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The impact of clinical pharmacy services in Nepal in the context of current health policy: a systematic review

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A Correction to this article was published on 22 May 2019

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Abstract

Aim

The necessity of clinical pharmacy services is increasing globally, and their provision is the upcoming direction of hospital pharmacists. The aim of this review was focused on the impact of clinical pharmacy services in the Nepalese healthcare setup.

Subjects and methods

The English-language databases of Web of Science, PubMed, ScienceDirect, and Cochrane Library were searched using the following keywords: ‘pharmacy’, ‘clinical pharmacy’, pharmaceutical services’, ‘pharmacists’, pharmaceutical care’, ‘pharmacy practice’, ‘hospital pharmacy’, ‘pharmaceutical interventions’, and ‘Nepal’. Eligibility for inclusion, risk of bias assessment, and data extraction from the included studies were determined by two authors, and a narrative synthesis was conducted.

Results

This review contained a total of 14 published articles. The included studies involved the counseling and educating of patients, working as a member of the healthcare team, detecting prescribing errors, suggesting clinicians or nurses, reviewing prescriptions on the ward, giving training and monitoring of the implementation of policies, etc. The outcome of these interventions showed a reduction in the direct healthcare cost, excessive use of medicines, and prescription errors, as well as improvement in the drug utilization pattern, knowledge, as well as satisfaction of patients.

Conclusion

In order to implement and enhance clinical pharmacy services, governmental, educational, and administrative support may be needed.

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Change history

  • 22 May 2019

    The Fig. 1 was incompletely filled. The correction and corresponding data are shown below. Addition to Fig. 1 “Records identified through database searching”: <Emphasis Type="Bold">Cochrane library (</Emphasis><Emphasis Type="BoldItalic">n</Emphasis> <Emphasis Type="Bold">= 6)</Emphasis>. The original article has been corrected.

References

  • Ansari M, Rao BS, Koju R, Shakya R (2005) Impact of pharmaceutical intervention on inhalation technique. Kathmandu Univ J Sci Eng Technol 1:1–8

    Google Scholar 

  • Bista D, Saha A, Mishra P, Palaian S, Shankar PR (2009) Impact of educational intervention on the pattern and incidence of potential drug–drug interactions in Nepal. Pharm Pract (Granada) 7:242–247

    Article  Google Scholar 

  • De Rijdt T, Willems L, Simoens S (2008) Economic effects of clinical pharmacy interventions: a literature review. Am J Health Syst Pharm 65:1161–1172. https://doi.org/10.2146/ajhp070506

    Article  PubMed  Google Scholar 

  • Dingding C, Abbas M (2017) A critical review; the quest of clinical pharmacist in Pakistan government hospital, references USA and China hospital setting, to salvage the public health problems like diabetes. J Basic Clin Pharm 8:1–6

    Article  Google Scholar 

  • Ghimirey A, Sapkota B, Shrestha S, Basnet N, Shankar PR, Sapkota S (2013) Evaluation of pharmacist counseling in improving knowledge, attitude, and practice in chronic kidney disease patients. SAGE Open Med 1:2050312113516111. https://doi.org/10.1177/2050312113516111

    Article  PubMed  PubMed Central  Google Scholar 

  • Hepler CD, Strand LM (1990) Opportunities and responsibilities in pharmaceutical care. Am J Health Syst Pharm 47:533–543

    Article  CAS  Google Scholar 

  • Higgins JPT, Green S (eds) (2011) Cochrane handbook for systematic reviews of interventions. The Cochrane Collaboration

  • Holloway KA, Gautam BR, Reeves BC (2001) The effects of different kinds of user fee on prescribing costs in rural Nepal. Health Policy Plan 16:421–427

    Article  CAS  Google Scholar 

  • Holloway KA, Karkee S, Tamang A, Gurung YB, Pradhan R, Reeves BC (2008) The effect of user fees on prescribing quality in rural Nepal: two controlled pre-post studies to compare a fee per drug unit vs. a fee per drug item. Trop Med Int Health 13:541–547. https://doi.org/10.1111/j.1365-3156.2008.02032.x

    Article  PubMed  Google Scholar 

  • Isetts BJ, Schondelmeyer SW, Heaton AH, Wadd WB, Hardie NA, Artz MB (2006) Effects of collaborative drug therapy management on patients’ perceptions of care and health-related quality of life. Res Social Adm Pharm 2:129–142

    Article  Google Scholar 

  • Kaboli PJ, Hoth AB, McClimon BJ, Schnipper JL (2006) Clinical pharmacists and inpatient medical care: a systematic review. Arch Intern Med 166:955–964

    Article  Google Scholar 

  • Kafle KK, Shrestha N, Karkee SB, Prasad RR, Bhuju GB, Das PL (2005) Intervention studies on rational use of drugs in public and private sector in Nepal. Nepal Med Coll J 7:47–50

    PubMed  Google Scholar 

  • Kafle KK, Bhuju GB, Karkee SB, Prasad RR, Shrestha N, Shrestha AD, Das PL, Chataut BD, Daud M (2009) An intervention improving prescribing practices and monitoring drugs availability in a district. Nepal Med Coll J 11:217–221

    CAS  PubMed  Google Scholar 

  • Khan GM, Badri P, Parbati T, Anita D, Atul A, Deepak P, Dipendra R, Himal B, Kabita G, Nirmala K (2016) Intervention on inhalation technique of rotahaler in patients with chronic obstructive pulmonary disease and asthma. Asian J Pharm Sci 11:81–82. https://doi.org/10.1016/j.ajps.2015.11.112

