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System Design and Emerging Hardware Technology for Ion Chromatography

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Abstract

This review provides an overview of advances in system design for ion chromatography (IC), focusing on the suppressed conductivity detection mode. In particular, advances in automated mobile-phase generation and suppressor technology based on different electrolytic concepts are addressed and novel detection approaches are discussed. Finally, advances in multi-dimensional IC and aspects of miniaturization, including capillary IC instrumentation and chip-based IC, are discussed.

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Fig. 1

Reprinted (adapted) from [30] with permission. ©2008 American Chemical Society

Fig. 2

Reprinted (adapted) from [35] with permission. © 2012 American Chemical Society

Fig. 3

Reprinted (adapted) from [51] with permission. © 2015 Elsevier

Fig. 4

Reprinted (Adapted) from [62] with permission. © 2016 Elsevier

Fig. 5

Reprinted (Adapted) from [63] with permission. © 2015 American Chemical Society

Fig. 6

Reprinted (Adapted) from [73] with permission. © 2010 American Chemical Society

Fig. 7

Reprinted (Adapted) from [83] with permission. © 2010 Elsevier

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Abbreviations

AEM:

Anion-exchange membrane

C4D:

Capacitively coupled contactless conductivity detection

CEM:

Cation-exchange membrane

EEG:

Electrolytic eluent generator

IC:

Ion chromatography

IEX:

Ion-exchange chromatography

LOD:

Limit of detection

PEEK:

Poly(ether ether ketone)

RP-LC:

Reversed-phase liquid chromatography

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Acknowledgments

Support of this work by grants of the Research Foundation Flanders (FWO) and a PhD grant of the Flemish Agency of Innovation and Entrepreneurship (VLAIO) are gratefully acknowledged.

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Authors and Affiliations

  1. Department of Chemical Engineering, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussels, Belgium

    Sam Wouters & Sebastiaan Eeltink

  2. School of Physical Sciences, University of Tasmania, Private Bag 75, Hobart, TAS, 7001, Australia

    Paul R. Haddad

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  1. Sam Wouters
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Correspondence to Sebastiaan Eeltink.

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Published in the topical collection Young Investigators in Separation Science with editors D. Mangelings, G. Massolini, G. K. E. Scriba, R. M. Smith and A. M. Striegel.

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Wouters, S., Haddad, P.R. & Eeltink, S. System Design and Emerging Hardware Technology for Ion Chromatography. Chromatographia 80, 689–704 (2017). https://doi.org/10.1007/s10337-016-3184-z

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