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Monitoring arsenic species concentration in rice-based processed products distributed in South Korean markets and related risk assessment

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Abstract

Rice is an important grain as a major source of carbohydrates in Asia but contains more arsenic (As) than other grains. A total of 239 rice-based processed foods (rice, n = 30; rice cake, n = 30; porridge, n = 39; noodles, n = 33; bread, n = 20; snack, n = 59; powder, n = 28) were purchased in 2019 from domestic markets to measure total As (tAs) and As species. The average tAs and inorganic As (iAs) in each sample group ranged from 20 to 180 μg/kg (porridge for baby to noodle) and 4.4–85 μg/kg (porridge for baby to powder), respectively. The correlation between the iAs and tAs was affected by the variety of ingredients, such as the presence of seaweed (tAs) and the milling type of rice (iAs). Although rice cakes and baby rice-based powders are a source of concern for both adults and children, respectively, risk assessments indicate that most rice-based foods are generally safe to consume in South Korea.

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References

  • Alexander J, Benford D, Boobis A, Ceccatelli S, Cravedi J-P, Di Domenico A, Doerge D, Dogliotti E, Edler L, Farmer P. Scientific opinion on arsenic in food EFSA panel on contaminants in the food chain (CONTAM). EFSA Journal. 7: 1-199 (2009)

    Google Scholar 

  • ASTDR. ATSDR’s Substance Priority List. Available from: https://www.atsdr.cdc.gov/spl/. Accessed Oct. 24, 2019

  • Bascuñán KA, Vespa MC, Araya M. Celiac disease: understanding the gluten-free diet. European Journal of Nutrition. 56: 449-459 (2017)

    PubMed  Google Scholar 

  • Bessems JG, Paini A, Gajewska M, Worth A. The margin of internal exposure (MOIE) concept for dermal risk assessment based on oral toxicity data–a case study with caffeine. Toxicology. 392: 119-129 (2017)

    CAS  PubMed  Google Scholar 

  • Brandon EF, Janssen PJ, de Wit-Bos L. Arsenic: bioaccessibility from seaweed and rice, dietary exposure calculations and risk assessment. Food Additives and Contaminants: Part A. 31: 1993-2003 (2014)

    CAS  Google Scholar 

  • Choi H, Park S-K, Kim D-S, Kim M. Determination of 6 arsenic species present in seaweed by solvent extraction, clean-up, and LC-ICP/MS. Food Science and Biotechnology. 20: 39-44 (2011)

    CAS  Google Scholar 

  • Christensen HE, Luginbyhl TT Registry of toxic effects of chemical substances. Tracor JITCO, Inc., Rockville, MD, USA (1975)

    Google Scholar 

  • Cubadda F, Jackson BP, Cottingham KL, Van Horne YO, Kurzius-Spencer M. Human exposure to dietary inorganic arsenic and other arsenic species: State of knowledge, gaps and uncertainties. Science of the Total Environment. 579: 1228-1239 (2017)

    CAS  PubMed  Google Scholar 

  • Demaegdt H, Waegeneers N, Cheyns K, Ruttens A. Does arsenic pose a health concern after consumption of clay products? Food Additives and Contaminants: Part A. 38: 113-124 (2021)

    CAS  Google Scholar 

  • Devesa V, Martinez A, Suner M, Benito V, Velez D, Montoro R. Kinetic study of transformations of arsenic species during heat treatment. Journal of Agricultural and Food Chemistry. 49: 2267-2271 (2001)

    CAS  PubMed  Google Scholar 

  • Fradinho P, Raymundo A, Sousa I, Domínguez H, Torres MD. Edible brown seaweed in gluten-free pasta: Technological and nutritional evaluation. Foods. 8: 622-639 (2019)

    CAS  PubMed  PubMed Central  Google Scholar 

  • Gavilanes-Terán I, Cano-Lamadrid M, Idrovo-Novillo J, García-García E, Veloz-Mayorga N, Erazo-Arrieta R, Burló F, Cruz-Paca F, Carbonell-Barrachina ÁA. Inorganic arsenic content in Ecuadorian rice-based products. Food Additives and Contaminants: Part A. 36: 922-928 (2019)

    Google Scholar 

  • Han J, Gouk S. Analysis on consumers' perceptions and preferred attributes toward the processed rice foods-Focusing on breads, biscuits, noodles. Korean Journal of Food Marketing Economics. 31: 29-47 (2014)

    Google Scholar 

  • Hindmarsh JT, McCurdy RF, Savory J. Clinical and environmental aspects of arsenic toxicity. CRC Critical Reviews in Clinical Laboratory Sciences. 23: 315-347 (1986)

    CAS  PubMed  Google Scholar 

  • Huang Y, Wang M, Mao X, Qian Y, Chen T, Zhang Y. Concentrations of inorganic arsenic in milled rice from China and associated dietary exposure assessment. Journal of Agricultural and Food Chemistry. 63: 10838-10845 (2015)

