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Association of Regulatory and Adaptive Status in Humans with Serotonergic Transmitter System Gene Polymorphism

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Bulletin of Experimental Biology and Medicine Aims and scope

The regulatory and adaptive status was determined in 202 healthy subjects by the parameters of the cardiorespiratory synchronism probe. We performed molecular-genetic analysis of polymorphic variants of the main gene of serotonin biosynthesis, tryptophan hydroxylase TPH1 (A218C polymorphism) and TPH2 (G703T polymorphism), and serotonin receptors (HTR2C and HTR2A genes). The association of the regulatory and adaptive status of a subject with the polymorphism of serotonergic mediator system genes was revealed.

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Authors and Affiliations

  1. Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia

    V. M. Pokrovskii, Yu. V. Kashina, O. V. Kiek, V. G. Abushkevich, A. G. Penzhoyan & N. V. Zabolotskikh

  2. Center for Molecular Genetic Studies, Department of Genetics, Bashkir State Pedagogical University, Ufa, Republic of Bashkortostan, Russia

    O. V. Gumerova & V. Yu. Gorbunova

Authors
  1. V. M. Pokrovskii
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  2. Yu. V. Kashina
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  3. O. V. Kiek
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  4. O. V. Gumerova
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  5. V. Yu. Gorbunova
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  6. V. G. Abushkevich
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  7. A. G. Penzhoyan
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  8. N. V. Zabolotskikh
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Corresponding author

Correspondence to V. M. Pokrovskii.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 166, No. 10, pp. 482-484, October, 2018

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Pokrovskii, V.M., Kashina, Y.V., Kiek, O.V. et al. Association of Regulatory and Adaptive Status in Humans with Serotonergic Transmitter System Gene Polymorphism. Bull Exp Biol Med 166, 487–488 (2019). https://doi.org/10.1007/s10517-019-04378-3

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  • DOI: https://doi.org/10.1007/s10517-019-04378-3

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