Abstract
Standard guidelines for ongoing management, as well as definitive data about the long-term course of idiopathic intracranial hypertension (IIH) are not available. The aim of this study was to compare several clinical and instrumental variables as assessed at the time of diagnosis and then after 1 year in a sample of IIH patients. A total of 21 patients were studied. Our results confirmed that headache and TVO are the most frequent symptoms in IIH patients, and that overweight is a very common feature. A trend towards a favorable outcome in patients followed for 1 year and treated by usual medical therapy was found: intracranial pressure was lower at follow-up; improvement of headache and transient visual obscurations, as well as of papilledema, was reported in most patients. On the other hand, neuroradiological findings (such as empty sella, perioptic subarachnoid space distension, narrowing of the transverse sinuses) were substantially stable at follow. These findings may be relevant for future research as far as understanding the role of different clinical and instrumental findings as diagnostic items as well as predictors of outcome in IIH.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Headache Classification Subcommittee of the International Headache Society (2004) International classification of headache disorders, 2nd edition. Cephalalgia 24:1–160
Fraser C, Plant GT (2011) The syndrome of pseudotumor cerebri and idiopathic intracranial hypertension. Curr Opin Neurol 24:12
Friedman DI, Liu GT, Digre KB (2013) Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children. Neurology 81(13):1159–1165
Yuh WT, Zhu M, Taoka T et al (2000) MR imaging of pituitary morphology in idiopathic intracranial hypertension. J Magn Reson Imaging 12:808–813
Farb RI, Vanek I, Scott JN, Mikulis DJ, Willinsky RA, Tomlinson G, Brugge KG (2003) Idiopathic intracranial hypertension: the prevalence and morphology of sinovenous stenosis. Neurology 60(9):1418–1424
Hoffman J, Huppertz H-J, Scmidt C et al (2013) Morphometric and volumetric MRI changes in idiopathic intracranial hypertension. Cephalalgia 33(13):1075–1084
D’Amico D, Curone M, Ciasca P, Cammarata G, Melzi L, Bussone G, Bianchi Marzoli S (2013) Headache prevalence and clinical features in patients with idiopathic intracranial Hypertension (IIH). Neurol Sci 34(Suppl 1):S147–S149
Skau M, Sander B, Milea D, Jensen R (2011) Disease activity in idiopathic intracranial hypertension: a 3-month follow-up study. J Neurol 258(2):277–283
Ball AK, Howman A, Wheatley K, Burdon MA, Matthews T, Jacks AS, Lawden M, Sivaguru A, Furmston A, Howell S, Sharrack B, Davies MB, Sinclair AJ, Clarke CE (2011) A randomised controlled trial of treatment for idiopathic intracranial hypertension. J Neurol 258(5):874–878
Riggeal BD, Bruce BB, Saindane AM, Ridha MA, Kelly LP, Newman NJ, Biousse V (2013) Clinical course of idiopathic intracranial hypertension with transverse sinus stenosis. Neurology 80(3):289–295
Digre KB (2013) Imaging characteristics of IIH: are they reliable? Cephalalgia 33(13):1067
De Simone R, Ranieri A, Bonavita V (2010) Advancement in idiopathic intracranial hypertension pathogenesis: focus on sinus venous stenosis. Neurol Sci 31(Suppl 1):S33–S39
Conflict of interest
D. D’Amico certifies that there is no actual or potential conflict of interest in relation to this article.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
D’Amico, D., Curone, M., Erbetta, A. et al. Intracranial idiopathic hypertension: 1-year follow-up study. Neurol Sci 35 (Suppl 1), 177–179 (2014). https://doi.org/10.1007/s10072-014-1765-x
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10072-014-1765-x