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Bilateral papillomacular retinoschisis and macular detachment accompanied by focal lamina cribrosa defect in glaucomatous eyes

  • Clinical Investigation
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

We report here a patient with bilateral papillomacular retinoschisis with an enlarged glaucomatous optic nerve head cup and a focal lamina cribrosa defect, the findings of our clinical investigations of this case, and the chosen treatment and outcome.

Design

This is an observational case report.

Methods

Clinical examinations were performed using simultaneous confocal scanning laser ophthalmoscopy and optical coherence tomography (OCT). The patient was treated by pars plana vitrectomy (PPV).

Results

The left eye had a macular detachment with a presumed acquired pit of the optic nerve, while the right eye did not have an obvious optic nerve pit. Enhanced depth imaging OCT showed focal lamina cribrosa defects in both eyes. PPV was performed on the left eye, which resulted in a re-attachment of the macula and improvement of the visual acuity.

Conclusions

Our findings suggest that the pathological changes were most likely due to focal lamina cribrosa defects in both glaucomatous eyes. This type of maculopathy can be successfully treated with PPV.

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References

  1. Kranenburg EW. Crater-like holes in the optic disc and central serous retinopathy. Arch Ophthalmol. 1960;64:912–24.

    Article  PubMed  CAS  Google Scholar 

  2. Ferry AP. Macular detachment associated with congenital pit of the optic nerve head: pathologic findings in two cases simulating malignant melanoma of the choroid. Arch Ophthalmol. 1963;70:346–57.

    Article  PubMed  CAS  Google Scholar 

  3. Gass JD. Serous detachment of the macula. Secondary to congenital pit of the optic nerve head. Am J Ophthalmol. 1969;67:821–41.

    PubMed  CAS  Google Scholar 

  4. Brockhurst RJ. Optic pits and posterior retinal detachment. Trans Am Ophthalmol Soc. 1975;73:264–91.

    PubMed  CAS  PubMed Central  Google Scholar 

  5. Brown GC, Shields JA, Goldberg RE. Congenital pits of the optic nerve head. II. Clinical studies in humans. Ophthalmology. 1980;87:51–65.

    Article  PubMed  CAS  Google Scholar 

  6. Lincoff H, Lopez R, Kreissig I, Yannuzzi L, Cox M, Burton T. Retinoschisis associated with optic nerve pits. Arch Ophthalmol. 1988;106:61–7.

    Article  PubMed  CAS  Google Scholar 

  7. Apple DJ, Rabb MF, Walsh PM. Congenital anomalies of the optic disc. Surv Ophthalmol. 1982;27:3–41.

    Article  PubMed  CAS  Google Scholar 

  8. Georgalas I, Ladas I, Georgopoulos G, Petrou P. Optic disc pit: a review. Graefes Arch Clin Exp Ophthalmol. 2011;249:1113–22.

    Article  PubMed  Google Scholar 

  9. Sobol WM, Blodi CF, Folk JC, Weingeist TA. Long-term visual outcome in patients with optic nerve pit and serous retinal detachment of the macula. Ophthalmology. 1990;97:1539–42.

    Article  PubMed  CAS  Google Scholar 

  10. Hirakata A, Okada AA, Hida T. Long-term results of vitrectomy without laser treatment for macular detachment associated with an optic disc pit. Ophthalmology. 2005;112:1430–5.

    Article  PubMed  Google Scholar 

  11. Hirakata A, Inoue M, Hiraoka T, McCuen BW II. Vitrectomy without laser treatment or gas tamponade for macular detachment associated with an optic disc pit. Ophthalmology. 2012;119:810–8.

    Article  PubMed  Google Scholar 

  12. Hamada S, Yoshida K, Chihara E. Pseudo-disc-pits.macular syndrome. Nihon Ganka Gakkai Zasshi. 2001;105:338–42 (in Japanese).

    PubMed  CAS  Google Scholar 

  13. Spaide RF, Costa DL, Huang SJ. Macular schisis in a patient without an optic disk pit optical coherence tomographic findings. Retina. 2003;23:238–40.

    Article  PubMed  Google Scholar 

  14. Hotta K. Unsuccessful vitrectomy without gas tamponade for macular retinal detachment and retinoschisis without optic disc pit. Ophthalmic Surg Lasers Imaging. 2004;35:328–31.

    PubMed  Google Scholar 

  15. Hollander DA, Barricks ME, Duncan JL, Irvine AR. Macular schisis detachment associated with angle-closure glaucoma. Arch Ophthalmol. 2005;123:270–2.

    Article  PubMed  Google Scholar 

  16. Perkins SL, Han DP, Gonder JR, Beaumont PE, Colev G. Dynamic atypical optic nerve coloboma associated with transient macular detachment. Arch Ophthalmol. 2005;123:1750–4.

    Article  PubMed  Google Scholar 

  17. Zumbro DS, Jampol LM, Folk JC, Olivier MM, Anderson-Nelson S. Macular schisis and detachment associated with presumed acquired enlarged optic nerve head cups. Am J Ophthalmol. 2007;144:70–4.

    Article  PubMed  Google Scholar 

  18. Farjad H, Besada E, Frauens BJ. Peripapillary schisis with serous detachment in advanced glaucoma. Optom Vis Sci. 2010;87:E205–17.

    Article  PubMed  Google Scholar 

  19. Pokroy R, Desai UR. Bilateral optic pit-like maculopathy with normal optic nerve heads. Can J Ophthalmol. 2010;45:415–6.