    CAS  PubMed  Google Scholar 

  • IARC (International Agency for Research on Cancer). Overall evaluations of carcinogenicity: an updating of IARC monographs volumes 1 to 42. World Health Organization, Lyon, France. (1987)

  • IARC (International Agency for Research on Cancer). A Review of Human Carcinogens: Arsenic, Metals, Fibres, and Dusts. IARC Press, Lyon, France. (2012)

  • ICH Harmonised Tripartite Guideline. Validation of Analytical Procedures; Text and Methodology Q2(R1). International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use, Geneva, 1–13 (2005)

  • Islam S, Rahman MM, Rahman MA, Naidu R. Inorganic arsenic in rice and rice-based diets: Health risk assessment. Food Control. 82: 196-202 (2017)

    CAS  Google Scholar 

  • Jackson BP, Taylor VF, Punshon T, Cottingham KL. Arsenic concentration and speciation in infant formulas and first foods. Pure and Applied Chemistry. 84: 215-223 (2012)

    CAS  Google Scholar 

  • Jung MY. Inorganic arsenic contents in infant rice powders and infant rice snacks marketed in Korea determined by a highly sensitive gas chromatography-tandem mass spectrometry following derivatization with British Anti-Lewisite. Food Science and Biotechnology. 27: 617-622 (2018)

    CAS  PubMed  Google Scholar 

  • KFC (Korea Food Code). Arsenic (As). Available from: https://www.foodsafetykorea.go.kr/foodcode/01_03.jsp?idx=12041. Accessed Oct. 26, 2020a

  • KFC (Korea Food Code). Inorganic arsenic. Available from: https://www.foodsafetykorea.go.kr/foodcode/01_03.jsp?idx=12042. Accessed Oct. 26, 2020b

  • Khan N, Ryu KY, Choi JY, Nho EY, Habte G, Choi H, Kim MH, Park KS, Kim KS. Determination of toxic heavy metals and speciation of arsenic in seaweeds from South Korea. Food Chemistry. 169: 464-470 (2015)

    CAS  PubMed  Google Scholar 

  • Kim J, Yoon W, Lee S, Lee J, Goo B. [Food Industry Division, Ministry of Agriculture, Food and Rural Affairs] Basic Study on the Establishment of Basic Plan for the 2nd Rice Processing Industry Promotion and Promotion of Rice Utilization. National Library of Korea linked data. 6: 1-181 (2018)

    Google Scholar 

  • Kim M-H, Kim J, Noh C-H, Choi S, Joo Y-S, Lee K-W. Monitoring Arsenic Species Content in Seaweeds Produced off the Southern Coast of Korea and Its Risk Assessment. Environments. 7 (2020)

  • Kim Y-T, Lee H, Yoon H-O, Woo NC. Kinetics of dimethylated thioarsenicals and the formation of highly toxic dimethylmonothioarsinic acid in environment. Environmental Science and Technology. 50: 11637-11645 (2016)

    CAS  PubMed  Google Scholar 

  • Kollander B, Sand S, Almerud P, Ankarberg EH, Concha G, Barregård L, Darnerud P. Inorganic arsenic in food products on the Swedish market and a risk-based intake assessment. Science of The Total Environment. 672: 525-535 (2019)

    CAS  PubMed  Google Scholar 

  • KOSIS (Korean Statistical Information Service). Annual grain consumption per person in South Korea. Available from: http://kosis.kr/statHtml/statHtml.do?orgId=101&tblId=DT_1ED0001. Accessed Octobor 20, 2020

  • Lachenmeier DW, Rehm J. Comparative risk assessment of alcohol, tobacco, cannabis and other illicit drugs using the margin of exposure approach. Scientific Reports. 5: 1-7 (2015)

    Google Scholar 

  • Lee B-D, Eun J-B. Rice processing in food industry. Food Industry and Nutrition. 13: 1-8 (2008)

    CAS  Google Scholar 

  • Lee SG, Lee YS, Cho S-Y, Chung M-S, Cho M, Kang Y, Kim H, Kim D, Lee K-W. Monitoring of arsenic contents in domestic rice and human risk assessment for daily intake of inorganic arsenic in Korea. Journal of Food Composition and Analysis. 69: 25-32 (2018)

    CAS  Google Scholar 

  • Llorente-Mirandes T, Calderón J, Centrich F, Rubio R, López-Sánchez JF. A need for determination of arsenic species at low levels in cereal-based food and infant cereals. Validation of a method by IC–ICPMS. Food Chemistry. 147: 377-385 (2014)

    CAS  PubMed  Google Scholar 

  • Luvonga C, Rimmer CA, Yu LL, Lee SB. Organoarsenicals in seafood: occurrence, dietary exposure, toxicity, and risk assessment considerations–A review. Journal of Agricultural and Food Chemistry. 68: 943-960 (2020)

