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A review on regulatory aspects, challenges and public perception in acceptance of genetically modified foods

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Abstract

A clear vision for the future of the world’s food supply must be developed by all stakeholders, including consumers, farmers, and governments, especially in light of the rapid improvements in the production of genetically modified crops. It has been possible through biotechnology and genetic engineering, genetically modified (GM) crops have been engineered to have certain qualities, such as resistance to pests, illnesses, or herbicides. Concerns about risks and unintended effects of GM crops include ecosystem impacts, new pests or diseases, and health effects on humans and animals. There is mounting evidence that consumers may respond unfavourably to the introduction of genetically altered foods. This research focuses at how genetic engineering can raise agricultural yields, improve nutrient content, and lessen the use for hazardous pesticides and herbicides in food production. Regulatory framework for GM foods may impact on perception and acceptance of consumers.

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References

  • Afzal M, Hindawi SES, Alghamdi SS, Migdadi HH, Khan MA, Hasnain MU, Arslan M, Habib UR, Rahman M, and Sohaib M. Potential breeding strategies for improving salt tolerance in crop plants. Journal of Plant Growth Regulation. 42: 3365-3387 (2023)

    Article  CAS  Google Scholar 

  • Alvarez S, Rohrig E, Solís D, Thomas MH. Citrus greening disease (huanglongbing) in florida: economic impact, management and the potential for biological control. Agricultural Research. 5: 109-118 (2016)

    Article  CAS  Google Scholar 

  • Amna Qamar S, Tantray AY, Bashir SS, Zaid A, Wani SH. Golden rice: genetic engineering, promises, present status and future prospects. Rice Research for Quality Improvement: Genomics and Genetic Engineering. pp. 581-604 (2020)

    Google Scholar 

  • Anderson JA, Ellsworth PC, Faria JC, Head GP, Owen MD, Pilcher CD, Shelton AM, Meissle M. Genetically engineered crops: Importance of diversified integrated pest management for agricultural sustainability. Frontiers in Bioengineering and Biotechnology. 7: 24 (2019)

    Article  PubMed  PubMed Central  Google Scholar 

  • Ben Mrid R, Benmrid B, Hafsa J, Boukcim H, Sobeh M, Yasri A. Secondary metabolites as biostimulant and bioprotectant agents: a review. Science of the Total Environment. 777: 146204 (2021)

    Article  CAS  ADS  Google Scholar 

  • Berchembrock YV, Pathak B, Maurya C, Botelho FBS, Srivastava V. Phenotypic and transcriptomic analysis reveals early stress responses in transgenic rice expressing Arabidopsis DREB1a. Plant Direct. 6: e456 (2022)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bhatia L, Jha H, Sarkar T, Sarangi PK. Food waste utilization for reducing carbon footprints towards sustainable and cleaner environment: a review. International Journal of Environmental Research and Public Health. 20: 2318 (2023)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Boccia F, Punzo G. A choice experiment on consumer perceptions of three generations of genetically modified foods. Appetite. 161: 105158 (2021)

    Article  PubMed  Google Scholar 

  • Bošković J, Žuža M. Impact of genetically modified plants on the environment. In Technology and Engineering Management. 2: 294-311 (2019)

    Google Scholar 

  • Boukar O, Abberton M, Oyatomi O, Togola A, Tripathi L, Fatokun C. Introgression breeding in cowpea [Vigna unguiculata (L.) Walp.]. Frontiers in Plant Science. 11: 567425 (2020)

    Article  PubMed  PubMed Central  Google Scholar 

  • Bruetschy C. The EU regulatory framework on genetically modified organisms (GMOs). In Transgenic Research. 28: 169-174 (2019).

