Abstract
The optimal method for surveillance of carbapenem-resistant Acinetobacter spp. (CRAB) is unknown. A collection of CRAB strains (n = 42), carbapenem-susceptible strains (CSAB), and non-Acinetobacter strains (n = 18) was used to evaluate six laboratory surveillance methods: MacConkey (MAC), MAC + 1 μg/ml imipenem (MAC-IPM), minimal salts agar + 1 % acetate (MSA), MSA with IPM disk (MSA-IPM), CHROMagarKPC, and CHROMagar Acinetobacter with CR102 (CHROMAcineto). CHROMAcineto was 100 % sensitive and specific. CHROMagarKPC and MAC-IPM were highly sensitive (>95 %), but their specificity was substantially hampered by the breakthrough growth of CSAB. MSA was unsuitable for CRAB detection. CHROMAcineto is a promising medium for CRAB detection and warrants further clinical evaluation.
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Moran-Gilad, J., Adler, A., Schwartz, D. et al. Laboratory evaluation of different agar media for isolation of carbapenem-resistant Acinetobacter spp.. Eur J Clin Microbiol Infect Dis 33, 1909–1913 (2014). https://doi.org/10.1007/s10096-014-2159-y
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DOI: https://doi.org/10.1007/s10096-014-2159-y