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Provision of health care services and regional diversity in Germany: insights from a Bayesian health frontier analysis with spatial dependencies

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Abstract

The German health care system is among the most patient-oriented systems in Europe. Nevertheless, distinct utilisation patterns, access barriers due to socio-economic profiles, and potentials of misallocation of medical resources lead to disparities in the provision of health care services. We analyse how a possible over- and undersupply of services and the utilisation of and the access to the health care system relate to regional variations in the population’s well-being. For this purpose, we employ a recent Bayesian stochastic frontier approach that allows for spatial dependence structures. Our results indicate that patient migration plays an important role in contributing to regional differences in the utilisation of the medical infrastructure. As a consequence, policy should take spatial patterns of health care utilisation into account to improve the allocation of medical resources.

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Notes

  1. The software is freely available from https://www.uni-goettingen.de/en/550513.html.

  2. For a detailed description of the variables, see Herwartz and Schley [34].

  3. As mortality can be seen as an undesirable output in a health production context, we invert the SMR to represent a desirable output.

  4. The number of dialysis devices is measured at federal state level.

  5. Specifically, we determine the standard deviation within each district across count statistics for five medical specialists groups (internists, ophthalmologists, orthopaedists, psychotherapists per 100,000 inhabitants, and pediatricians per 100,000 children).

  6. The dependent variable is the log inverted SMR and the explanatory variables are gp, spec, beds, dialysis and speciality diversity in natural logarithms joint with time and district fixed effects.

  7. We construct instruments for the endogenous regressors from their respective lagged first differences. If the error terms are free of serial correlation, these lags will be highly correlated with the endogenous regressors, but uncorrelated with the composite residual process. The lagged instruments range from t − 1 to t − 8. If the assumptions of the Hausman test are met, the IV estimator is consistent, however, OLS is efficient under the null hypothesis of no systematic difference between the estimators [33].

  8. In both IV approaches, the time and district-specific fixed effects are considered as exogenous.

  9. We additionally tested for instrument validity by means of a Sargan Test [63]. The test returned p values of 0.147 (IV1) and 0.159 (IV2). Therefore, we conclude that the instruments fulfill the exogeneity condition.

  10. All estimation results are obtained via full Bayesian MCMC simulations based on 120,000 iterations, a burn-in period of 20,000 iterations and a thinning parameter of 100, resulting in 1000 samples from the posterior. Convergence of the Markov chains are ensured by eyeball inspection. Accordingly, we did not find any evidence for remaining autocorrelation in the sampling paths.

  11. Both model selection criteria can be determined from the MCMC output. Unlike the DIC, the WAIC evaluates the entire posterior distribution, and, hence, might preferred if the posterior distribution lacks normality.

  12. For descriptions of Bayesian R2 and the determination of quantile residuals see Appendix 1.6 and 1.5, respectively.

  13. For instance, for the care of back pain, Andersohn and Walker [3] show that the number of conducted operations varies significantly across regions with an increased number of surgical interventions in areas with medical centres specialised on back problems in Germany.

  14. We further included the dummy variable east to account for differences between Eastern and Western Germany. However, the effect of this variable lacks statistical significance.

  15. It is worth recalling that Germany comprises 402 districts for which we allow spatial dependence patterns. However, we excluded nineteen districts due to data inconsistencies and missing values. By means of the Markov random field (structured spatial effect), we obtain an effect for all 402 districts in Germany while the unstructured (random) spatial contributions are only estimated for regions with at least one observation. In consequence, the estimated spatial effects should be viewed with caution for the districts with no observation.

  16. We evaluate efficiency scores for each district \(i\) in time \(t\) by the mean of the posterior distribution of technical efficiencies as \({\mathbb{E}}\left[ {{ \exp }\left( { - u_{it} |e_{it} } \right)} \right]\), where \(e_{it}\) is the composite error term \(e_{it} = y_{it} + u_{it}\) in (1) [38]. We refer to Klein et al. [40] for the derivation of \(p\left( {u_{it} |e_{it} } \right)\) in the Bayesian framework.

  17. To control for spatial spillover effects, we run a weighted least squares regression of the predicted efficiency scores on an intercept and a rural-urban dummy variable, and account for spatially correlated observations by using an adjacency matrix \(\varvec{A}\) as variance-weighting matrix (see Appendix 1). We evaluate differences in the predicted efficiency scores between urban and rural districts by means of a significance test for the aforementioned dummy variable.

  18. The marginal effects of the regional characteristics on inefficiency directly translate into effects on health as \(\partial \left( {{\mathbb{E}}\left[ {logy_{it} } \right]} \right)/\partial z^{d} = - \partial \left( {{\mathbb{E}}\left[ {u_{it} } \right]} \right)/\partial z^{d}\), where \(z^{d}\) is the \(d\)-th variable in \(z_{it}\) in (4) [68].