    Article  CAS  Google Scholar 

  • Caradus J. Impacts of growing and utilising genetically modified crops and forages–a New Zealand perspective. New Zealand Journal of Agricultural Research. 1-30 (2022)

    Article  Google Scholar 

  • Castera L, Friedrich-Rust M, Loomba R. Noninvasive assessment of liver disease in patients with non-alcoholic fatty liver disease. Gastroenterology. 156: 1264-1281 (2019)

    Article  PubMed  Google Scholar 

  • Chanu NB, Alice AK, Thokchom A, Singh MC, Chanu NT, Singh YD. Engineered nanomaterial and their interactions with plant–soil system: a developmental journey and opposing facts. Nanotechnology for Environmental Engineering. 6: 36 (2021)

    Article  Google Scholar 

  • Chen K, Wang Y, Zhang R, Zhang H, Gao C. CRISPR/Cas Genome Editing and Precision Plant Breeding in Agriculture. Annual Review of Plant Biology. 70: 667-697 (2019)

    Article  CAS  PubMed  Google Scholar 

  • Crotty C, Hannula FE, Hallama SE, Kandeler M. Can soil improving cropping systems reduce the loss of soil biodiversity within agricultural soils. Sustainable Soil Management as a Key to Preserving Soil Biodiversity and Stopping its Degradation. International Union of Soil Sciences. 187-220 (2022)

  • Cuvaca I, Knezevic S, Scott J, Osipitan OA. Growth and yield losses of roundup ready soybean as influenced by micro-rates of 2,4-D. Sustainable Agriculture Research. 10: 1-27 (2021)

    Article  Google Scholar 

  • Ellegaard O, Wallin JA. The bibliometric analysis of scholarly production: How great is the impact?. Scientometrics. 105: 1809-1831 (2015)

    Article  PubMed  PubMed Central  Google Scholar 

  • Fabrick JA, Li X, Carrière Y, Tabashnik BE. Molecular genetic basis of lab- and field-selected Bt resistance in pink bollworm. Insects. 14: 201 (2023)

    Article  PubMed  PubMed Central  Google Scholar 

  • Feldmann F, Jehle J, Bradáčová K, Weinmann M. Biostimulants, soil improvers, bioprotectants: promoters of bio-intensification in plant production. Journal of Plant Diseases and Protection. 129: 707-713 (2022)

    Article  Google Scholar 

  • Fernbach PM, Light N, Scott SE, Inbar Y, Rozin P. Extreme opponents of genetically modified foods know the least but think they know the most. Nature Human Behaviour. 3: 251-256 (2019)

    Article  PubMed  Google Scholar 

  • Gebremichael DE, Haile ZM, Negrini F, Sabbadini S, Capriotti L, Mezzetti B, Baraldi E. RNA interference strategies for future management of plant pathogenic fungi: Prospects and challenges. Plants. 10: 650 (2021)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gizaw Z. Public health risks related to food safety issues in the food market: a systematic literature review. Environmental Health and Preventive Medicine. 24: 68 (2019)

    Article  PubMed  PubMed Central  Google Scholar 

  • Gupta S, Kumar A, Patel R, Kumar V. Genetically modified crop regulations: scope and opportunity using the CRISPR-Cas9 genome editing approach. Molecular Biology Reports. 48: 4851-4863 (2021)

    Article  CAS  PubMed  Google Scholar 

  • Halimah M, Rahmat A, Redjeki S. Use of video modeling examples to improve understanding of the concept of recombinant DNA technology for biology teacher candidates. 060014 (2019)

  • Hanlon P, Sewalt V. GEMs: genetically engineered microorganisms and the regulatory oversight of their uses in modern food production. Critical Reviews in Food Science and Nutrition. 61: 959-970 (2021)

    Article  CAS  PubMed  Google Scholar 

  • Han-Tosunoglu C, Lederman NG. Developing an instrument to assess pedagogical content knowledge for biological socio-scientific issues. Teaching and Teacher Education. 97: 103217 (2021)

    Article  Google Scholar 

  • Hemre Gi, Sanden M, Bakke-Mckellep AM, Sagstad A, Krogdahl A. Growth, feed utilization and health of Atlantic salmon Salmo salar L. fed genetically modified compared to non-modified commercial hybrid soybeans. Aquaculture Nutrition. 11: 157-167 (2005)

    Article  Google Scholar 

  • Hillary VE, Ceasar SA. A Review on the mechanism and applications of crispr/cas9/cas12/cas13/cas14 proteins utilized for genome engineering. Molecular Biotechnology. 65: 311-325 (2023)

