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Prevalence and the age of onset patterns of stroke in Jiangsu Province, China

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Abstract

Objectives

Little was known regarding the current age of onset patterns of stroke. This study aimed to examine the prevalence of stroke and explore the age of onset patterns of stroke in Jiangsu Province, China.

Materials and methods

Participants were recruited from April 2012 to April 2013 in Jiangsu Province, China. Survival analysis models were used to evaluate the hazards of stroke by a single year of age. Kaplan–Meier analysis and the log-rank test were used to explore the disparities of the age of onset patterns of stroke.

Results

This population-based study was conducted among 39,887 participants aged ≥ 18 years in Jiangsu Province, China. Of the 740 (1.9%) events of stroke, 13.2% suffered from hemorrhagic stroke (HS) and 86.8% suffered from ischemic stroke (IS). The prevalence of HS and IS were 0.3% and 1.7%, respectively. The estimated mean age of onset of stroke was 71.98 (95% CI: 71.97–71.99) years by the survival model. Up to age of 45 years, the estimated hazards of stroke onset were at a relatively low level. From the age of 45 years, the increases in hazards accelerated and peaked at age 75 years. Urban, smoking, and drinking males had a higher risk of stroke than their counterparts (P < 0.05). However, no such difference was found among females.

Conclusions

The findings emphasize the importance of implementing stroke prevention interventions in Jiangsu Province, China, especially for urban, smoking, and drinking males. It is of great significance to strengthen comprehensive management of health-related behaviors, including smoking cessation and moderate consumption of alcohol to have sustained beneficial effects on stroke risk.

Chenlu He and Qian Chen contributed equally to this work.

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Data availability

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

The authors would like to thank all the participants involved in the survey.

Funding

This work was supported by the National Natural Science Foundation of China [82003484], Natural Science Fund for Colleges and Universities in Jiangsu Province [20KJB330005], General project of philosophy and social science researches for colleges and universities in Jiangsu Province [2020SJA1053], and Jiangsu Province Postdoctoral Science Foundation [2020Z177].

Author information

Authors and Affiliations

  1. School of Public Health, Xuzhou Medical University, 209 Tong Shan Road, Xuzhou, 221004, Jiangsu, China

    Chenlu He, Qian Chen, Ziyuan Shen, Ying Zhang, Hao Hou, Yifei Pei, Wei Wang & Xunbao Zhang

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  1. Chenlu He
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Contributions

Conceptualization, methodology: Wei Wang, Xunbao Zhang; Data curation, writing—original draft preparation: Chenlu He, Qian Chen, Ziyuan Shen; Supervision, validation: Ying Zhang, Hao Hou, Yifei Pei; Writing—reviewing and editing: Wei Wang.

Corresponding authors

Correspondence to Wei Wang or Xunbao Zhang.

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Ethics approval and consent to participate

Approval was obtained from the ethics committee of Xuzhou Medical University. The procedures used in this study adhere to the tenets of the Declaration of Helsinki. All participants gave their written informed consent before their inclusion in the study.

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The authors declare no competing interests.

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Cite this article

He, C., Chen, Q., Shen, Z. et al. Prevalence and the age of onset patterns of stroke in Jiangsu Province, China. Neurol Sci 44, 215–227 (2023). https://doi.org/10.1007/s10072-022-06428-7

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