A mathematical model of the systemic circulation is described. The model takes into consideration the baroreceptor and humoral regulation of the heart rate and provides simulation of changes in the main hemodynamic parameters under various physiological conditions.
Similar content being viewed by others
References
Itkin, G. P., Development and Testing of Control Systems for Heart Prostheses Using Mathematical Modeling [in Russian], Candidate’s Dissertation, Moscow (1974).
Solodyannikov, Yu. V., Elements of Mathematical Modeling and Identification of Blood Circulation [in Russian], Samara (1994), pp. 5–15.
Proshin, A. P. and Solodyannikov, Yu. V., “Mathematical modeling of the circulatory system and its practical application,” Avtom. Telemekh., 2, 174–188 (2006).
Rushmer, R. F., “Cardiovascular dynamics,” Acad. Med., 36, No. 6, 742 (1961).
Ferrari, G., De Lazzari, C., Mimmo, R., Tosti, G., and Ambrosi, D., “A modular numerical model of the cardiovascular system for studying and training in the field of cardiovascular physiopathology,” J. Biomed. Eng., 14, No. 2, 91–107 (1992).
Gohean, J. R., George, M. J., Pate, T. D., Kurusz, M., Longoria, R. G., and Smalling, R. W., “Verification of a computational cardiovascular system model comparing the hemodynamics of a continuous flow to a synchronous valveless pulsatile flow left ventricular assist device,” ASAIO J., 59, No. 2, 107 (2013).
Karvonen, J. and Vuorimaa, T., “Heart rate and exercise intensity during sports activities,” Sports Med., 5, No. 5, 303–311 (1988).
Miyai, N., Arita, M., Miyashita, K., Morioka, I., Shiraishi, T., and Nishio, I., “Blood pressure response to heart rate during exercise test and risk of future hypertension,” Hypertension, 39, No. 3, 761–766 (2002).
Donald, D. E. and Shepherd, J. T., “Initial cardiovascular adjustment to exercise in dogs with chronic cardiac denervation,” Am. J. Physiology-Legacy Content, 207, No. 6, 1325–1329 (1964).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Meditsinskaya Tekhnika, Vol. 55, No. 4, Jul.-Aug., 2021, pp. 41-44.
Rights and permissions
About this article
Cite this article
Syrbu, A.I., Itkin, G.P., Kuleshov, A.P. et al. A Mathematical Model of Neurohumoral Regulation of the Circulatory System. Biomed Eng 55, 284–288 (2021). https://doi.org/10.1007/s10527-021-10119-6
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10527-021-10119-6