  19. A usual form to regularise is \(\lambda \varvec{\zeta 'K\zeta }\) [21].

  20. For a detailed description of Bayesian P-splines, see Lang and Brezger [46], Brezger et al. [7].

  21. Nevertheless, Fahrmeir and Lang [22] showed, that one can only achieve a clear separation of the structured and unstructured part of the spatial effect if one effect dominates the other.

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Acknowledgements

Financial support by the German Research Association (DFG) Research Training Group 1644 ‘Scaling problems in Statistics’, Grant no. 152112243, is gratefully acknowledged. Helpful comments from two anonymous referees are also gratefully acknowledged.

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Appendices

Appendix

The following appendices provide further details on the Bayesian estimation procedure and the derivation of the marginal effects of the \(z\) variables.

The Bayesian stochastic frontier model

Prior specification

In a fully Bayesian approach, the general form of a normal regularisation-type prior with penalisation term and smoothing variance for a vector of unknown regression coefficients \({\varvec{\upzeta}}\) is given by:

$$\begin{array}{*{20}r} \hfill {p(\varvec{\zeta}|\tau^{2} ) \propto \left( {\frac{1}{{\tau^{2} }}} \right)^{{\frac{{rk\left( \varvec{K} \right)}}{2}}} \exp \left\{ { - \frac{1}{{2\tau^{2} }}\varvec{\zeta^{\prime}K\zeta }} \right\}} \\ \end{array}$$
(6)

In (6), \(\varvec{K}\) is a known penalty matrix which is chosen a priori and the smoothing variance is \(\tau^{2} = 1/\lambda\) where \(\lambda \ge 0\) is an unknown smoothing component that determines the strength of the regularisation to avoid overfitting.Footnote 19 To obtain a data-driven degree of smoothness, we assign an inverse gamma hyperprior to \(\tau^{2}\), i.e., \(\tau^{2} \sim IG\left( {a,b} \right)\) with \(a = b = 0.001\), which is the common choice in Bayesian estimation [21]. In summary, the general form of (6) offers a practical and flexible way to deal with any unknown regression coefficients by an adequate choice of \(\varvec{K}\).

Linear and nonlinear effects

In (1) and (4) the coefficient \(\varvec{\beta}\) and \(\varvec{\delta}\) describe the linear influences of the covariate vectors \(x_{it}\) and \(z_{it}\), respectively. For estimation purpose, we replace the variance components of \(u_{it}^{*}\) and \(v_{it}\) by \(\sigma_{u}^{2} = { \exp }\left\{ {c_{u} } \right\}\) and \(\sigma_{v}^{2} = { \exp }\left\{ {c_{v} } \right\}\), respectively, where \(c_{u}\)and \(c_{v}\) are coefficients to be estimated. We restrict (6) with \(\varvec{K} = 0\) to obtain completely non-informative priors. Therefore, the joint prior distributions for \(\beta\), \(\delta\), \(c_{u}\), \(c_{v}\) and \(\mu\) are flat, i.e. \(p\left( \beta \right)\), \(p\left( \delta \right)\), \(p\left( {c_{u} } \right)\), \(p\left( {c_{v} } \right)\), \(p\left( \mu \right) \propto const\).

We model the nonlinear effect of a covariate \(\tilde{x}_{it}\) by means of a smooth function \(f\left( {\tilde{x}_{it} } \right)\). We apply P-splines as introduced by Eilers and Marx [20], and approximate the unknown function by a polynomial spline of degree 3 with 20 equidistantly spaced knots over the domain of \(\tilde{x}_{it}\): \(f\left( {\tilde{x}_{it} } \right) = \varvec{W\tilde{\beta }}\), where \(\varvec{W}\) is the design matrix comprising the basis functions at the observed covariate values and \(\tilde{\varvec{\beta }}\) is a vector of regression coefficients to be estimated. Following Eilers and Marx [20] and Belitz et al. [6], for \(\varvec{\zeta}= \tilde{\varvec{\beta }}\) in (6) the matrix \(\varvec{K}\) comprises a second-order random walk penalty term to obtain a regularised function \(f\left( {\tilde{x}_{it} } \right)\).Footnote 20

Spatial components

To model spatial dependencies, we consider structured spatial effects in the production function (\(\gamma_{i}\)) and in the scaling function (\(\theta_{i}\)). We assign a Markov random field prior to the joint distribution of \(\varvec{\gamma}\) and \(\varvec{\theta}\) [22]. To obtain the representation in (6) for \(\varvec{\zeta}=\varvec{\gamma}\) and \(\varvec{\zeta}=\varvec{\theta}\), respectively, we define a first-order neighbourhood structure on the set of German districts. Thus, the we set \(\varvec{K}\) equal to an adjacency matrix \(\varvec{A}\), which takes the form of an indicator matrix, where the off-diagonal elements are equal to unity if two districts share a common border, and zero otherwise.

