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Double-session micropulse transscleral laser (CYCLO G6) for the treatment of glaucoma

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Abstract

This study aims to evaluate the effectiveness and safety of double-session micropulse transscleral (MP3) laser for the treatment of glaucoma. This was a retrospective chart review of all patients who underwent MP3 laser with the standard protocol and were within at least 12 months of their follow-up appointments. Eyes were treated at 2000 mW with 31.3% duty cycle for 80 s per treatment session, with double sessions in each hemifield alternating between upper and lower and upper and lower. Success criterion was defined as a greater than 20% reduction in intraocular pressure (IOP) and an IOP between 6 and 18 mmHg at the end of the follow-up period. Eighty-nine eyes of seventy-six glaucoma patients were included; 31 of which were considered primary, i.e., no previous glaucoma surgery. The average pre-treatment IOP was 29.9 ± 6.4 mmHg. At around 16.7 ± 3.1 months of follow-up, the average IOP was 14.8 ± 4.7 mmHg (p < 0.001) (28.8 ± 7.4 to 15.7 ± 5.3 mmHg, p < 0.001, at 17.0 ± 3.1 months in the primary eyes). The number of topical glaucoma medications was reduced from 3.6 ± 0.5 to 1.9 ± 0.9 at the last evaluation (p < 0.001). The best corrected visual acuity in logMAR ranged from 0.41 ± 0.34 preoperatively to 0.45 ± 0.44 at the last visit (p = 0.2), and also remained stable in primary eyes. Success was obtained in 86.5% of the eyes, with 1.5 ± 0.8 procedures, and in 90.3% with 1.2 ± 0.5 MP3 laser procedures in the primary eye group. MP3 laser in two consecutive 80-s sessions was shown to be safe and effective in the treatment of glaucoma. Primary eyes required lower number of MP3 laser procedures.

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Acknowledgments

The authors would like to thank Isabela Piza Danielsen for important contribution in the manuscript revision.

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Authors and Affiliations

  1. Ophthalmology Department, Federal University of Goiás (CEROF-HC-UFG), Avenida Americano do Brasil, 260, Setor Marista, Goiânia, GO, 74180-010, Brazil

    Leopoldo Magacho, Francisco E. Lima & Marcos P. Ávila

  2. Hospital VER-Excelência em Oftalmologia, Goiânia, GO, Brazil

    Leopoldo Magacho

  3. Centro Brasileiro de Cirurgia de Olhos (CBCO), Goiânia, GO, Brazil

    Francisco E. Lima & Marcos P. Ávila

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  1. Leopoldo Magacho
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  2. Francisco E. Lima
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Correspondence to Leopoldo Magacho.

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The study was conducted after approval by the Ethics Committee of both institutions. The study followed the tenets of the Declaration of Helsinki.

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For this type of study, retrospective chart review, informed consent is not required.

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Magacho, L., Lima, F.E. & Ávila, M.P. Double-session micropulse transscleral laser (CYCLO G6) for the treatment of glaucoma. Lasers Med Sci 35, 1469–1475 (2020). https://doi.org/10.1007/s10103-019-02922-1

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  • DOI: https://doi.org/10.1007/s10103-019-02922-1

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