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Myeloid sarcoma on the temporal region before the onset of the acute myeloid leukemia: an extremely rare case report

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Oral and Maxillofacial Surgery Aims and scope Submit manuscript

Abstract

Purpose

Myeloid sarcoma (MS) is a rare malignant tumor that arises outside the bone marrow and usually occurs concomitantly or after the acute myeloid leukemia (AML). The aim of the present study is to report an extremely rare case of a patient with an MS arising in the maxillofacial region before the onset of AML to serve as a guide on how to conduct the initial assessment and diagnosis of similar cases.

Materials and methods

A 29-year-old healthy man complained of a “swelling on the head,” which was rapidly increasing. He was asymptomatic and never had a previous AML.

Results

The patient presented a large mass on the left temporal region. The computed tomography showed a well-delimited lesion extending from the lateral pterygoid muscle and involving the zygomatic arch and lateral orbital rim. The mass was diagnosed as an MS arising before the onset of the AML.

Conclusion

Masses of a rapid increase in the maxillofacial region should always raise suspicion of being an MS even in asymptomatic patients. Following a protocol of initial assessment and diagnosis will decrease the period between the initial appearance of the MS and effective treatment aimed to prevent or delay the manifestation of leukemia, improving the prognosis and survival of these patients.

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Acknowledgments

The case reported in this paper was diagnosed at the University Hospital of São Paulo University/Brazil. Thus, from the initial assessment to the referral of the patient, all credits are attributed to Dr. Marcia Maria de Gouveia and Dr. Aloísio Felipe-Silva.

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Authors and Affiliations

  1. Department of Oral & Maxillofacial Surgery, Traumatology and Prosthesis, Faculty of Dentistry, University of São Paulo, Av Prof. Lineu Prestes 2227 Butantã, São Paulo, State of São Paulo, 05508-000, Brazil

    Yuri Slusarenko da Silva & Maria da Graça Naclério-Homem

Authors
  1. Yuri Slusarenko da Silva
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  2. Maria da Graça Naclério-Homem
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Correspondence to Yuri Slusarenko da Silva.

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Slusarenko da Silva, Y., Naclério-Homem, M. Myeloid sarcoma on the temporal region before the onset of the acute myeloid leukemia: an extremely rare case report. Oral Maxillofac Surg 24, 251–254 (2020). https://doi.org/10.1007/s10006-020-00833-y

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  • DOI: https://doi.org/10.1007/s10006-020-00833-y

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