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The effect of diabetes on the tensile bond strength of a restorative dental composite to dentin

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Abstract

This study was performed to evaluate the effect of diabetes mellitus (DM) on the tensile bond strength (TBS) of dental composite resin bonding to enamel and dentin of extracted human teeth. Thirty caries-free human premolar teeth (10 from type 1 DM (D1), 10 from type 2 DM (D2), and 10 from non-diabetic individuals (control)) were wet ground and polished to obtain flat surfaces of dentin (n = 10). 37% phosphoric acid was used to etch dentin specimens for 15 s. After the application of the adhesive system, the composite resins were applied and cured for 20 s. Then, specimens were subjected to TBS testing by Universal Testing Machine (1 mm/min). One specimen from each group was prepared and observed under a scanning electron microscope (SEM) and a dot map was generated. Data were analyzed by ANOVA and post hoc Tukey tests (α = 0.05). The TBS values were significantly higher in the control group compared to the D1 and D2 groups (P < 0.05). Between DM groups, D2 values were significantly higher than those in the D1 group. Unlike DM groups, the zigzag fracture pattern was only noticed in the control group. DM adversely affected the TBS of dental composite resins to dentin; this negative effect is more exaggerated by type 1 DM than type 2 DM.

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References

  1. Araki E, Miyazaki J-I. Metabolic disorders in diabetes mellitus: impact of mitochondrial function and oxidative stress on diabetes and its complications. Antioxid Redox Signal. 2007;9(3):289–91.

    Article  PubMed  Google Scholar 

  2. Papapanou PN. Periodontal diseases: epidemiology. Ann Periodontol. 1996;1(1):1–36.

    Article  PubMed  Google Scholar 

  3. Fouad AF. Diabetes mellitus as a modulating factor of endodontic infections. J Dent Educ. 2003;67(4):459–67.

    Article  PubMed  Google Scholar 

  4. Mealey BL, Moritz AJ. Hormonal influences: effects of diabetes mellitus and endogenous female sex steroid hormones on the periodontium. Periodontol. 2003;32(1):59–81.

    Article  Google Scholar 

  5. De Pommereau V, et al. Periodontal status in insulin-dependent diabetic adolescents. J Clin Periodontol. 1992;19(9):628–32.

    Article  PubMed  Google Scholar 

  6. Gusberti F, et al. Puberty gingivitis in insulin-dependent diabetic children: I cross-sectional observations. J Periodontol. 1983;54(12):714–20.

    Article  PubMed  Google Scholar 

  7. Sastrowijoto S, et al. Improved metabolic control, clinical periodontal status and subgingival microbiology in insulin-dependent diabetes mellitus: a prospective study. J Clin Periodontol. 1990;17(4):233–42.

    Article  PubMed  Google Scholar 

  8. Karjalainen KM, Knuuttila ML. The onset of diabetes and poor metabolic control increases gingival bleeding in children and adolescents with insulin-dependent diabetes mellitus. J Clin Periodontol. 1996;23(12):1060–7.

    Article  PubMed  Google Scholar 

  9. Bačić M, Plančak D, Granić M. CPITN assessment of periodontal disease in diabetic patients. J Periodontol. 1988;59(12):816–22.

    Article  PubMed  Google Scholar 

  10. Emrich LJ, Shlossman M, Genco RJ. Periodontal disease in non-insulin-dependent diabetes mellitus. J Periodontol. 1991;62(2):123–31.

    Article  PubMed  Google Scholar 

  11. Shlossman M, et al. Type 2 diabetes mellitus and periodontal disease. J Am Dent Assoc. 1990;121(4):532–6.

    Article  PubMed  Google Scholar 

  12. Collin H-L, et al. Caries in patients with non-insulin-dependent diabetes mellitus. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 1998;85(6):680–5.

    Article  Google Scholar 

  13. Moore PA, et al. Type 1 diabetes mellitus and oral health: assessment of coronal and root caries. Commun Dent Oral Epidemiol. 2001;29(3):183–94.

    Article  Google Scholar 

  14. Lin B, et al. Dental caries in older adults with diabetes mellitus. Spec Care Dentist. 1999;19(1):8–14.

    Article  PubMed  Google Scholar 

  15. Twetman S, et al. Caries incidence in young type 1 diabetes mellitus patients in relation to metabolic control and caries-associated risk factors. Caries Res. 2002;36(1):31–5.