As the district-specific effects \(\alpha_{i}\) are independent of the neighbourhood structure in \(\varvec{A}\), one can interpret them as structured spatial effects. In that way, the joint prior distribution of \(\varvec{\alpha}\) corresponds to a Markov random field without neighbourhood structure. We specify the distribution in (6) for \(\varvec{\zeta}=\varvec{\alpha}\) by setting \(\varvec{K}\) equal to an identity matrix \(\varvec{I}\). In summary, the decomposition into structured and unstructured spatial components allows for additional flexibility in the model to recover more general spatial dependencies.Footnote 21

Estimation

The MCMC estimation algorithm is implemented in a developer version of the freely available software BayesX [6, 40] provide a detailed description of thse sampling algorithms which we adopt. Bayesian inference is based on the posterior density functions of the model given by \(p\left( {\zeta |y} \right) \propto p\left( {y|\zeta } \right)p\left( \zeta \right)\), which are obtained from the sampling paths to easily draw inferential results. For simplicity, \(\zeta\) denotes the collection of all unknown model parameters, and \(p\left( \zeta \right)\) are the respective prior distributions which are all of the type of (6), but differ from each other due to the different specifications of \(\varvec{K}\).

Quantile residuals

See Fig. 5,

Fig. 5
figure 5

QQ-Plots. The figures show the standarised quantile residuals of the Models 0-III

Since SFA’s fit into the class of distributional regression models, quantile residuals are commonly used to check if the model has been correctly specified [41]. Quantile residuals are defined as \(\hat{r}_{i} = {\varvec{\Phi}}^{ - 1} ( {F( {y_{i} \left| {\hat{\varvec{\vartheta }}_{i} } \right.} )} )\), with the inverse cumulative distribution function (c.d.f.) of a standard normal distribution \(\varPhi^{ - 1}\) and \(F\left( {. |\hat{\varvec{\vartheta }}} \right)\) denoting the c.d.f. with model specific parameters, i.e., \(\hat{\varvec{\vartheta }}_{0} = \left( {\varvec{\alpha}, \varvec{\beta}, \tilde{\varvec{\beta }}_{1} , \ldots , \tilde{\varvec{\beta }}_{\varvec{J}} ,\varvec{\delta}, \sigma_{v}^{2} , \sigma_{{u^{*} }}^{2} , \mu } \right)^{\prime }\), \(\hat{\vartheta }_{I} = \left( {\varvec{\alpha}, \varvec{\beta}, \tilde{\varvec{\beta }}_{1} , \ldots ,\tilde{\varvec{\beta }}_{\varvec{J}} ,\varvec{ \delta },\varvec{\gamma}, \sigma_{v}^{2} , \sigma_{{u^{*} }}^{2} , \mu } \right)^{\prime } , \hat{\vartheta }_{II} = \left( {\varvec{\alpha}, \varvec{\beta}, \tilde{\varvec{\beta }}_{1} , \ldots ,\tilde{\varvec{\beta }}_{\varvec{J}} ,\varvec{ \delta },\varvec{\theta},\sigma_{v}^{2} , \sigma_{{u^{*} }}^{2} , \mu } \right)^{\prime } , \hat{\vartheta }_{II} = \left( {\varvec{\alpha}, \varvec{\beta}, \tilde{\varvec{\beta }}_{1} , \ldots , \tilde{\varvec{\beta }}_{\varvec{J}} ,\varvec{ \delta },\varvec{\theta},\sigma_{v}^{2} , \sigma_{{u^{*} }}^{2} , \mu } \right)^{\prime } ,\) where the indices are used to distinguish the model specifications ‘0′ to ‘III’ as outlined in Sect. 3.2.1. Based on the SFA specification, \(F\left( {. |\hat{\vartheta }} \right)\) is a mixed normal-half normal distribution [44]. According to Dunn and Smyth [18], the quantile residuals should at least approximately be standard normally distributed if the correct model has been specified. In practice, the residuals can be subjected to eyeball inspection in terms of QQ-plots.

