Abstract
Purpose
Emergency groin hernia is an understudied research field despite its severity requiring emergency surgery associated with high postoperative morbidity and mortality rates. Therefore, this study aimed to investigate the characteristics of patients, hernias, and surgical repairs, as well as complication rates following emergency groin hernia repair.
Methods
Nationwide cohort study based on prospectively collected data obtained from the Danish Hernia Database and person-level linked to the Danish National Patient Registry. We included all adult patients undergoing an emergency groin hernia repair for inguinal- and/or femoral hernias registered in the Danish Hernia Database between January 1, 1998, and December 31, 2020. Primary outcomes were 30- and 90-day mortality, 30- and 90-day readmissions, and reoperations for recurrence. Outcomes were presented as crude numbers, odds ratios for mortality and readmission, and hazard ratios for reoperation.
Results
We included 9741 patients in the study. Within 30 days of surgery, 510 (6%) deaths and 1800 (23%) readmissions were recorded. During a median follow-up of 5 years, 537 (6%) reoperations for recurrence were performed. Multivariate analyses showed that mortality and readmission rates were influenced by increasing age, comorbidity, and bowel resection. Cumulative and adjusted reoperation rates were lower for mesh than non-mesh repairs. Moreover, mortality rates have improved over time, whereas readmission rates have increased over time.
Conclusions
Complication and mortality rates after emergency groin hernia repair remain high. This study underlines the importance of a timely repair in incarcerated hernias to avoid contaminated surgical fields and the need for bowel resection.
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References
Primatesta P, Goldacre MJ (1996) Inguinal hernia repair: incidence of elective and emergency surgery, readmission and mortality. Int J Epidemiol 25:835–839. https://doi.org/10.1093/ije/25.4.835
Nilsson H, Stylianidis G, Haapamäki M, Nilsson E, Nordin P (2007) Mortality after groin hernia surgery. Ann Surg 245:656–660. https://doi.org/10.1097/01.sla.0000251364.32698.4b
van den Heuvel B, Dwars B, Klassen D, Bonjer HJ (2011) Is surgical repair of an asymptomatic groin hernia appropriate? A review. Hernia 15:251–259. https://doi.org/10.1007/s10029-011-0796-y
INCA Trialists Collaboration (2011) Operation compared with watchful waiting in elderly male inguinal hernia patients: a review and data analysis. J Am Coll Surg 212(251–259):e1-4. https://doi.org/10.1016/j.jamcollsurg.2010.09.030
Dahlstrand U, Wollert S, Nordin P, Sandholm G, Gunnarsson U (2009) Emergency femoral hernia repair: a study based on a national register. Ann Surg 249:672–676. https://doi.org/10.1097/sla.0b013e31819ed943
Hernández-Irizarry R, Zendejas B, Ramirez T, Moreno M, Ali SM, Lohse CM, Farley DR (2012) Trends in emergent inguinal hernia surgery in Olmsted County, MN: a population-based study. Hernia 16:397–403. https://doi.org/10.1007/s10029-012-0926-1
Kurt N, Oncel M, Ozkan Z, Bingul S (2003) Risk and outcome of bowel resection in patients with incarcerated groin hernias: retrospective study. World J Surg 27:741–743. https://doi.org/10.1007/s00268-003-6826-x
Nilsson H, Nilsson E, Angerås U, Nordin P (2011) Mortality after groin hernia surgery: delay of treatment and cause of death. Hernia 15:301–307. https://doi.org/10.1007/s10029-011-0782-4
Köckerling F, Heine T, Adolf D, Zarras K, Weyhe D, Lammers B, Mayer F, Reinpold W, Jacob D (2021) Trends in emergent groin hernia repair—an analysis from the herniamed registry. Front Surg 8:655755. https://doi.org/10.3389/fsurg.2021.655755
HerniaSurge Group (2018) International guidelines for groin hernia management. Hernia 22:1–165. https://doi.org/10.1007/s10029-017-1668-x
Morley RL, Edmondson MJ, Rowlands C, Blazeby JM, Hinchliffe RJ (2018) Registration and publication of emergency and elective randomised controlled trials in surgery: a cohort study from trial registries. BMJ Open 8:e021700. https://doi.org/10.1136/bmjopen-2018-021700
