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Advanced-stage tongue and mouth floor cancer is related to tobacco and alcohol abuse

  • Original Article
  • Published:
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A Publisher Correction to this article was published on 30 January 2018

This article has been updated

Abstract

Introduction

Smoking and alcoholism are recognized factors associated with the prevalence of oral cancer. However, the role of these habits on the severity of lesions still needs to be elucidated.

Objective

To evaluate the prevalence of tongue and mouth floor cancer according to the clinical stage and how it correlates with alcoholism and smoking habits in Brazil from 2000 to 2010.

Methods

Data referring to 11,873 cases of tongue and mouth floor cancer were obtained from the Integrator Module of the Hospital Registry of Cancer. Internal inconsistencies (non-classified cases) and data with no relevant information were eliminated. The final sample value considered for statistical analysis was equal to 8417 cases. An analysis of frequency distribution and binary logistic regression modeling was performed, using a significance level of 5%.

Results

The concomitant use of alcohol and tobacco (69%, n = 5808) and clinical stage grade IV (55.9%, n = 4703) were the most frequent findings. A higher prevalence of advanced lesions was observed in 2008 (PR = 1.715, 95% CI = 1.254–2.347, p < 0.01). The prevalence ratio of advanced tongue and mouth floor cancer (clinical stages III and IV) was observed to be significant for both smokers only (p < 0.01; PR = 1.460; 95% CI = 1.222–1.745) and for individuals who were both smokers and alcoholics (p < 0.05; RP = 2.279; 95% CI = 1.980–2.622).

Conclusion

Data from the 11-year registry suggest that smoking contributes significantly to the prevalence of advanced cases of tongue and mouth floor cancer. It is also implied that concomitant use of alcohol and tobacco increases the prevalence of advanced-stage oral cancer. Prospective cohort studies are still necessary to prove such relationships.

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Change history

  • 30 January 2018

    The journal had been advised to revise the title so that Clarivate Analytics can try to count the citations more accurately. There’s been confusion due to the existence of another journal with the same name.

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Authors and Affiliations

  1. UFPB Federal University of Paraiba, João Pessoa, PB, Brazil

    Natanael Victor Furtunato Bezerra, Karla Lorene de França Leite, Mariana Marinho Davino de Medeiros & Mariana Leonel Martins

  2. UEPB State University of Paraiba, Campina Grande, PB, Brazil

    Andreia Medeiros Rodrigues Cardoso

  3. Department of Dentistry, UEPB State University of Paraiba, Campina Grande, PB, Brazil

    Cassiano Francisco Weege Nonaka

  4. Clinical and Social Dentistry Department, UFPB Federal University of Paraiba, Campus I, Cidade Universitária, João Pessoa, PB, CEP 58051-900, Brazil

    Wilton Wilney Nascimento Padilha & Yuri Wanderley Cavalcanti

Authors
  1. Natanael Victor Furtunato Bezerra
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  2. Karla Lorene de França Leite
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  3. Mariana Marinho Davino de Medeiros
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  4. Mariana Leonel Martins
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  5. Andreia Medeiros Rodrigues Cardoso
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  6. Cassiano Francisco Weege Nonaka
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  7. Wilton Wilney Nascimento Padilha
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  8. Yuri Wanderley Cavalcanti
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Contributions

The authors declare the following contributions:

NVF Bezerra, AMR Cardoso, WWN Padilha and YW Cavalcanti conceptualized the study.

NVF Bezerra, KLF Leite, MMD Medeiros and ML Martins collected data.

AMR Cardoso, WWN Padilha, CFW Nonaka and YW Cavalcanti performed statistical analysis and interpreted data.

All authors contributed significantly to the writing of the manuscript and revised it critically for important the intellectual content.

All authors approved the final version of the manuscript.

Corresponding author

Correspondence to Yuri Wanderley Cavalcanti.

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Conflict of interest

The authors declare that they have no conflict of interest. No funding was received.

Ethical approval

This article does not contain any studies with human participants performed by any of the authors.

Additional information

The original version of this article was revised: Due to the existence of another journal with the same name, the Publisher has added a subtitle, “From Theory to Practice.” Effective as of January 2018, the new title of this Journal is Journal of Public Health: From Theory to Practice.

A correction to this article is available online at https://doi.org/10.1007/s10389-017-0893-1.

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Bezerra, N.V.F., de França Leite, K.L., de Medeiros, M.M.D. et al. Advanced-stage tongue and mouth floor cancer is related to tobacco and alcohol abuse. J Public Health 26, 151–156 (2018). https://doi.org/10.1007/s10389-017-0859-3

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  • DOI: https://doi.org/10.1007/s10389-017-0859-3

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