    Article  PubMed  Google Scholar 

  16. Iughetti L, et al. Oral health in children and adolescents with IDDM-a review. J Pediatr Endocrinol Metab. 1999;12(5):603–10.

    Article  PubMed  Google Scholar 

  17. Miralles Jordá, L., et al., Dental caries in type 1 diabetics: influence of systemic factors of the disease upon the development of dental caries. 2006.

  18. Garber SE, et al. The effect of hyperglycemia on pulpal healing in rats. J Endod. 2009;35(1):60–2.

    Article  PubMed  Google Scholar 

  19. Bin G, et al. Altered circadian rhythm of pulp sensibility in elderly diabetic and hypertensive patients. Chin Med J. 2007;120(11):1024–6.

    Article  Google Scholar 

  20. Zhang Y-R, et al. Review of research on the mechanical properties of the human tooth. Int J Oral Sci. 2014;6(2):61–9.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Lu QL, et al. Bcl-2 expression in adult and embryonic non-haematopoietic tissues. J Pathol. 1993;169(4):431–7.

    Article  PubMed  Google Scholar 

  22. Shirzaiy M, et al. Estimation of salivary sodium, potassium, calcium, phosphorus and urea in type II diabetic patients. Diabetes Metab Syndr. 2015;9(4):332–6.

    Article  PubMed  Google Scholar 

  23. Saghiri MA, et al. Effect of diabetes on tubular density and push-out bond strength of MTA to dentin. J Endod. 2020. https://doi.org/10.1016/j.joen.2020.07.025.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Sudsangiam S, van Noort R. Do dentin bond strength tests serve a useful purpose. J Adhes Dent. 1999;1(1):57–67.

    PubMed  Google Scholar 

  25. Yamazaki PC, Bedran-Russo AK, Pereira PN. Importance of the hybrid layer on the bond strength of restorations subjected to cyclic loading. J Biomed Mater Res B Appl Biomater. 2008;84(1):291–7.

    Article  PubMed  Google Scholar 

  26. Betancourt DE, Baldion PA, Castellanos JE. Resin–dentin bonding interface: mechanisms of degradation and strategies for stabilization of the hybrid layer. Int J Biomater. 2019;2019:5268342.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Burke F, et al. Methods used in dentine bonding tests: an analysis of 102 investigations on bond strength. Eur J Prosthodont Restor Dent. 2008;16(4):158–65.

    PubMed  Google Scholar 

  28. Saghiri, et al. The effect of diabetes mellitus on the shear bond strength of composite resin to dentin and enamel. Odontology. 2021. https://doi.org/10.1007/s10266-021-00641-0.

    Article  PubMed  Google Scholar 

  29. Saghiri MA, et al. A novel polyurethane expandable root canal sealer. J Endod. 2020. https://doi.org/10.1016/j.joen.2020.12.007.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Sano H, et al. The tensile bond strength test: Its historical background and application to bond testing. Jpn Dent Sci Rev. 2020;56(1):24–31.

    Article  PubMed  Google Scholar 

  31. Frankenberger R, et al. Operator vs. material influence on clinical outcome of bonded ceramic inlays. Dent Mater. 2009;25(8):960–8.

    Article  PubMed  Google Scholar 

  32. Lohbauer U, et al. Correlation of in vitro fatigue data and in vivo clinical performance of a glassceramic material. Dent Mater. 2008;24(1):39–44.

    Article  PubMed  Google Scholar 

  33. Silva EM, et al. Influence of organic acids present in the oral biofilm on the tensile bond strength of adhesive systems to human dentin. J Biomed Mater Res B Appl Biomater. 2012;100B(3):735–41.

    Article  Google Scholar 

  34. Pribadi N, Soetojo A. Effects of different saliva pH on hybrid composite resin surface roughness. Dent J. 2011;44:63.

    Google Scholar 

  35. Abou Neel EA, et al. Demineralization-remineralization dynamics in teeth and bone. Int J Nanomed. 2016;11:4743–63.

    Article  Google Scholar 

  36. Shillitoe E, et al. The oral microflora in obesity and type-2 diabetes. J Oral Microbiol. 2012;4:19013.

    Article  Google Scholar 

  37. Yeh C-K, et al. Hyperglycemia and xerostomia are key determinants of tooth decay in type 1 diabetic mice. Lab Invest. 2012;92(6):868–82.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Arrieta-Blanco JJ, et al. Dental problems in patients with diabetes mellitus (II): gingival index and periodontal disease. Med Oral. 2003;8(4):233–47.