    Article  Google Scholar 

  • Li J, Li Z (2018) Differences and similarities in clinical pharmacy practice in China and the United States: a narrative review. Eur J Hosp Pharm 25:2–5. https://doi.org/10.1136/ejhpharm-2016-001195

    Article  PubMed  Google Scholar 

  • Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339:b2700. https://doi.org/10.1136/bmj.b2700

    Article  PubMed  PubMed Central  Google Scholar 

  • Penm J, Li Y, Zhai S, Hu Y, Chaar B, Moles R (2014) The impact of clinical pharmacy services in China on the quality use of medicines: a systematic review in context of China’s current healthcare reform. Health Policy Plan 29:849–872. https://doi.org/10.1093/heapol/czt067

    Article  PubMed  Google Scholar 

  • Perez A, Doloresco F, Hoffman JM, Meek PD, Touchette DR, Vermeulen LC, Schumock GT (2009) Economic evaluations of clinical pharmacy services: 2001–2005. Pharmacotherapy 29:128

    Article  Google Scholar 

  • Pickard AS, Hung S-Y (2006) An update on evidence of clinical pharmacy services’ impact on health-related quality of life. Ann Pharmacother 40:1623–1634. https://doi.org/10.1345/aph.1G653

    Article  PubMed  Google Scholar 

  • Poudel RS, Shrestha S, Khatiwada D, Thapa S, Prajapati A, Thapa L, Baral R (2015) Prescription errors and pharmacist’s intervention at outpatient pharmacies of two teaching hospitals of central Nepal. World J Pharm Sci 3:448–452

    Google Scholar 

  • Poudel RS, Piryani RM, Shrestha S, Prajapati A (2016) Benefit of hospital pharmacy intervention on the current status of dry powder inhaler technique in patients with asthma and COPD: a study from the Central Development Region, Nepal. Integr Pharm Res Pract 6:7–13. https://doi.org/10.2147/IPRP.S119202

    Article  PubMed  PubMed Central  Google Scholar 

  • Ranjit E (2016) Pharmacy practice in Nepal. Can J Hosp Pharm 69:493–500

    PubMed  PubMed Central  Google Scholar 

  • Rauniar GP, Das BP, Manandhar TR, Bhattacharya SK (2014) Effectiveness of an educational feedback intervention on drug prescribing in dental practice. Kathmandu Univ Med J 10:30–35. https://doi.org/10.3126/kumj.v10i4.10991

    Article  Google Scholar 

  • Schumock GT, Butler MG, Meek PD, Vermeulen LC, Arondekar BV, Bauman JL (2003) Evidence of the economic benefit of clinical pharmacy services: 1996–2000. Pharmacotherapy 23:113–132

    Article  Google Scholar 

  • Sharma S, Bhuvan KC, Alrasheedy AA, Kaundinnyayana A, Khanal A (2014) Impact of community pharmacy-based educational intervention on patients with hypertension in Western Nepal. Australas Med J 7:304–313. https://doi.org/10.4066/AMJ.2014.2133

    Article  PubMed  PubMed Central  Google Scholar 

  • Shrestha N, Samir KC, Baltussen R, Kafle KK, Bishai D, Niessen L (2006) Practical approach to lung health in Nepal: better prescribing and reduction of cost. Trop Med Int Health 11:765–772. https://doi.org/10.1111/j.1365-3156.2006.01599.x

    Article  PubMed  Google Scholar 

  • Strand LM, Cipolle RJ, Morley PC, Frakes MJ (2004) The impact of pharmaceutical care practice on the practitioner and the patient in the ambulatory practice setting: twenty-five years of experience. Curr Pharm Des 10:3987–4001

    Article  CAS  Google Scholar 

  • Upadhyay DK, Ibrahim MIM, Mishra P, Alurkar VM (2015) A non-clinical randomised controlled trial to assess the impact of pharmaceutical care intervention on satisfaction level of newly diagnosed diabetes mellitus patients in a tertiary care teaching hospital in Nepal. BMC Health Serv Res 15:57. https://doi.org/10.1186/s12913-015-0715-5

    Article  PubMed  PubMed Central  Google Scholar 

  • Upadhyay DK, Ibrahim MIM, Mishra P, Alurkar VM, Ansari M (2016) Does pharmacist-supervised intervention through pharmaceutical care program influence direct healthcare cost burden of newly diagnosed diabetics in a tertiary care teaching hospital in Nepal: a non-clinical randomised controlled trial approach. Daru 24:6. https://doi.org/10.1186/s40199-016-0145-x

    Article  PubMed  PubMed Central  Google Scholar 

  • Viktil KK, Blix HS (2008) The impact of clinical pharmacists on drug-related problems and clinical outcomes. Basic Clin Pharmacol Toxicol 102:275–280. https://doi.org/10.1111/j.1742-7843.2007.00206.x

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

The authors greatly acknowledge Dr. Muhammad Abbas (School of Life Sciences, Nanjing University, People’s Republic of China) for his guidance and insightful comments on this manuscript. The lead author (Reyaj Mikrani) is thankful to the China Scholarship Council (CSC) for its generous financial support for him to study in China.

Funding

This work was supported by the National Natural Science Foundation of China (grant numbers 30973003 and 30901993) and the Administration of Traditional Chinese Medicine of Jiangsu Province (grant number LZ11093).

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Correspondence to Zhou Xiaohui.

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Mikrani, R., Naveed, M., Mikrani, A. et al. The impact of clinical pharmacy services in Nepal in the context of current health policy: a systematic review. J Public Health (Berl.) 28, 245–255 (2020). https://doi.org/10.1007/s10389-019-01042-y

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