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Stress-Protective Effect of Thymic Peptides

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Experiments on Wistar rats showed that thymic peptides produce a stress-protective effect that manifested in prevention of functional impairment of conditioned active avoidance response and a decrease in generalized motor activity typical of higher nervous activity failure. We concluded that thymic peptides significantly modulate integrative functions of the brain and produce a stress-protective effect.

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Authors and Affiliations

  1. Department of Higher Nervous Activity, Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia

    A. V. Novoseletskaya & A. N. Inozemtsev

  2. Department of Pharmacology, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia

    N. M. Kiseleva

  3. Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physical-Chemical Medicine, Federal Medical and Biological Agency, Moscow, Russia

    I. V. Zimina, O. V. Belova, V. Ya. Arion & V. I. Sergienko

Authors
  1. A. V. Novoseletskaya
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  2. N. M. Kiseleva
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  3. I. V. Zimina
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  4. O. V. Belova
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  5. A. N. Inozemtsev
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  6. V. Ya. Arion
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  7. V. I. Sergienko
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Corresponding author

Correspondence to A. V. Novoseletskaya.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 158, No. 12, pp. 715-718, December, 2014

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Novoseletskaya, A.V., Kiseleva, N.M., Zimina, I.V. et al. Stress-Protective Effect of Thymic Peptides. Bull Exp Biol Med 158, 753–755 (2015). https://doi.org/10.1007/s10517-015-2854-4

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  • DOI: https://doi.org/10.1007/s10517-015-2854-4

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