    PubMed  Google Scholar 

  39. Casagrande L, et al. Longevity and associated risk factors in adhesive restorations of young permanent teeth after complete and selective caries removal: a retrospective study. Clin Oral Invest. 2017;21(3):847–55.

    Article  Google Scholar 

  40. Culshaw S. Periodontal disease: its impact on restorative dentistry. Prim Dent J. 2017;6(1):25–31.

    Article  PubMed  Google Scholar 

  41. Kikushima D, et al. Micro-shear bond strength of adhesive systems to cementum. Am J Dent. 2005;18(5):364–8.

    PubMed  Google Scholar 

  42. Abbassy MA, et al. Diabetes detrimental effects on enamel and dentine formation. J Dent. 2015;43(5):589–96.

    Article  PubMed  Google Scholar 

  43. Atar M, et al. Enamel mineral concentration in diabetic rodents. Eur Arch Paediatr Dent. 2007;8(4):195–200.

    Article  PubMed  Google Scholar 

  44. Delaviz Y, Finer Y, Santerre JP. Biodegradation of resin composites and adhesives by oral bacteria and saliva: a rationale for new material designs that consider the clinical environment and treatment challenges. Dent Mater. 2014;30(1):16–32.

    Article  PubMed  Google Scholar 

  45. Sajjanhar I, Chandra A, Tikku A. Matrix metalloproteinases: its effect on dentin bonding. J Biol Nat. 2017;7:118–22.

    Google Scholar 

  46. Gupta N, et al. The influence of type 2 diabetes mellitus on salivary matrix metalloproteinase-8 levels and periodontal parameters: a study in an Indian population. Eur J Dent. 2015;9(3):319–23.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Saghiri MA, Saghiri AM. In Memoriam: Dr. Hajar Afsar Lajevardi MD, MSc, MS (1955–2015). Iran J Pediatr. 2017;27(1):1.

    Google Scholar 

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Acknowledgements

MAS is a recipient of the New Jersey Health Foundation Award. This publication is dedicated to the memory of Dr. H. Afsar Lajevardi, a legendry pediatrician (1953–2015) [47]. We will never forget Dr. H Afsar Lajevardi’s kindness and support. The views expressed in this paper are those of the authors and do not necessarily reflect the views or policies of the affiliated organizations. The authors hereby announced that they have active cooperation in this scientific study and preparation of the present manuscript. The authors confirm that they have no financial involvement with any commercial company or organization with direct financial interest regarding the materials used in this study. The authors offer special thanks to Dr. Amir Fakhrzadeh for the help in collecting the teeth for use in this current study and to Dr. Saied Amini for helping us conduct the statistical analyses.

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Authors and Affiliations

  1. Department of Restorative Dentistry, Rutgers School of Dental Medicine, MSB C639A-Rutgers Biomedical and Health Sciences, 185 South Orange Avenue, Newark, NJ, 07103, USA

    Mohammad Ali Saghiri

  2. Department of Endodontics, University of the Pacific, Arthur A. Dugoni School of Dentistry, San Francisco, CA, USA

    Mohammad Ali Saghiri

  3. Hackensack, NJ, USA

    Peter Freag

  4. Biomaterial and Prosthodontic Laboratory, Department of Restorative Dentistry, Rutgers School of Dental Medicine, Newark, NJ, USA

    Devyani Nath

  5. Department of Restorative Dentistry, Rutgers School of Dental Medicine, Newark, NJ, USA

    Steven M. Morgano

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  1. Mohammad Ali Saghiri
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  2. Peter Freag
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  3. Devyani Nath
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  4. Steven M. Morgano
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Contributions

Conceptualization and methodology: MAS, SMM; investigation: MAS, DN, PF; formal analysis: MAS, DN; writing—original draft: DN, PF; writing—review and editing: MAS, DN, PF, SMM.

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Correspondence to Mohammad Ali Saghiri.

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Saghiri, M.A., Freag, P., Nath, D. et al. The effect of diabetes on the tensile bond strength of a restorative dental composite to dentin. Odontology 110, 648–654 (2022). https://doi.org/10.1007/s10266-022-00697-6

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  • DOI: https://doi.org/10.1007/s10266-022-00697-6

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