci. Robot. 4(29), 12 (2019)

    Article  Google Scholar 

  • Y. Yalikun, K. Uesugi, M. Hiroki, Y. Shen, Y. Tanaka, Y. Akiyama, K. Morishima, Actuators 8(2), 15 (2019)

    Article  Google Scholar 

  • Y. Yang, M. Zhang, D. Li, Y. Shen, Adv. Mater. Technol. 4(1), 6 (2019)

  • Z. Ye, S. Regnier, M. Sitti, IEEE Trans. Robot. 30(1), 3–13 (2014)

  • J.Z. Yu, M. Tan, S. Wang, E. Chen, IEEE Trans. Syst. Man Cybern. B Cybern. 34(4), 1798–1810 (2004)

    Article  Google Scholar 

  • J. Yu, X. Li, L. Pang, Z. Wu, Sci. Chin. Inf. Sci. 62(9), 3 (2019)

    Article  Google Scholar 

  • H. Zeng, P. Wasylczyk, C. Parmeggiani, D. Martella, M. Burresi, D.S. Wiersma, Adv. Mater. 27(26), 3883−+ (2015)

    Article  Google Scholar 

  • Y. Zhang, J. He, K.H. Low, J. Bionic Eng. 9(2), 166–176 (2012)

    Article  Google Scholar 

Download references

Acknowledgements

The authors would like to thank the financial support from the National Science Foundation of China (No.61803088), the Natural Science Foundation of Fujian Province, China (No. 2017 J01748), the Open Project Programs from both the State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences (Grant No: 2017-O02) and Fuzhou University Testing Fund of precious apparatus (No. 2019 T015 and No. 2020 T016).

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Fu, S., Wei, F., Yin, C. et al. Biomimetic soft micro-swimmers: from actuation mechanisms to applications. Biomed Microdevices 23, 6 (2021). https://doi.org/10.1007/s10544-021-00546-3

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