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Emerging Trends in Heart Valve Engineering: Part II. Novel and Standard Technologies for Aortic Valve Replacement

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Abstract

The engineering of technologies for heart valve replacement (i.e., heart valve engineering) is an exciting and evolving field. Since the first valve replacement, technology has progressed by leaps and bounds. Innovations emerge frequently and supply patients and physicians with new, increasingly efficacious and less invasive treatment options. As much as any other field in medicine the treatment of heart valve disease has experienced a renaissance in the last 10 years. Here we review the currently available technologies and future options in the surgical and transcatheter treatment of aortic valve disease. Different valves from major manufacturers are described in details with their applications.

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Acknowledgments

This review article was prepared after the Mathematics Guiding Bioartificial Heart Valve Design meeting held at the Ohio State University, October 28 to 31, 2013. The authors would like to acknowledge the Mathematical Biosciences Institute and its grant from National Science Foundation (DMS 0931642) that facilitated the meeting.

Conflict of interest

Arash Kheradvar is a co-founder of FOLDA LLC, the manufacturer of FOLDAVALVE. Otherwise the remaining authors have nothing to disclose.

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Authors and Affiliations

  1. Department of Biomedical Engineering, The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, 2410 Engineering Hall, Irvine, CA, 92697-2730, USA

    Arash Kheradvar, Elliott M. Groves, S. Hamed Alavi & Ahmad Falahatpisheh

  2. Department of Internal Medicine, Division of Cardiology, University of California, Irvine School of Medicine, Irvine, CA, USA

    Arash Kheradvar & Elliott M. Groves

  3. Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA

    Craig J. Goergen

  4. Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA

    Robert Tranquillo

  5. Department of Mechanical & Industrial Engineering, University of Toronto, Toronto, ON, Canada

    Craig A. Simmons

  6. Institute of Biomaterials & Biomedical Engineering, University of Toronto, Toronto, ON, Canada

    Craig A. Simmons

  7. Department of Mechanical Engineering, School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA

    Lakshmi P. Dasi

  8. Department of Bioengineering, Rice University, Houston, TX, USA

    K. Jane Grande-Allen

  9. Department of Bioengineering and Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA

    Mohammad R. K. Mofrad

  10. Department of Mathematics, Center for Interdisciplinary Applied Mathematics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

    Boyce Griffith

  11. McAllister Heart Institute, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA

    Boyce Griffith

  12. Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands

    Frank Baaijens

  13. Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA

    Stephen H. Little

  14. Department of Mathematics, University of Houston, Houston, TX, USA

    Suncica Canic

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  1. Arash Kheradvar
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  2. Elliott M. Groves
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  10. Ahmad Falahatpisheh
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Correspondence to Arash Kheradvar.

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Associate Editor Estefanía Peña oversaw the review of this article.

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Kheradvar, A., Groves, E.M., Goergen, C.J. et al. Emerging Trends in Heart Valve Engineering: Part II. Novel and Standard Technologies for Aortic Valve Replacement. Ann Biomed Eng 43, 844–857 (2015). https://doi.org/10.1007/s10439-014-1191-5

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  • DOI: https://doi.org/10.1007/s10439-014-1191-5

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