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A Latent Class Analysis of HIV Risk Factors Among Men and Women with Opioid Use Disorder in Pre-trial Detention

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Abstract

Adults entering pre-trial detention who inject drugs are at high risk for acquiring HIV/AIDS. In the current study, we examined pre-incarceration HIV risk behaviors among 114 people with opioid use disorder who inject drugs. Participants were recruited from the Baltimore City Detention Center as part of a randomized controlled trial of pre-release methadone treatment. Using latent class analysis, we found three separate latent classes, which we identified as the sex exchange class (14.2%), drug equipment sharing class (36.8%) and lower risk class (49.0%). Women in the sex exchange class (n = 16) reported having multiple male partners and selling sex for money or drugs; however, this group also reported more consistent condom use and less frequent injection drug and equipment sharing than participants in the drug equipment sharing class. Our findings highlight distinct profiles of jail detainees with OUD based on their risks for HIV, and could inform more targeted interventions for each group.

Clinical Trials Registration: Clinicaltrials.gov NCT 02334215

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Funding

This work was supported by National Institute on Drug Abuse (NIDA) (Grant No. 2 U01 DA01363) and the Laura and John Arnold Foundation. NIDA or the National Institutes of Health had no role in the design and conduct of the study; data acquisition, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript. The content is solely the responsibility of the authors and does not necessarily represent the official views of NIDA or the National Institutes of Health.

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  1. Friends Research Institute, 1040 Park Ave, Suite 103, Baltimore, MD, 21201, USA

    Mary M. Mitchell, Jan Gryczynski, Shannon G. Mitchell, Sharon M. Kelly, Kevin E. O’Grady, Laura B. Monico & Robert P. Schwartz

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  1. Mary M. Mitchell
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Dr. Schwartz reports providing consultation to Verily Life Sciences. No financial disclosures were reported by the other authors.

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Mitchell, M.M., Gryczynski, J., Mitchell, S.G. et al. A Latent Class Analysis of HIV Risk Factors Among Men and Women with Opioid Use Disorder in Pre-trial Detention. AIDS Behav 24, 1776–1783 (2020). https://doi.org/10.1007/s10461-019-02726-y

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