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Immune Homeostasis of Human Gastric Mucosa in Helicobacter pylori Infection

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Bulletin of Experimental Biology and Medicine Aims and scope

We present the results of electron microscopic, microbiological, immunohistochemical, and molecular genetic studies of gastric biopsy specimens taken for diagnostic purposes according by clinical indications during examination of patients with gastrointestinal pathology. Immune homeostasis of the gastric mucosa against the background of infection with various pathogen strains of Helicobacter pylori was studied in patients of different age groups with peptic ulcer, gastritis, metaplasia, and cancer. Some peculiarities of Helicobacter pylori contamination in the gastric mucosa were demonstrated. Immune homeostasis of the gastric mucosa in different pathologies was analyzed depending on the Helicobacter pylori genotype.

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Authors and Affiliations

  1. Engineering School, Far Eastern Federal University, Vladivostok, Russia

    I. V. Reva & G. V. Reva

  2. School of Biomedicine, Far Eastern Federal University, Vladivostok, Russia

    S. S. Vershinina & G. V. Reva

  3. International Medical Research Center (IMERC), Niigata, Japan

    T. Yamamoto

Authors
  1. I. V. Reva
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  2. T. Yamamoto
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  3. S. S. Vershinina
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  4. G. V. Reva
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Correspondence to G. V. Reva.

Additional information

Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 1, pp. 44-51, January, 2015

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Reva, I.V., Yamamoto, T., Vershinina, S.S. et al. Immune Homeostasis of Human Gastric Mucosa in Helicobacter pylori Infection. Bull Exp Biol Med 159, 157–163 (2015). https://doi.org/10.1007/s10517-015-2913-x

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  • DOI: https://doi.org/10.1007/s10517-015-2913-x

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