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Intraocular pressure at different gaze positions in patients with highly myopic strabismus

  • Clinical Investigation
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To evaluate intraocular pressure (IOP) at different gaze positions in patients with highly myopic strabismus (HMS).

Study design

Nonrandomized, prospective, observational study.

Methods

This study included 18 eyes of 14 patients with HMS and 51 eyes of 51 age-matched controls without strabismus; these were further divided into two groups based on refractive errors: > -6.00 diopter (D) (n = 22 eyes) and ≤ -6.00 D (n = 29 eyes). IOP was measured in primary and side gazes and compared within and among groups. The relationships between IOPs and axial length, angle of globe dislocation measured on magnetic resonance imaging, strabismus angle, and degree of abduction deficit were studied.

Results

The HMS group showed higher IOP in abduction (19.3 ± 4.9 mmHg) than in the primary (12.5 ± 4.3 mmHg) and adducting positions (13.0 ± 3.3 mmHg), (p < 0.001). The IOP in the adducting position in the HMS group (13.0 ± 3.3 mmHg) was lower than in the control groups both with (17.6 ± 3.5 mmHg) and without (16.9 ± 4.1 mmHg) high myopia, ; (p < 0.001 and = 0.003). The difference in IOP between abduction and adduction was significantly larger in the HMS group (6.4 ± 4.6 mmHg) compared to others (p < 0.001) and positively correlated with the strabismus angle and the angle of globe dislocation and negatively with abduction deficit.

Conclusion

The IOP of patients with HMS changes dramatically on side gazes, therefore, care should be taken while measuring IOP.

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Data availability

The data that support the findings of this study are available on request from the corresponding author, [M.S.].

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Acknowledgements

We thank Editage for English language editing.

Funding

JSPS KAKENHI Grant Number, 16K11264.

Author information

Authors and Affiliations

  1. Department of Ophthalmology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, 431-3125, Hamamatsu City, Shizuoka, Japan

    Shinji Arai, Hiroko Suzuki, Risako Inagaki, Takashi Haseoka, Akiko Hikoya, Miwa Komori, Tamami Shimizu, Nazmul Haque Muhammad, Yoshihiro Hotta & Miho Sato

  2. Department of Ophthalmology, Yamagata University Faculty of Medicine, 2-2-2 Iidanishi, 990-9585, Yamagata City, Yamagata, Japan

    Shion Hayashi

  3. Laboratory for Visual Science, Department of Ophthalmology, National Center for Child Health and Development, 2-10-1 Okura Setagaya-ku, Tokyo, Japan

    Shion Hayashi

Authors
  1. Shinji Arai
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  2. Hiroko Suzuki
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  3. Shion Hayashi
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  4. Risako Inagaki
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  5. Takashi Haseoka
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  6. Akiko Hikoya
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  7. Miwa Komori
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  8. Tamami Shimizu
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  9. Nazmul Haque Muhammad
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  10. Yoshihiro Hotta
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  11. Miho Sato
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Corresponding author

Correspondence to Miho Sato.

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Conflict of interest

S. Arai, None; H. Suzuki, None; S. Hayashi, None; R. Inagaki, None; T. Haseoka, None; A. Hikoya, None; M. Komori, None; T. Shimizu, None; N. H. Muhammad, None; Y. Hotta, None; M. Sato, None.

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Corresponding Author: Miho Sato

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Arai, S., Suzuki, H., Hayashi, S. et al. Intraocular pressure at different gaze positions in patients with highly myopic strabismus. Jpn J Ophthalmol 66, 572–578 (2022). https://doi.org/10.1007/s10384-022-00939-8

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  • DOI: https://doi.org/10.1007/s10384-022-00939-8

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