Abstract
Hepatic inflammatory pseudotumor (IPT) is a rare lesion that is frequently confused with malignant tumors. According to the latest guidelines on contrast-enhanced ultrasound, hypoenhancement of solid lesions in the portal and late phases corresponds to the wash-out phenomenon that characterizes malignancies. IPT may show rapid arterial enhancement and portal or late phase hypoenhancement, falsely suggesting malignancy. We report a case of a diagnostic error in which a multifocal IPT was misdiagnosed as hepatic metastases. The IPT developed after an endoscopic retrograde cholangiography was investigated by close follow-up with CEUS and contrast-enhanced CT.
Similar content being viewed by others
References
Koide H, Sato K, Fukusato T, et al. Spontaneous regression of hepatic inflammatory pseudotumor with primary biliary cirrhosis. World J Gastroenterol. 2006;14:1645–8.
Kafeel G, Telesinghe PU. Inflammatory pseudotumor of the liver. J Clin Pathol. 1997;50:352–3.
Isin S, Baykara M, Coskun A. Inflammatory pseudotumor of the liver with target-like appearance. Tani Girisim Radyol. 2003;9:75–7.
Kim Y, Lee J, Kim K, et al. Inflammatory pseudotumor of the liver treated by hepatic resection: a case report. Yonsei Med J. 2006;47:14–30.
Claudon M, Dietrich CF, Choi BL, et al. Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS) in the liver—update 2012: a WFUMB-EFSUMB initiative in cooperation with representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS. Ultraschall Med. 2013;34:11–29. doi:10.1055/s-0032-1325499 Epub 2012 Nov 5.
Zhang Y-L, Yin XY, Xie XY, et al. Value of contrast-enhanced ultrasonography in assessing the vascularity of liver metastases: comparison with contrast-enhanced computed tomography. J Ultrasound Med. 2010;29:1403–10.
Bhayana D, Kim TK, Jang HJ, et al. Hypervascular liver masses on contrast-enhanced ultrasound: the importance of wash out. AJR. 2010;194:977–83.
Ignee A, Piscaglia F, Ott M, et al. A benign tumor of the liver mimicking malignant liver disease—cholangiocellular adenoma. Scand J Gastroenterol. 2009;44:633–6.
Kong WT, Wang WP, Cai H, et al. The analysis of enhancement pattern of hepatic inflammatory pseudotumor on contrast-enhanced ultrasound. Abdom Imaging. 2014;39:168–74.
Conflict of interest
Antonio Corvino, Benedetta Guarino, Orlando Catalano, Fabio Corvino, Alfonso Amore, and Antonella Petrillo declare that they have no conflict of interest.
Human rights statements and informed consent
All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008.
Informed consent was obtained from the patient for being included in the study.
Written informed consent was obtained from the patient according to the Ethical Committee of our Institution.
Author information
Authors and Affiliations
Corresponding author
About this article
Cite this article
Guarino, B., Catalano, O., Corvino, A. et al. Hepatic inflammatory pseudotumor: educational value of an incorrect diagnosis at contrast-enhanced ultrasound. J Med Ultrasonics 42, 547–552 (2015). https://doi.org/10.1007/s10396-015-0624-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10396-015-0624-6