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Viral seroprevalence in northern pig-tailed macaques (Macaca leonina) derived from Ho Chi Minh City, Vietnam

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Abstract

Non-human primates are natural virus reservoirs, whether wild or domestic. In this study, we determined the seroprevalence of common viruses by ELISA in a northern pig-tailed macaque (Macaca leonina) colony derived from Ho Chi Minh City, Vietnam. A total of 20 types of virus which are commonly selected as target microorganisms for specific-pathogen-free colonies, or which have zoonotic potential were included in this study. The results showed only 2 in 90 northern pig-tailed macaques were seronegative for all the detected viruses, and at least 16 out of the total 20 types of virus tested were prevalent in this colony, so these macaques were commonly infected by various viruses. These macaques should be carefully assessed for viral seroprevalence in order to prevent zoonotic diseases from being transferred to human beings.

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Acknowledgments

This work was supported partly by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81273251, U1202228), the Knowledge Innovation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), and the Key Scientific and Technological Program of China (2012ZX10001-007, 2013ZX10001-002). We thank Mr. Long-Bao Lv, and all the members from Kunming Primate Research Center, Kunming Institute of Zoology, CAS who provided assistance with the sample collection. We thank Prof. Muhammad Shahzad and Dr. Xin Chen for their assistance with editing. We complied with the ethical standards in the treatment of the animals with the guidelines laid down by NIH (US).

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Authors and Affiliations

  1. Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223, Yunnan, China

    Ming-Xu Zhang, Hong-Yi Zheng, Jin Jiang, Wei Pang, Gao-Hong Zhang & Yong-Tang Zheng

  2. Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, 650204, Yunnan, China

    Ming-Xu Zhang & Jin Jiang

  3. School of Life Sciences, University of Science and Technology of China, Hefei, 230026, Anhui, China

    Hong-Yi Zheng

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  1. Ming-Xu Zhang
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  2. Hong-Yi Zheng
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  3. Jin Jiang
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  4. Wei Pang
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Correspondence to Yong-Tang Zheng.

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10329_2016_531_MOESM1_ESM.tif

Supplementary Fig. 1. OD values of different viruses in each age group. The OD values are shown as mean. The abbreviation in this figure is the same as in Table 2. 1 (TIFF 75431 kb)

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Zhang, MX., Zheng, HY., Jiang, J. et al. Viral seroprevalence in northern pig-tailed macaques (Macaca leonina) derived from Ho Chi Minh City, Vietnam. Primates 57, 413–419 (2016). https://doi.org/10.1007/s10329-016-0531-5

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  • DOI: https://doi.org/10.1007/s10329-016-0531-5

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