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Long-term outcomes of Descemet stripping automated endothelial keratoplasty for bullous keratopathy after argon laser iridotomy

  • Clinical Investigation
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To report the long-term outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) for bullous keratopathy secondary to argon laser iridotomy (BK-ALI).

Study design

Retrospective chart review.

Methods

Forty-five eyes from 41 consecutive patients with BK-ALI who underwent DSAEK from July 2007 to December 2013 were retrospectively analyzed. Best spectacle-corrected visual acuity (BCVA), endothelial cell density (ECD), and any complications were investigated over a 10-year postoperative period.

Results

The mean BCVA improved from 0.80 logMAR before DSAEK to 0.28 logMAR at 6 months after DSAEK; the mean values showed an additional slight improvement between 6 months and 10 years after the surgery (P < .01). The mean ECD decreased from 2864 cells/mm2 at baseline to 2269 cells/mm2 (20.8% loss) at 6 months post-DSAEK, and this decreasing trend continued throughout the 10 years after DSAEK (P < .01). The mean ECD was 1148 cells/mm2 (59.9% loss) after 5 years, and 568 cells/mm2 (80.2% loss) after 10 years. No graft deaths were observed throughout the 10-year period (5-year follow-up rate 60.0%, 10-year follow-up rate 20.0%).

Conclusions

The 10-year outcomes of DSAEK for BK-ALI were excellent with a high graft survival rate.

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Acknowledgements

This study supported by Grant-in-Aid for Scientific Research (C) Kakenhi, Japan (19K09947).

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Authors and Affiliations

  1. Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Takara-machi 13-1, Kanazawa, Ishikawa-ken, 920-8641, Japan

    Yunyan Ye, Natsuko Mori, Akira Kobayashi, Hideaki Yokogawa & Kazuhisa Sugiyama

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  1. Yunyan Ye
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  2. Natsuko Mori
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  3. Akira Kobayashi
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  4. Hideaki Yokogawa
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  5. Kazuhisa Sugiyama
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Corresponding author

Correspondence to Hideaki Yokogawa.

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Conflicts of interest

Y. Ye, None; N. Mori, None; A. Kobayashi, None; H. Yokogawa, None; K. Sugiyama, None.

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Corresponding Author: Hideaki Yokogawa

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Ye, Y., Mori, N., Kobayashi, A. et al. Long-term outcomes of Descemet stripping automated endothelial keratoplasty for bullous keratopathy after argon laser iridotomy. Jpn J Ophthalmol 65, 454–459 (2021). https://doi.org/10.1007/s10384-021-00832-w

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  • DOI: https://doi.org/10.1007/s10384-021-00832-w

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