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Prevalence of chondrocalcinosis in a Mexican tertiary care institution of musculoskeletal disorders

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Abstract

Introduction/objectives

The prevalence of chondrocalcinosis (CC) was reported as variable according to the geographic populations. However, there are no data regarding its prevalence in Mexico. Thus, we decided to investigate the Mexican prevalence of CC in a cohort of patients from a tertiary health care institution.

Methods

A retrospective analysis of radiographs of knees and wrists from our institution was performed. Inclusion criteria included patients > 50 years old having radiographs of knees and wrists. Radiographic presence of CC was classified according to a dichotomous evaluation assayed by two rheumatologists experts on the area.

Results

A total of 3.350 radiographs from 1.602 patients were evaluated. Forty-seven patients showed calcifications in at least one knee or wrist for an overall prevalence of 3%, of which 23.4% were men and 76.6% women. The knee was more commonly affected than the wrist (85.1% and 14.9% respectively). The prevalence according to gender was 2.9% in women, whereas, it was 3.2% in men. Only two patients (4.3%) showed a contemporaneous presence of CC in both hands and both knees. At knee level, the prevalence was 2.7%, whereas at the wrist, we reported a prevalence of 4.9%.

Conclusions

The prevalence of CC for Mexican population had not been reported so far. This a starting point to break the silence and encourage the knowledge of how this disease is associated with possible risk factors in Mexican population.

Key Points

•The prevalence of chondrocalcinosis in Mexico was 3%.

•The prevalence of knee chondrocalcinosis increases according to the age in women’s.

•The nixtamalized meals could be a protective factor for CC in Mexican population.

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Authors and Affiliations

  1. Division of Musculoskeletal and Rheumatic Disorders, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Calzada Mexico-Xochimilco 289 Colonia Arenal de Guadalupe, 14389, Mexico City, CP, Mexico

    Paloma De la Garza-Montaño, Carlos Pineda, Carlos Alberto Lozada-Pérez, Katia Camargo-Ibarias, María Fernanda González-Hernández, Gerardo A. Ruiz-De la Garza, Chiara Bertolazzi, Denise Clavijo-Cornejo & Marwin Gutierrez

  2. Division of Neurosciences, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico City, Mexico

    Alberto Avila-Luna

  3. Doctorado en Ciencias Biológicas y de la Salud, Universidad Autonoma Metropolitana, Iztapalapa, México City, Mexico

    Marwin Gutierrez

Authors
  1. Paloma De la Garza-Montaño
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  2. Carlos Pineda
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  3. Carlos Alberto Lozada-Pérez
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  4. Katia Camargo-Ibarias
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Contributions

PDLG-M and MG participated in designing the study, acquiring and interpreting the data, drafting of the manuscript, and giving final approval of the version of the paper to be published. CL, KC, and MF-H were involved in the selection of radiographs to be interpreted. Made substantial contributions to the manuscript preparation and were involved in revising the manuscript for important intellectual content. AA-L and GR-DLG were involved in the statistical analysis. CP and MG were involved in the lecture of radiographs. CB and DC-C participated in the review conception and gave substantial input to the data evaluation and manuscript preparation.

All authors read and approved the final version of the manuscript.

Corresponding author

Correspondence to Paloma De la Garza-Montaño.

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De la Garza-Montaño, P., Pineda, C., Lozada-Pérez, C.A. et al. Prevalence of chondrocalcinosis in a Mexican tertiary care institution of musculoskeletal disorders. Clin Rheumatol 38, 2595–2602 (2019). https://doi.org/10.1007/s10067-019-04614-1

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