We studied the effects of human platelet-rich plasma and platelet lysate on proliferation, migration, and colony-forming properties of rat mesenchymal stem cells. Platelet-rich plasma and platelet lysate stimulated the proliferation, migration, and colony formation of mesenchymal stem cells. A real-time study showed that platelet-rich plasma produces the most potent stimulatory effect, while both platelet-rich plasma and platelet lysate stimulated migration of cells.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 163, No. 6, pp. 722-725, June, 2017
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Lykov, A.P., Bondarenko, N.A., Surovtseva, M.A. et al. Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells. Bull Exp Biol Med 163, 757–760 (2017). https://doi.org/10.1007/s10517-017-3897-5
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DOI: https://doi.org/10.1007/s10517-017-3897-5