Abstract
Cardiac hemangiomas are rare benign tumors. Here, we report the case of a man in his 30s who had a cardiac hemangioma with no symptoms. He was being treated with β-blockers for chronic heart failure with hypertensive heart disease at Osaka Minato Central Hospital. Routine echocardiography revealed a mobile spherical mass in the left ventricle that had not been detected on echocardiography performed 4 months previously. Subsequently, the tumor was excised to prevent potential embolic events and was pathologically diagnosed as a cardiac hemangioma. This case demonstrates the relatively rapid progress of a cardiac hemangioma regardless of β-blocker administration, which is occasionally used for the treatment of hemangiomas. The efficacy of β-blockers in treating cardiac hemangiomas may vary according to the type of β-blocker. Echocardiography is useful in screening and follow-up of cardiac hemangiomas; however, additional imaging modalities are needed for differential diagnosis.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Reynen K. Frequency of primary tumors of the heart. Am J Cardiol. 1996;77:107.
Burke A, Virmani R. Tumors of the heart and great vessels. In: Atlas of the tumor pathology, 3rd series, Fascicle 16. Washington, DC: Armed Forces Institute of Pathology; 1996. pp. 1–98.
Patel SD, Peterson A, Bartczak A, et al. Primary cardiac angiosarcoma—a review. Med Sci Monit. 2014;20:103–9.
Li W, Teng P, Xu H, et al. Cardiac hemangioma: a comprehensive analysis of 200 cases. Ann Thorac Surg. 2015;99:2246–52.
Palmer TE, Tresch DD, Bonchek LI. Spontaneous resolution of a large, cavernous hemangioma of the heart. Am J Cardiol. 1986;58:184–5.
Chalet Y, Mace L, Franc B, et al. Angiosarcoma 7 years after surgical excision of histiocytoid haemangioma in left atrium. Lancet. 1993;341:1217.
Tomizawa Y, Endo M, Nishida H, et al. Reconstruction of the left ventricle in a patient with cardiac hemangioma at the apex. Ann Thorac Surg. 2001;71:2032–4.
Di Valentino M, Menafoglio A, Mazzucchelli L, et al. A rapid-growing left intraventricular cardiac hemangioma. J Am Soc Echocardiogr. 2006;19:e5–7.
Tal R, Dotan M, Lorber A, et al. Approach to haemangiomatosis causing congestive heart failure. Acta Paediatr. 2016;105:600–4.
Wu S, Wang B, Chen L, et al. Clinical efficacy of propranolol in the treatment of hemangioma and changes in serum VEGF, bFGF and MMP-9. Exp Ther Med. 2015;10:1079–83.
Izumiya Y, Shiojima I, Sato K, et al. Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload. Hypertension. 2006;47:887–93.
Leaute-Labreze C, Dumas de la Roque E, Hubiche T, et al. Propranolol for severe hemangiomas of infancy. N Engl J Med. 2008;358:2649–51.
Velthuis BO, van Es J, van Houwelingen G, et al. Extensive left ventricular hemangioma. J Am Coll Cardiol. 2012;60:e35.
Boer RA, Siebelink HM, Tio RA, et al. Carvedilol increases plasma vascular endothelial growth factor (VEGF) in patients with chronic heart failure. Eur J Heart Fail. 2001;3:331–3.
Papadopoulos K, Makrides CA, Eleutheriou E, et al. A cardiac haemangioma: the contribution of myocardial contrast echocardiography in the diagnosis. BMJ Case Rep. 2015;2015.
Nomeir AM, Watts LE, Seagle R, et al. Intracardiac myxomas: twenty-year echocardiographic experience with review of the literature. J Am Soc Echocardiogr. 1989;2:139–50.
McAllister HA Jr. Primary tumors and cysts of the heart and pericardium. Curr Probl Cardiol. 1979;4:1–51.
Elbardissi AW, Dearani JA, Daly RC, et al. Survival after resection of primary cardiac tumors: a 48-year experience. Circulation. 2008;118:S7–15.
Alsaileek A, Tepe SM, Alveraz L, et al. Diagnostic features of cardiac hemangioma on cardiovascular magnetic resonance: a case report. Int J Cardiovasc Imaging. 2006;22:699–702.
Fang L, He L, Chen Y, et al. Infiltrating lipoma of the right ventricle involving the interventricular septum and tricuspid valve: report of a rare case and literature review. Medicine. 2016;95:e2561.
Hrabak-Paar M, Hubner M, Stern-Padovan R, et al. Hemangioma of the interatrial septum: CT and MRI features. Cardiovasc Interv Radiol. 2011;34:S90–3.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no competing interests.
Ethical statement
All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. Written informed consent was obtained from the patient.
Electronic supplementary material
Below is the link to the electronic supplementary material.
The round and high echoic mass pedunculated at the basal interventricular septum with remarkable mobility
About this article
Cite this article
Yamamoto, H., Beppu, S. Left ventricular cardiac hemangioma in a patient with chronic heart failure. J Med Ultrasonics 45, 509–513 (2018). https://doi.org/10.1007/s10396-017-0852-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10396-017-0852-z