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Eyelid cleansing with ointment for obstructive meibomian gland dysfunction

  • Clinical Investigation
  • Published:
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Abstract

Purpose

To investigate the efficacy of eyelid margin cleansing with ofloxacin ophthalmic ointment in obstructive meibomian gland dysfunction (MGD) patients.

Methods

Thirty-one eyes of 31 patients diagnosed with obstructive MGD were enrolled. All subjects were instructed to rub the eyelid edge with ofloxacin eye ointment once daily prior to bathing. Lid margin abnormalities, meibum properties, and tear stability were observed before and 3 months after ointment treatment. A questionnaire relating to the severity of MGD symptoms was administered after the treatment.

Results

Vascular engorgement, meibum, dandruff-like debris, and fluorescein staining scores significantly decreased after the treatment, whereas tear break-up time significantly increased (p < 0.05). Symptoms related to MGD improved after the treatment in 86.2 % of cases.

Conclusions

Cleansing treatment ofloxacin ophthalmic ointment at the eyelid margin may be effective for patients with obstructive MGD.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan

    Minako Kaido, Osama M. A. Ibrahim, Motoko Kawashima, Reiko Ishida, Enrique A. Sato & Kazuo Tsubota

  2. Wada Eye Clinic, Chiba, Japan

    Minako Kaido

  3. Ishida Eye Clinic, Shizuoka, Japan

    Reiko Ishida

Authors
  1. Minako Kaido
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  2. Osama M. A. Ibrahim
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  3. Motoko Kawashima
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  4. Reiko Ishida
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  5. Enrique A. Sato
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  6. Kazuo Tsubota
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Corresponding author

Correspondence to Minako Kaido.

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Conflicts of interest

M. Kaido, None; O. M. A. Ibrahim, None; M. Kawashima, None; R. Ishida, None; E. A. Sato, None; K. Tsubota, Consultant fees (Santen).

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Cite this article

Kaido, M., Ibrahim, O.M.A., Kawashima, M. et al. Eyelid cleansing with ointment for obstructive meibomian gland dysfunction. Jpn J Ophthalmol 61, 124–130 (2017). https://doi.org/10.1007/s10384-016-0477-6

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  • DOI: https://doi.org/10.1007/s10384-016-0477-6

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