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Magnetic Resonance Imaging of Tumors with the Use of Iron Oxide Magnetic Nanoparticles as a Contrast Agent

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Bulletin of Experimental Biology and Medicine Aims and scope

We studied the possibility of using BSA-coated magnetic iron oxide nanoparticles for magnetic resonance imaging diagnosis of C6 glioblastoma, 4T1 mammary adenocarcinoma, and RS-1 hepatic mucous carcinoma. In all three cases, magnetic nanoparticles accumulated in the tumor and its large vessels. Magnetic resonance imaging with contrast agent allows visualization of the tumor tissue and its vascularization.

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Authors and Affiliations

  1. N. I. Pirogov Russian National Research Medical University, Moscow, Russia

    A. S. Semkina, M. A. Abakumov & V. P. Chekhonin

  2. MISiS National Research Technological University, Moscow, Russia

    M. A. Abakumov

  3. V. P. Serbsky Federal Medical Center of Psychiatry and Narcology, Ministry of Health of the Russian Federation, Moscow, Russia

    N. F. Grinenko, N. V. Nukolova & V. P. Chekhonin

  4. N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation, Moscow, Russia

    A. A. Lipengolts

  5. MIFI National Research Nuclear University, Moscow, Russia

    A. A. Lipengolts

Authors
  1. A. S. Semkina
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  2. M. A. Abakumov
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  3. N. F. Grinenko
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  4. A. A. Lipengolts
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  5. N. V. Nukolova
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  6. V. P. Chekhonin
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Corresponding author

Correspondence to A. S. Semkina.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 12, pp. 781-785, December, 2016

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Semkina, A.S., Abakumov, M.A., Grinenko, N.F. et al. Magnetic Resonance Imaging of Tumors with the Use of Iron Oxide Magnetic Nanoparticles as a Contrast Agent. Bull Exp Biol Med 162, 808–811 (2017). https://doi.org/10.1007/s10517-017-3718-x

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  • DOI: https://doi.org/10.1007/s10517-017-3718-x

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