    CAS  PubMed  PubMed Central  Google Scholar 

  • Martorell I, Perelló G, Martí-Cid R, Llobet JM, Castell V, Domingo JL. Human exposure to arsenic, cadmium, mercury, and lead from foods in Catalonia, Spain: temporal trend. Biological Trace Element Research. 142: 309-322 (2011)

    CAS  PubMed  Google Scholar 

  • Mouritsen OG, Duelund L, Petersen MA, Hartmann AL, Frøst MB. Umami taste, free amino acid composition, and volatile compounds of brown seaweeds. Journal of Applied Phycology. 31: 1213-1232 (2019)

    CAS  Google Scholar 

  • Munera-Picazo S, Burló F, Carbonell-Barrachina ÁA. Arsenic speciation in rice-based food for adults with celiac disease. Food Additives and Contaminants: Part A. 31: 1358-1366 (2014)

    CAS  Google Scholar 

  • Norton GJ, Duan G, Dasgupta T, Islam MR, Lei M, Zhu Y, Deacon CM, Moran AC, Islam S, Zhao F-J. Environmental and genetic control of arsenic accumulation and speciation in rice grain: comparing a range of common cultivars grown in contaminated sites across Bangladesh, China, and India. Environmental Science and Technology. 43: 8381-8386 (2009)

    CAS  PubMed  Google Scholar 

  • Penrose W, Woolson E. Arsenic in the marine and aquatic environments: analysis, occurrence, and significance. Critical Reviews in Environmental Science and Technology. 4: 465-482 (1974)

    CAS  Google Scholar 

  • Rasheed H, Kay P, Slack R, Gong YY. Arsenic species in wheat, raw and cooked rice: Exposure and associated health implications. Science of the Total Environment. 634: 366-373 (2018)

    CAS  PubMed  Google Scholar 

  • Rintala E-M, Ekholm P, Koivisto P, Peltonen K, Venäläinen E-R. The intake of inorganic arsenic from long grain rice and rice-based baby food in Finland–low safety margin warrants follow up. Food Chemistry. 150: 199-205 (2014)

    CAS  PubMed  Google Scholar 

  • Rousseau M-C, Straif K, Siemiatycki J. IARC carcinogen update. Environmental Health Perspectives. 113: A580-A581 (2005)

    PubMed  PubMed Central  Google Scholar 

  • Sharafi K, Yunesian M, Nodehi RN, Mahvi AH, Pirsaheb M, Nazmara S. The reduction of toxic metals of various rice types by different preparation and cooking processes–Human health risk assessment in Tehran households, Iran. Food Chemistry. 280: 294-302 (2019)

    CAS  PubMed  Google Scholar 

  • Signes-Pastor AJ, Carey M, Meharg AA. Inorganic arsenic in rice-based products for infants and young children. Food Chemistry. 191: 128-134 (2016)

    CAS  PubMed  Google Scholar 

  • Styblo M, Del Razo LM, Vega L, Germolec DR, LeCluyse EL, Hamilton GA, Reed W, Wang C, Cullen WR, Thomas DJ. Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells. Archives of Toxicology. 74: 289-299 (2000)

    CAS  PubMed  Google Scholar 

  • Tak YJ, Lee JG, Yi YH, Kim YJ, Lee S, Cho BM, Cho YH. Association of handgrip strength with dietary intake in the Korean population: findings based on the Seventh Korea National Health and Nutrition Examination Survey (KNHANES VII-1), 2016. Nutrients. 10: 1180-1192 (2018)

    PubMed  PubMed Central  Google Scholar 

  • Vici G, Belli L, Biondi M, Polzonetti V. Gluten free diet and nutrient deficiencies: A review. Clinical Nutrition. 35: 1236-1241 (2016)

    CAS  PubMed  Google Scholar 

  • Wang Z, Xu J, Liu Y, Li Z, Xue Y, Wang Y, Xue C. Arsenic speciation of edible shrimp by high-performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC-ICP-MS): Method development and health assessment. Analytical Letters. 52: 2266-2282 (2019)

    CAS  Google Scholar 

  • WHO (World Health Organization). Safety evaluation of certain contaminants in food (2006)

  • Williams PN, Villada A, Deacon C, Raab A, Figuerola J, Green AJ, Feldmann J, Meharg AA. Greatly enhanced arsenic shoot assimilation in rice leads to elevated grain levels compared to wheat and barley. Environmental Science and Technology. 41: 6854-6859 (2007)

    CAS  PubMed  Google Scholar 

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Acknowledgements

This research was supported by a Grant (Grant No. 15162MFDS077) from the Ministry of Food and Drug Safety and a Korea University Grant (Grant No. K2207571). The authors thank the Institute of Biomedical Science & Food Safety, CJ-Korea University Food Safety Hall (Seoul, South Korea) for providing the equipment and facilities.

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Noh, CH., Chun, SH., Lim, J. et al. Monitoring arsenic species concentration in rice-based processed products distributed in South Korean markets and related risk assessment. Food Sci Biotechnol 32, 1361–1372 (2023). https://doi.org/10.1007/s10068-023-01270-9

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