Benchimol EI, Smeeth L, Guttmann A, Harron K, Moher D, Petersen I, Sørensen HT, von Elm E, Langan SM (2015) The REporting of studies conducted using observational routinely-collected health data (RECORD) Statement. PLoS Med 12:e1001885. https://doi.org/10.1371/journal.pmed.1001885
Friis-Andersen H, Bisgaard T (2016) The Danish inguinal hernia database. Clin Epidemiol 8:521–524. https://doi.org/10.2147/clep.s99512
Schmidt M, Schmidt SAJ, Sandegaard JL, Ehrenstein V, Pedersen L, Sørensen HT (2015) The Danish National patient registry: a review of content, data quality, and research potential. Clin Epidemiol 7:449–490. https://doi.org/10.2147/clep.s91125
Kyle-Leinhase I, Köckerling F, Jørgensen LN, Montgomery A, Gillion JF, Rodriguez JAP, Hope W, Muysoms F (2018) Comparison of hernia registries: the CORE project. Hernia 22:561–575. https://doi.org/10.1007/s10029-017-1724-6
Rosenberg J, Friis-Andersen H, Jørgensen LN, Andresen K (2021) Variables in the Danish hernia databases: inguinal and ventral. Laparosc Surg 5:30. https://doi.org/10.21037/ls-20-125
Pedersen CB (2011) The Danish civil registration system. Scand J Public Health 39:22–25. https://doi.org/10.1177/1403494810387965
Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383. https://doi.org/10.1016/0021-9681(87)90171-8
IBM SPSS Statistics for Windows [computer program]. Version 25.0.0.2. Armonk, NY: IBM Corp; 2017.
Suppiah A, Gatt M, Barandiaran J, Heng MS, Perry EP (2007) Outcomes of emergency and elective femoral hernia surgery in four district general hospitals: a 4-year study. Hernia 11:509–512. https://doi.org/10.1007/s10029-007-0262-z
Kjaergaard J, Bay-Nielsen M, Kehlet H (2010) Mortality following emergency groin hernia surgery in Denmark. Hernia 14:351–355. https://doi.org/10.1007/s10029-010-0657-0
East B, Pawlak M, deBeaux AC (2020) A manual reduction of hernia under analgesia/sedation (taxis) in the acute inguinal hernia: a useful technique in COVID-19 times to reduce the need for emergency surgery—a literature review. Hernia 24:937–941. https://doi.org/10.1007/s10029-020-02227-1
Ge BJ, Huang Q, Liu LM, Bian HP, Fan YZ (2010) Risk factors for bowel resection and outcome in patients with incarcerated groin hernias. Hernia 14:259–264. https://doi.org/10.1007/s10029-009-0602-2
Bay-Nielsen M, Kehlet H, Strand L, Malmstrøm J, Andersen FH, Wara P, Juul P, Callesen T (2001) Quality assessment of 26,304 herniorrhaphies in Denmark: a prospective nationwide study. Lancet 358:1124–1128. https://doi.org/10.1016/s0140-6736(01)06251-1
Acknowledgements
Ann Hou Sæter has received research funding from The Copenhagen Medical Society and the Research Council of Herlev and Gentofte Hospitals, which had no role in study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the article for publication.
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All the authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by AHS. The first draft of the manuscript was written by AHS, and all the authors commented on previous versions of the manuscript. All the authors read and approved the final manuscript.
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This study has received research funding from the Copenhagen Medical Society and the Research Council of Herlev and Gentofte Hospitals, which had no role in study design; in the collection, analysis, and interpretation of data; in the writing of the report; and in the decision to submit the article for publication.
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This study received approval from the Danish Data Protection Agency (journal no. P-2021-210). According to Danish law, ethical approval was not required.
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Sæter, A.H., Fonnes, S., Rosenberg, J. et al. High complication and mortality rates after emergency groin hernia repair: a nationwide register-based cohort study. Hernia 26, 1131–1141 (2022). https://doi.org/10.1007/s10029-022-02597-8
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DOI: https://doi.org/10.1007/s10029-022-02597-8