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Neurological manifestations of neurofibromatosis: a review

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Abstract

Neurofibromatosis type 1(NF1) is a dominantly inherited genetic disorder caused by a mutation in the NF1 tumor-suppressor gene. Patients are prone to develop benign and malignant tumors not only in the central and peripheral nervous system but also in other parts of the body. Apart from tumors, neurofibromatosis may also be associated with neurological symptoms and disorders such as cerebrovascular disease, epilepsy, neuropathy, and headache. This article seeks to review the different neurological manifestations of neurofibromatosis.

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Authors and Affiliations

  1. Department of Neurology & Centre for Rare Diseases, Aarhus University Hospital, Aarhus, Denmark

    Michael Bayat

  2. Danish Epilepsy Centre, Dianalund, Denmark

    Allan Bayat

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  1. Michael Bayat
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Bayat, M., Bayat, A. Neurological manifestations of neurofibromatosis: a review. Neurol Sci 41, 2685–2690 (2020). https://doi.org/10.1007/s10072-020-04400-x

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