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Survival after laparoscopic radical surgery for stage IA–IIB cervical cancer: 1316 consecutive cases from a national laparoscopic training center in China

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Abstract

Background

To investigate the survival of cervical cancer patients undergoing laparoscopic radical hysterectomy (LRH) in a minimally invasive gynecology center.

Methods

A consecutive series of patients undergoing first LRH for cervical cancer from May 2008 to December 2017 at a national laparoscopic training center was retrospectively analyzed. The overall survival (OS) and progression-free survival (PFS) were compared between groups.

Results

In total, 1316 women with FIGO (2009) stage IA–IIB cervical cancer received LRH. Among them, 1114 (84.7%) were followed up for 3 months or longer; the median follow-up period was 48 months (range 3–144 months). In patients with stage IA, IB1 (≤ 2 cm), IB1 (> 2 cm), IB2, IIA1 and IIA2-IIB tumors, the 4-year PFS rates were 98.6, 94.5, 87.4, 65.6, 80.0 and 67.4%, respectively, and the 4-year OS rates were 98.6, 96.8, 91.1, 77.4, 85.6 and 76.2%, respectively. The 4-year PFS and OS were as high as 96.2 and 97.5%, respectively, in patients with squamous cell carcinoma of 2 cm or smaller in diameter. A stable high 4-year OS and PFS was achieved after completing 100 LRHs. In patients operated on by the same surgeon, an improvement in survival was observed after 40 LRHs.

Conclusion

Favorable oncologic outcomes can be achieved in patients with IA-IB1 cervical cancer after LRH in a center with a high surgery volume.

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Data availability

The data used to support the findings of this study are available from the corresponding author upon request.

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Funding

This study was supported by the National Natural Science Foundation of China (81974413).

Author information

Author notes

  1. Yuhui Huang and Jing Cai contributed equally to this work.

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China

    Yuhui Huang, Jing Cai, Hongbo Wang, Weihong Dong, Yuan Zhang, Shaohai Wang, Xiaoqi He, Jianfeng Guo, Shouhua Yang & Zehua Wang

Authors
  1. Yuhui Huang
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  2. Jing Cai
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  3. Hongbo Wang
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  4. Weihong Dong
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  5. Yuan Zhang
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  6. Shaohai Wang
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  7. Xiaoqi He
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  8. Jianfeng Guo
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  9. Shouhua Yang
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  10. Zehua Wang
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Corresponding author

Correspondence to Zehua Wang.

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Conflict of interest

The authors declare no conflicts of interests in this work.

Ethical approval and consent to participate

This study was approved by the Ethics Committee of the Tongji Medical College, Huazhong University of Science and Technology (No. 2020S246).

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Huang, Y., Cai, J., Wang, H. et al. Survival after laparoscopic radical surgery for stage IA–IIB cervical cancer: 1316 consecutive cases from a national laparoscopic training center in China. Int J Clin Oncol 28, 175–183 (2023). https://doi.org/10.1007/s10147-022-02262-1

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  • DOI: https://doi.org/10.1007/s10147-022-02262-1

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