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Regeneration of Articular Cartilage in Experimental Osteoarthrosis after Injection of a Complex Polyacrylamide-Hyaluronic Gel

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Biomedical Engineering Aims and scope

The regenerative capacity of articular cartilage was assessed after injection of Matricin polyacrylamide-hyaluronic gel into the knee joints of nine rabbits with a model of osteoarthrosis. Matricin decreased dystrophic and destructive changes in articular cartilage previously induced by exposure to papain solution and produced a significant increase in the regenerative capacity of the damaged hyaline cartilage.

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Authors and Affiliations

  1. M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia

    V. V. Zar

  2. Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Moscow, Russia

    A. B. Shekhter & M. V. Zar

  3. Moscow Regional Hospital for War Veterans, Zhilino, Moscow Region, Russia

    E. N. Sukhanov

Authors
  1. V. V. Zar
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  2. A. B. Shekhter
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  3. E. N. Sukhanov
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  4. M. V. Zar
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Correspondence to V. V. Zar.

Additional information

Translated from Meditsinskaya Tekhnika, Vol. 53, No. 4, Jul.-Aug., 2019, pp. 14-16.

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Zar, V.V., Shekhter, A.B., Sukhanov, E.N. et al. Regeneration of Articular Cartilage in Experimental Osteoarthrosis after Injection of a Complex Polyacrylamide-Hyaluronic Gel. Biomed Eng 53, 244–248 (2019). https://doi.org/10.1007/s10527-019-09918-9

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  • DOI: https://doi.org/10.1007/s10527-019-09918-9

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