    Article  CAS  PubMed  Google Scholar 

  • Jovarauskas D, Steponavičius D, Kemzūraitė A, Zinkevičius R, Venslauskas K. Comparative analysis of the environmental impact of conventional and precision spring wheat fertilization under various meteorological conditions. Journal of Environmental Management. 296: 113150 (2021)

    Article  CAS  PubMed  Google Scholar 

  • Kavhiza NJ, Zargar M, Prikhodko SI, Pakina EN, Murtazova KMS, Nakhaev MR. Improving crop productivity and ensuring food security through the adoption of genetically modified crops in sub-Saharan Africa. Agronomy. 12: 439 (2022)

    Article  CAS  Google Scholar 

  • Khalid W, Ali A, Arshad MS, Afzal F, Akram R, Siddeeg A, Kousar S, Rahim MA, Aziz A, Maqbool Z, Saeed A. Nutrients and bioactive compounds of Sorghum bicolor L. used to prepare functional foods: a review on the efficacy against different chronic disorders. International Journal of Food Properties. 25: 1045-1062 (2022)

    Article  Google Scholar 

  • Kiranmai C, Pullaiah T, Rajam MV. Genetically modified brinjal (Solanum melongena L.) and beyond. Genetically Modified Crops. 31-52 (2021)

    Article  Google Scholar 

  • Knez M, Ranic M, Gurinovic, M, Glibetic M, Savic J, Mattas K, Yercan M. Causes and conditions for reduced cultivation and consumption of underutilized crops: is there a solution?. Sustainability. 15: 3076 (2023)

    Article  CAS  Google Scholar 

  • Koç E, Karayiğit B. Assessment of biofortification approaches used to improve micronutrient-dense plants that are a sustainable solution to combat hidden hunger. Journal of Soil Science and Plant Nutrition. 22: 475-500 (2022)

    Article  PubMed  Google Scholar 

  • Koshovets OB, Frolov IE. Brave new world: on science transformation into technoscience. Epistemology & Philosophy of Science. 57: 20-31 (2020)

    Article  Google Scholar 

  • Kremer RJ. Impacts of genetically engineered crops on the soil microbiome, biological processes and ecosystem services. GMOs: Implications for Biodiversity Conservation and Ecological Processes. Springer. 129-148 (2020)

    Book  Google Scholar 

  • Kumar H, Srivastava P, Lamba J, Ortiz BV, Way TR, Sangha L, Takhellambam BS, Morata G, Molinari R. Within-field variability in nutrients for site-specific agricultural management in irrigated cornfield. Journal of the ASABE. 65: 865-880 (2022)

    Article  Google Scholar 

  • Kumar K, Gambhir G, Dass A, Tripathi AK, Singh A, Jha AK, Yadava P, Choudhary M, Rakshit S. Genetically modified crops: current status and future prospects. Planta. 251: 91 (2020)

    Article  CAS  PubMed  Google Scholar 

  • Lassoued R, Phillips PW, Macall DM, Hesseln H, Smyth SJ. Expert opinions on the regulation of plant genome editing. Plant Biotechnology Journal. 19: 1104-1109 (2021)

    Article  PubMed  PubMed Central  Google Scholar 

  • Li C, Guo J, Wang D, Chen X, Guan H, Li Y, Zhang D, Liu X, He G, Wang T, Li Y. Genomic insight into changes of root architecture under drought stress in maize. Plant, Cell & Environment. 46: 1860-1872 (2023)

    Article  CAS  Google Scholar 

  • Li T, Yang Y, Qi H, Cui W, Zhang L, Fu X, He X, Liu M, Li P, Yu T. CRISPR/Cas9 therapeutics: progress and prospects. Signal Transduction and Targeted Therapy. 8: 36 (2023)

    Article  PubMed  PubMed Central  Google Scholar 

  • Mallikarjuna MG, Veeraya P, Tomar R, Jha S, Nayaka SC, Lohithaswa HC, Chinnusamy V. Next-generation breeding approaches for stress resilience in cereals: current status and future prospects. In Next-Generation Plant Breeding Approaches for Stress Resilience in Cereal Crops. Springer Nature Singapore. 1-43 (2022)

