This article contains an exposition of a quasi-biological model of radiation carcinogenesis. The model was developed to describe the dependence of the radiogenic cancer incidence rate on the age at single exposure to radiation and the age at follow-up. The mathematical image of the model is compared with the corresponding ICRP and UNSCEAR mathematical models. The model is used to analyze the latest data on the cancer incidence rate in a cohort of Japanese people (2009) exposed to radiation from atomic explosions in 1945. It is shown to have methodological possibilities and advantages. The model parameters of radiogenic and background cancer incidence rates in the LSS cohort are given.
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References
A. T. Gubin and V. A. Sakovich, “Evolution of models for taking into account non-uniform exposure in time in radiogenic risk assessments,” At. Energ., 129, No. 6, 340–346 (2020).
ICRP Publication 103 [Russian translation], PKF Alana, Moscow (2009).
Effects of Ionizing Radiation. Annex A: Epidemiological Studies of Radiation and Cancer, UNSCEAR 2006 Report to the General Assembly with Scientific Annexes, New York (2008).
L. A. Gavrilov and N. S. Gabrilova, The Biology of Longevity, Nauka, Moscow (1991), 2nd ed.
D. Preston, E. Ron, and S. Tokuoka, “Solid cancer incidence in atomic bomb survivors: 1958–1998,” Rad. Res., 168, 1–64 (2007).
Health Risks from Exposure to Low Levels of Ionizing Radiation: BEIR VII Phase 2, Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation, Washington (2006).
V. A. Sakovich, A. T. Gubin, M. V. Gogoleva, and V. I. Redko, “Load model of radiation risk and its modifications,” Probl. Anal. Riska, 1, No. 1, 76–98 (2004).
Electronic Resource Radiation Effects Research Foundation, file sol_col_2017exp_v1.csv, acc. Oct. 25, 2017.
Electronic Resource Radiation Effects Research Foundation, file lccinc07.csv, acc. Oct. 25, 2017.
A. T. Gubin, “Method for global fitting of generalized radiogenic risk models to Japanese cohort data,” Rad. Gigiena, No. 11(3), 56–73 (2018).
E. J. Grant, A. Brenner, and Sugiyama Hiromi, “Solid cancer incidence among the life span study of atomic bomb survivors: 1958–2009,” Radiat. Res., 187, 513–537 (2017).
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Translated from Atomnaya Énergiya, Vol. 132, No. 1, pp. 34–42, January, 2022.
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Sakovich, V.A., Gubin, A.T. & Red’ko, V.I. Estimated Parameters for Models of Radiation Risk With Irregular Radiation Exposure Times According to LSS Cohort Data. At Energy 132, 37–44 (2022). https://doi.org/10.1007/s10512-022-00901-4
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DOI: https://doi.org/10.1007/s10512-022-00901-4