Bayesian R2

In Bayesian inference one obtains a set of posterior simulation draws \(l = 1, \ldots , L\). For each draw, one obtains the vector of predicted values \(\hat{\varvec{y}}^{\left( l \right)}\) and residuals \(\varvec{e}^{\left( l \right)} = \varvec{y} - \hat{\varvec{y}}^{\left( l \right)}\) over all cross-sectional \(i = 1, \ldots , N\) and time instances \(t = 1, \ldots , T\). For each posterior draw \(l\), we calculate the proportion of variance explained as:

$${\text{Bayesian }}R^{2} = \frac{{\frac{1}{NT}\mathop \sum \nolimits_{i = 1}^{N} \mathop \sum \nolimits_{i = 1}^{T} \left( {\hat{y}_{it}^{\left( l \right)} - \hat{y}^{\left( l \right)} } \right)^{2} }}{{\frac{1}{NT}\mathop \sum \nolimits_{i = 1}^{N} \mathop \sum \nolimits_{i = 1}^{T} \left( {\hat{y}_{it}^{\left( l \right)} - \hat{y}^{\left( l \right)} } \right)^{2} + \frac{1}{NT}\mathop \sum \nolimits_{i = 1}^{N} \mathop \sum \nolimits_{i = 1}^{T} \left( {\hat{e}_{it}^{\left( l \right)} - \hat{e}^{\left( l \right)} } \right)^{2} }}$$

Since an R2l obtains for each posterior draw l = 1,…, L, we summarise this sample information by its posterior mean. The Bayesian R2 can be interpreted as a data-based estimate of the proportion of variance explained by the model [27, 28].

Marginal effects

In (4), the scaling function \(h_{it} = { \exp }\left\{ {z_{it}^{'} \delta + \theta_{i} } \right\}\) translates the effects of \(z_{it}\), denoted by \(\delta\), to both the mean and the variance of \(u_{it}^{*}\). The parametrisation of \(u_{it} = h_{it} u_{it}^{*}\) with \(u_{it}^{*} \sim N^{ + } \left( {\mu ,\sigma^{2} } \right)\) is equivalent to \(u_{it} \sim N^{ + } (\mu_{it}^{*} ,\left( {\sigma_{it}^{2} )^{*} } \right)\) where \(\mu_{it}^{*} = \mu { \exp }\left\{ {z_{it}^{'} \delta + \theta_{i} } \right\}\) and \((\sigma_{it}^{2} )^{*} = \sigma^{2} { \exp }\left\{ {2z_{it}^{'} \delta + 2\theta_{i} } \right\}.\) According to Wang [68], the first two moments of \(u_{it}\)read as

$$\begin{aligned} {\mathbb{E}}\left[ {u_{it} } \right] &= \sigma_{it}^{*} \left[ {a + \frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right] \hfill \\ Var\left[ {u_{it} } \right] &= (\sigma_{it}^{2} )^{*} \left[ {1 - a\left[ {\frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right] - \left[ {\frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right]^{2} } \right], \hfill \\ \end{aligned}$$

where \(a = \frac{{\mu_{it}^{*} }}{{\sigma_{it}^{*} }}\) and \(\varphi ( \cdot )\) and \(\varPhi \left( \cdot \right)\) denote the probability density function and the cumulative

density function of the standard normal distribution, respectively. Then, the marginal effect of a change in the \(d\)-th variable in \(z_{it}\) on the respective moments of \(u_{it}\) is given by the partial first derivatives:

$$\begin{aligned} &\begin{aligned}\frac{{\partial {\mathbb{E}}\left[ {u_{it} } \right]}}{{\partial z^{d} }} & = \delta^{d} \left[ {1 - a\left[ {\frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right] - \left[ {\frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right]^{2} } \right] + 2\delta^{d} \sigma_{it}^{*} \\&\quad\times\left[ {\left( {1 + a^{2} } \right)\left[ {\frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right] - \left[ {\frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right]^{2} } \right]\end{aligned} \\& \begin{aligned}\frac{{\partial Var\left[ {u_{it} } \right]}}{{\partial z^{d} }} & = \frac{{\delta^{d} }}{{\sigma_{it}^{*} }}\left[ {\frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right]\left( {\left( {{\mathbb{E}}\left[ {u_{it} } \right]^{2} } \right)\left( {{\mathbb{E}}\left[ {u_{it} } \right]^{2} - Var\left[ {u_{it} } \right]} \right)} \right) \\ & \quad + 2\delta^{d} (\sigma_{it}^{2} )^{*} \left\{ {1 - \frac{1}{2}\left[ {\frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right]\left( {a + a^{3}}\right.}\right.\\&\quad\left.{\left.{ + \left( {2 + 3a^{2} } \right)\left[ {\frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right] + 2a\left[ {\frac{\phi \left( a \right)}{\varPhi \left( a \right)}} \right]^{2} } \right)} \right\}, \\\end{aligned} \end{aligned}$$

where \(\delta^{d}\) is the coefficient of the \(d\)-th variable in \(\delta\).

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Haschka, R.E., Schley, K. & Herwartz, H. Provision of health care services and regional diversity in Germany: insights from a Bayesian health frontier analysis with spatial dependencies. Eur J Health Econ 21, 55–71 (2020). https://doi.org/10.1007/s10198-019-01111-9

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