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Factors Associated with Improved HIV/AIDS Treatment Outcomes: Comparing two Major ART Service Delivery Models in Vietnam

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Abstract

A mixed design approach was performed to assess the CD4 count levels over time and their associated factors among 362 HIV patients on ART from clinics with HIV testing and counseling (ART-HTC) services and those with general healthcare (ART-GH) services. Longitudinal CD4 count data were retrospectively collected from medical records. Sociodemographic, clinical, alcohol use and smoking characteristics were obtained via face-to-face interviews. Multivariate mixed effect linear regression was utilized to determine the association. We found that HIV patients at ART-GH clinics were more likely to achieve higher CD4 counts over time compared to patients at ART-HTC clinics. Additionally, having an increase in CD4 counts was found to be associated with having longer duration of ART and higher baseline CD4 levels. Cigarette smoking and hazardous alcohol use, however, were not associated with CD4 count improvement. Our findings suggest that combining HTC and GH services might provide a synergistic benefit in ART treatment outcomes through an improved access to comprehensive HIV healthcare services for HIV patients on therapy.

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Acknowledgements

We would like to thank the participants and staffs at the participating clinics.

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Authors and Affiliations

  1. Institute for Preventive Medicine and Public Health, Hanoi Medical University, 1 Ton That Tung, Kim Lien, Dong Da, Hanoi, Vietnam

    Bach Xuan Tran

  2. Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA

    Bach Xuan Tran & Carl A. Latkin

  3. Université Claude Bernard Lyon 1, 69100, Villeurbanne, France

    Quang Nhat Nguyen

  4. Institute for Global Health Innovations, Duy Tan University, Da Nang, 550000, Vietnam

    Quang Nhat Nguyen & Cuong Tat Nguyen

  5. Center of Excellence in Behavioral Medicine, Nguyen Tat Thanh University, Ho Chi Minh city, Vietnam

    Long Hoang Nguyen & Nu Thi Truong

  6. Center of Excellence in Health Services and System Research, Nguyen Tat Thanh University, Ho Chi Minh city, Vietnam

    Huyen Phuc Do

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Correspondence to Bach Xuan Tran.

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Tran, B.X., Nguyen, Q.N., Nguyen, L.H. et al. Factors Associated with Improved HIV/AIDS Treatment Outcomes: Comparing two Major ART Service Delivery Models in Vietnam. AIDS Behav 23, 2840–2848 (2019). https://doi.org/10.1007/s10461-019-02571-z

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