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Heterosexual Cisgender Men Partnered with Transgender Women Exhibit Higher HIV/STI Sexual Risk than Their Gay, Bisexual, and Queer Counterparts: Findings from a U.S.-Based Convenience Sample Recruited Online

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Abstract

Cisgender men are frequently vectors for HIV transmission among transgender women. Despite this, the correlates of sexual risk among these men remain under-examined. The purpose of the present study was to explore potential differences in relationship characteristics, sexual risk-taking, and risk-reduction strategies among cisgender men partnered with transgender women. The study utilized secondary screening data provided by adult cis men who reported being in a primary relationship with a trans woman (N = 710). Gay men (18%) were comparatively older, and most likely to report both HIV seropositivity and committed pairings. Heterosexual men (14%) were more likely to report exchange sex, briefer relationships, extra-dyadic sex, lesser serostatus awareness or PrEP uptake. Queer men (7%) were youngest, and most likely to access PrEP. Heterosexual cis men with trans women partners may be subject to unique socio-cultural drivers of sexual risk, such as heteronormative pressures and relationship stigma.

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Acknowledgements

The authors would like to thank Scott Jones and Hannah Park for their contributions to this study.

Funding

Data collection was supported by Grants from the National Institute of Allergy and Infectious Diseases, National Institute on Mental Health, Eunice Kennedy Shriver National Institute on Child Health and Human Development, and National Institute on Drug Abuse (UG3AI133674, PI: Rendina; R01MH114735, PI: Rendina; R01DA041262, PI: Starks; R34DA043422, PI: Starks; R01DA045613, PI: Starks; U19HD089875, PI: Naar).

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Simone J. Skeen and Dr. Demetria Cain conceived the study, executed the analysis, interpreted the results, and led the writing of the introduction, methods, results and discussion section. Dr. Tyrel J. Starks and Dr. H. Jonathon Rendina contributed to the formulation of the study, analysis and interpretation of results, and the crafting of all sections of the manuscript. Ruben H. Jimenez contributed to participant recruitment, data collection, and the crafting of the methods and results sections.

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Correspondence to Simone J. Skeen.

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Skeen, S.J., Starks, T.J., Jimenez, R.H. et al. Heterosexual Cisgender Men Partnered with Transgender Women Exhibit Higher HIV/STI Sexual Risk than Their Gay, Bisexual, and Queer Counterparts: Findings from a U.S.-Based Convenience Sample Recruited Online. AIDS Behav 25, 3279–3291 (2021). https://doi.org/10.1007/s10461-021-03314-9

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