    Chapter  Google Scholar 

  • McPhetres J, Rutjens BT, Weinstein N, Brisson JA. Modifying attitudes about modified foods: Increased knowledge leads to more positive attitudes. Journal of Environmental Psychology. 64: 21-29 (2019)

    Article  Google Scholar 

  • Mizik T. How can precision farming work on a small scale? A systematic literature review. Precision Agriculture. 24(1): 384-406 (2023)

    Article  Google Scholar 

  • Muddassir Muhammad, Al-Zahrani Khodran Hamdan. General overview: awareness of genetically modified food among consumers. International Journal of Agriculture and Biosciences. 11: 48-52 (2022)

    Article  Google Scholar 

  • Muzhinji N, Ntuli V. Genetically modified organisms and food security in Southern Africa: conundrum and discourse. GM Crops & Food. 12: 25-35 (2021)

    Article  Google Scholar 

  • Naccache JM, Jouneau S, Didier M, Borie R, Cachanado M, Bourdin A, Nunes H. Cyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis (EXAFIP): a randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet Respiratory Medicine. 10: 26-34 (2022)

    Article  CAS  PubMed  Google Scholar 

  • Nawaz MA, Mesnage R, Tsatsakis AM, Golokhvast KS, Yang SH, Antoniou MN, Chung G. Addressing concerns over the fate of DNA derived from genetically modified food in the human body: a review. Food and Chemical Toxicology. 124: 423-430 (2019)

    Article  CAS  PubMed  Google Scholar 

  • Nyika RS, Yadav J, Mackolil SJ, GRP Workie E, Ragupathy R, Ramasundaram P. Genetically modified foods: bibliometric analysis on consumer perception and preference. GM Crops & Food. 13: 65-85 (2022)

    Article  Google Scholar 

  • Omeje CH. Media coverage and framing of genetically modified crops: A case study of science journalism in Nigeria (Doctoral dissertation, Stellenbosch: Stellenbosch University) (2019)

  • Onovo JC, Dashe ES, Onwualu Az, Ezealigo US, George R. Unlocking the future of bioenergy in nigeria using genetic modification framework (GMF) of switchgrass. IOP Conference Series: Earth and Environmental Science. 730: 012003 (2021)

  • Pham N, Mandel N. What influences consumer evaluation of genetically modified foods? Journal of Public Policy & Marketing. 38: 263-279 (2019)

    Article  Google Scholar 

  • Pollak SD, Smith KE. Thinking clearly about biology and childhood adversity: next steps for continued progress. Perspectives on Psychological Science. 16: 1473-1477 (2021)

    Article  PubMed  PubMed Central  Google Scholar 

  • Rahman SU, McCoy E, Raza G, Ali Z, Mansoor S, Amin I. Improvement of soybean; a way forward transition from genetic engineering to new plant breeding technologies. Molecular Biotechnology. 65: 162-180 (2023)

    Article  CAS  PubMed  Google Scholar 

  • Randle M, Tennant P. Transgenic papaya. In Genetically Modified Crops. 129-160 (2021)

    Google Scholar 

  • Richael CM. Development of the genetically modified innate ® potato. Plant Breeding Reviews. 57-78 (2021a)

    Article  Google Scholar 

  • Romeis J, Naranjo SE, Meissle M, Shelton AM. Genetically engineered crops help support conservation biological control. Biological Control. 130: 136-154 (2019)

    Article  Google Scholar 

  • Samuel L, Goodstein L, Basch CH. Online news coverage of infant formula shortage in the United States: a content analysis. Dialogues in Health. 1: 100065 (2022)

    Article  Google Scholar 

  • Sharma P, Singh SP, Iqbal HMN, Parra-Saldivar R, Varjani S, Tong YW. Genetic modifications associated with sustainability aspects for sustainable developments. Bioengineered. 13: 9509–9521 (2022)

    Article  CAS  PubMed Central  Google Scholar 

  • Shrestha S, Fu Y, Michael VN, Meru G. Whole genome re-sequencing and bulk segregant analysis reveals chromosomal location for papaya ringspot virus w resistance in squash. Frontiers in Plant Science. 13 (2022)

