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Structural Analysis of Peripheral Organs of the Immune System in the Assessment of Grippol Vaccine Safety

  • IMMUNOLOGY AND MICROBIOLOGY
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Bulletin of Experimental Biology and Medicine Aims and scope

The safety of Grippol vaccine was assessed by macro- and microscopic methods in the experiment. The morphological features of group lymphoid nodules of the small intestine were studied on days 4, 7, 14 and 30 after vaccination. The structural morphological dynamics of lymphoid tissue under these conditions is shown. Because of the use of the vaccine, the lymphocytopoietic processes in the body are activated, which indicates the formation of an immune response.

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Authors and Affiliations

  1. I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia

    S. V. Klochkova, A. A. Bakhmet, D. A. Sheptulin & D. B. Nikityuk

  2. Federal Research Center for Nutrition, Biotechnology and Food Safety, Moscow, Russia

    D. B. Nikityuk

Authors
  1. S. V. Klochkova
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  2. A. A. Bakhmet
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  3. D. A. Sheptulin
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  4. D. B. Nikityuk
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Corresponding author

Correspondence to S. V. Klochkova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 167, No. 2, pp. 209-212, February, 2019

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Klochkova, S.V., Bakhmet, A.A., Sheptulin, D.A. et al. Structural Analysis of Peripheral Organs of the Immune System in the Assessment of Grippol Vaccine Safety. Bull Exp Biol Med 167, 255–258 (2019). https://doi.org/10.1007/s10517-019-04503-2

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  • DOI: https://doi.org/10.1007/s10517-019-04503-2

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