    Article  PubMed  Google Scholar 

  20. Zhao M, Li X. Macular retinoschisis associated with normal tension glaucoma. Graefes Arch Clin Exp Ophthalmol. 2011;249:1255–8.

    Article  PubMed  Google Scholar 

  21. Moreno-Lopez M, Gonzalez-Lopez JJ, Jarrin E, Bertrand J. Retinoschisis and macular detachment associated with acquired enlarged optic disc cup. Clin Ophthalmol. 2012;6:433–6.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Hedels C, Krohn J. Enhanced depth imaging optical coherence tomography of optic disc maculopathy without a visible optic pit. Clin Experiment Ophthalmol. 2013;41:894–6.

    Article  PubMed  Google Scholar 

  23. Radius RL, Maumenee AE, Green WR. Pit-like changes of the optic nerve head in open-angle glaucoma. Br J Ophthalmol. 1978;62:389–93.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  24. Rath EZ, Rumelt S. Acute visual loss due to serous retinal detachment from acquired optic pit may be a rare presentation of primary open-angle glaucoma. Can J Ophthalmol. 2007;42:339–40.

    Article  PubMed  Google Scholar 

  25. Song IS, Shin JW, Shin YW, Uhm KB. Optic disc pit with peripapillary retinoschisis presenting as a localized retinal nerve fiber layer defect. Korean J Ophthalmol. 2011;25:455–8.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain optical coherence tomography. Am J Ophthalmol. 2008;146:496–500.

    Article  PubMed  Google Scholar 

  27. Kiumehr S, Park SC, Syril D, Teng CC, Tello C, Liebmann J, et al. In vivo evaluation of focal lamina cribrosa defects in glaucoma. Arch Ophthalmol. 2012;130:552–9.

    Article  PubMed  Google Scholar 

  28. Park SC, De Moraes CG, Teng CC, Tello C, Liebmann JM, Ritch R. Enhanced depth imaging optical coherence tomography of deep optic nerve complex structures in glaucoma. Ophthalmology. 2012;119:3–9.

    Article  PubMed  Google Scholar 

  29. You JY, Park SC, Su D, Teng CC, Liebmann JM, Ritch R. Focal lamina cribrosa defects associated with glaucomatous rim thinning and acquired pits. JAMA Ophthalmol. 2013;131:314–20.

    Article  PubMed  Google Scholar 

  30. Javitt JC, Spaeth GL, Katz LJ, Poryzees E, Addiego R. Acquired pits of the optic nerve. Increased prevalence in patients with low-tension glaucoma. Ophthalmology. 1990;97:1038–43.

    Article  PubMed  CAS  Google Scholar 

  31. Nduaguba C, Ugurlu S, Caprioli J. Acquired pits of the optic nerve in glaucoma: prevalence and associated visual field loss. Acta Ophthalmol Scand. 1998;76:273–7.

    Article  PubMed  CAS  Google Scholar 

  32. Ugurlu S, Weitzman M, Nduaguba C, Caprioli J. Acquired pit of the optic nerve: a risk factor for progression of glaucoma. Am J Ophthalmol. 1998;125:457–64.

    Article  PubMed  CAS  Google Scholar 

  33. Healey PR, Mitchell P. The prevalence of optic disc pits and their relationship to glaucoma. J Glaucoma. 2008;17:11–4.

    Article  PubMed  Google Scholar 

  34. Hirakata A, Hida T, Ogasawara A, Iizuka N. Multilayered retinoschisis associated with optic disc pit. Jpn J Ophthalmol. 2005;49:414–6.

    Article  PubMed  Google Scholar 

  35. Roy R, Waanbah AD, Mathur G, Raman R, Sharma T. Optical coherence tomography characteristics in eyes with optic pit maculopathy. Retina. 2013;33:771–5.

    Article  PubMed  Google Scholar 

  36. Hirakata A, Hida T, Wakabayashi T, Fukuda M. Unusual posterior hyaloid strand in a young child with optic disc pit maculopathy: intraoperative and histopathological findings. Jpn J Ophthalmol. 2005;49:264–6.

    Article  PubMed  Google Scholar 

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Acknowledgments

The authors thank Dr. Masanori Hangai for his support in the data interpretation.

Conflicts of interest

T. Yoshitake, None; H. Nakanishi, None; Y. Setoguchi, None; K. Kuroda, None; K. Amemiya, None; M. Taniguchi, None; A. Otani, None.

Author information

Authors and Affiliations

  1. Department of Ophthalmology, Japanese Red Cross Society Wakayama Medical Center, 4-20 Komatsubaradouri, Wakayama City, Wakayama, 640-8558, Japan

    Tatsuya Yoshitake, Hideo Nakanishi, Yoshinao Setoguchi, Kenichi Kuroda, Kaori Amemiya, Misa Taniguchi & Atsushi Otani

  2. Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Hideo Nakanishi

Authors
  1. Tatsuya Yoshitake
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  2. Hideo Nakanishi
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  3. Yoshinao Setoguchi
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  4. Kenichi Kuroda
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  5. Kaori Amemiya
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  6. Misa Taniguchi
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  7. Atsushi Otani
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Correspondence to Hideo Nakanishi.

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Yoshitake, T., Nakanishi, H., Setoguchi, Y. et al. Bilateral papillomacular retinoschisis and macular detachment accompanied by focal lamina cribrosa defect in glaucomatous eyes. Jpn J Ophthalmol 58, 435–442 (2014). https://doi.org/10.1007/s10384-014-0330-8

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  • DOI: https://doi.org/10.1007/s10384-014-0330-8

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