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The Role of Carbon Monoxide in the Reactions of Arterial Branches of the Uterine Artery of Rats to Low-Intensity Irradiation with a Helium-Neon Laser

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Bulletin of Experimental Biology and Medicine Aims and scope

Biomicroscopy was used to study order I-IV branches of the uterine artery in sexually mature female Wistar rats after a single 5- or 10-min direct exposure of the right broad ligament of the uterus to a helium-neon laser beam in the red band of the spectrum (λ=632.8 nm, output power 2 mW, intensity 20 mW/cm2). Under the influence of laser exposure, there was a significant increase in the diameter of small uterine branches and a weaker increase in large vessels with a well-developed muscular membrane. Preliminary administration of zinc IX protoporphyrin hemoxygenase blocker (30 mmol/kg) reduced reactivity of the vascular bed to laser irradiation, mainly of order I-II branches. It was concluded that carbon monoxide can act as an intermediary between the laser exposure and uterine vessels.

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Authors and Affiliations

  1. Department of Human Anatomy, Pacific State Medical University, Ministry of Health of the Russian Federation, Vladivostok, Russia

    V. M. Chertok & A. E. Kotsyuba

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  1. V. M. Chertok
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  2. A. E. Kotsyuba
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Correspondence to V. M. Chertok.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 173, No. 6, pp. 779-782, June, 2022

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Chertok, V.M., Kotsyuba, A.E. The Role of Carbon Monoxide in the Reactions of Arterial Branches of the Uterine Artery of Rats to Low-Intensity Irradiation with a Helium-Neon Laser. Bull Exp Biol Med 173, 787–789 (2022). https://doi.org/10.1007/s10517-022-05632-x

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  • DOI: https://doi.org/10.1007/s10517-022-05632-x

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