    Article  PubMed  PubMed Central  Google Scholar 

  • Shuhart CR, Yeap SS, Anderson PA, Jankowski LG, Lewiecki EM, Morse LR, Shepherd JA. Executive summary of the 2019 ISCD position development conference on monitoring treatment, DXA cross-calibration and least significant change, spinal cord injury, peri-prosthetic and orthopedic bone health, transgender medicine, and pediatrics. Journal of Clinical Densitometry. 22: 453-471 (2019)

    Article  PubMed  Google Scholar 

  • Singh S, Kaur R. Genetically modified food (GMF) and its challenges. Recent Advances in Food Biotechnology. Springer Nature Singapore. 387-400 (2022)

    Book  Google Scholar 

  • Suldovsky B, Akin H. The Role of trust in communicating scientific consensus and the environmental benefits of genetically engineered crops: experimental evidence of a backfire effect. Environmental Communication. 17: 101-118 (2023)

    Article  Google Scholar 

  • Swaminathan S, Hemalatha R, Pandey A, Kassebaum NJ, Laxmaiah A, Longvah T, Dandona L. The burden of child and maternal malnutrition and trends in its indicators in the states of India: the global burden of disease study 1990–2017. The Lancet Child & Adolescent Health. 3: 855-870 (2019)

    Article  Google Scholar 

  • Thomas JR, Martin P, Etnier JL, Silverman SJ. Research methods in physical activity. Human Kinetics. (2022)

    Google Scholar 

  • Toulotte JM, Pantazopoulou CK, Sanclemente MA, Voesenek LA, Sasidharan R. Water stress resilient cereal crops: lessons from wild relatives. Journal of Integrative Plant Biology. (2022)

    Article  PubMed  PubMed Central  Google Scholar 

  • Vega Rodríguez A, Rodríguez-Oramas C, Sanjuán Velázquez E, Hardisson de la Torre A, Rubio Armendáriz C, Carrascosa Iruzubieta C. Myths and realities about genetically modified food: a risk-benefit analysis. Applied Sciences. 12: 2861 (2022)

    Article  Google Scholar 

  • Waltz E. Nonbrowning GM apple cleared for market. Nature Biotechnology. 33: 326-327 (2015)

    Article  CAS  PubMed  Google Scholar 

  • Waterfield G, Kaplan S, Zilberman D. Willingness to pay versus willingness to vote: consumer and voter avoidance of genetically modified foods. American Journal of Agricultural Economics. 102: 505-524 (2020)

    Article  Google Scholar 

  • Yang M, Luo F, Song Y, Ma S, Ma Y, Fazal A, Yin T, Lu G, Sun S, Qi J, Wen Z, Li Y, Yang Y. The host niches of soybean rather than genetic modification or glyphosate application drive the assembly of root‐associated microbial communities. Microbial Biotechnology. 15: 2942-2957 (2022)

    Article  PubMed  PubMed Central  Google Scholar 

  • Yen NTH, Huong NTM, Hoa PN, Van Hung P. Incorporation of germinated mung bean flour with rice flour to enhance physical, nutritional and sensory quality of gluten‐free cookies. International Journal of Food Science & Technology. 58: 423-431 (2023)

    Article  CAS  Google Scholar 

  • Zou W, Lo D, Kochhar PS, Le XBD, Xia X, Feng Y, Xu B. Smart contract development: challenges and opportunities. IEEE Transactions on Software Engineering. 47: 2084-2106 (2019)

    Article  Google Scholar 

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  1. Department of Food Technology and Nutrition, School of Agriculture, Lovely Professional University, Phagwara, Punjab, 144001, India

    A. Kanthi Naveen

  2. Department of Food Processing Technology, Institute of Biosciences and Technology, MGM University, Chatrapati Sambhajinagar, Maharashtra, 431003, India

    Manmath Sontakke

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Naveen, A.K., Sontakke, M. A review on regulatory aspects, challenges and public perception in acceptance of genetically modified foods. Food Sci Biotechnol 33, 791–804 (2024). https://doi.org/10.1007/s10068-023-01481-0

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