We examined 11 women aged 19-26 years (mean age 22.5±3.5 years) with secondary amenorrhea complaining frequent urination over 1.5 years and repeatedly, but unsuccessful treated for overactive bladder and chronic cystitis. The rare cause of sustained urination disorders in young female patients of reproductive age was established: development of secondary amenorrhea caused by weight loss (“cosmetic” amenorrhea) with subsequent estrogene deficit and urogenital atrophy. Morphological examination of the bladder mucosa, an important clue to the diagnosis, helps to identify the true cause of dysuria, urogenital atrophy of the bladder mucosa, in secondary (“cosmetic”) amenorrhea, and determine future course of etiopathogenic treatment of sustained dysuria in young women. The treatment is often effective in case of proper and timely diagnosis and the absence of irreversible changes.
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Manukhin IB, Gevorkyan MA, Tumilovich LG, Kushlinskii NE. Amenorrhea Akush., Ginekol., Reproductol. 2009;(3):35-38. Russian.
Teterina TA, Apolikhina IA. Modern opportunities for therapy of chronic cystitis and resistant overactive bladder in women. Effekt. Farmakoter. 2014;(54): 42-47. Russian.
Flores-Carreras O, Martínez-Espinoza CJ, González-Ruiz MI, Montes-Casillas YE. Contribution of bladder biopsy to the study of urogynaecological patient. Ginecol. Obstet. Mex. 2010;78(3):187-190.
Nakamura Y, Yoshimura Y, Oda T, Kamei K, Iizuka R. Amenorrhea due to weight loss. Nihon Sanka Fujinka Gakkai Zasshi. 1984;36(5):727-735.
Neymeyer J, Miller K. Urogynaecology for urologists. Aktuelle Urol. 2011;42(4):233-241.
Parsons CL. The role of a leaky epithelium and potassium in the generation of bladder symptoms in interstitial cystitis/overactive bladder, urethral syndrome, prostatitis and gynaecological chronic pelvic pain. BJU Int. 2011;107(3):370-375.
Practice Committee of American Society for Reproductive Medicine. Current evaluation of amenorrhea. Fertil. Steril. 2008;90(5, Suppl):S219-S225.
Wakeling A. Epidemiology of anorexia nervosa. Psychiatry Res. 1996;62(1):3-9.
Wallace KM, Drake MJ. Overactive bladder. F1000Res. 2015;4. pii: F1000 Faculty Rev-1406. doi: 10.12688/f1000research.7131.1.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 161, No. 8, pp. 152-156, August, 2016
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Shelkovnikova, N.V., Neimark, A.I., Taranina, T.S. et al. Pathogenic Features of Dysuria in Young Women with Secondary Amenorrhea Caused by Body Weight Loss. Bull Exp Biol Med 162, 191–194 (2016). https://doi.org/10.1007/s10517-016-3573-1
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DOI: https://doi.org/10.1007/s10517-016-3573-1