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Risk factors associated with the severity of pericoronitis of mandibular third molar

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Abstract

Purpose

The factors related to pericoronitis severity are unclear, and this study aimed to address this knowledge gap.

Materials and methods

In total, 113 patients with pericoronitis were included, and their demographic, clinical, and radiographic characteristics were recorded. The Patient–Clinician Pericoronitis Classification was used to score and categorize the severity of pericoronitis. Statistical analysis was conducted to examine the participants’ characteristics, validity of the Patient–Clinician Pericoronitis Classification, and risk factors associated with the severity of pericoronitis.

Results

The demographic, clinical, and radiographic characteristics of males and females were similar, except for Winter’s classification, pain, and intraoral swelling. The constructive validity of the Patient–Clinician Pericoronitis Classification was confirmed with three latent factors, including infection level, patient discomfort, and social interference. Ordinal logistic multivariate regression analysis revealed that upper respiratory tract infection was the sole risk factor associated with pericoronitis severity in males (odds ratio = 4.838). In females, pericoronitis on the right side (odds ratio = 2.486), distal radiolucency (odds ratio = 5.203), and menstruation (odds ratio = 3.416) were significant risk factors.

Conclusion

This study demonstrated the constructive validity of the Patient–Clinician Pericoronitis Classification. Among females, pericoronitis in mandibular third molars on the right side with radiolucency in menstruating individuals was more severe. In males, upper respiratory tract infection was the sole risk factor associated with pericoronitis severity.

Clinical relevance

Individuals with risk factors should be aware of severe pericoronitis in the coming future.

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Data availability

The datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request.

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Acknowledgements

The authors sincerely thank other members of the department of Oral Surgery, the participants who volunteered for the study.

Funding

This study did not receive any specific grants from funding agencies in the public, commercial, or not-for-profit sector.

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Authors and Affiliations

  1. Department of Oral Surgery, Faculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh City, 652 Nguyen Trai Street, Ward 11, District 5, Ho Chi Minh City, 72714, Vietnam

    Bao-Ngoc Thi Nguyen, Chi-Tam Nguyen-Le, Bich-Ly Thi Nguyen & Son Hoang Le

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  1. Bao-Ngoc Thi Nguyen
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  2. Chi-Tam Nguyen-Le
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  3. Bich-Ly Thi Nguyen
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  4. Son Hoang Le
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Contributions

Conceptualization: Bao-Ngoc Thi Nguyen, Chi-Tam Nguyen-Le, Bich-Ly Thi Nguyen, Son Hoang Le; Methodology: Bao-Ngoc Thi Nguyen, Bich-Ly Thi Nguyen, Son Hoang Le; Formal analysis and investigation: Bao-Ngoc Thi Nguyen, Chi-Tam Nguyen-Le, Son Hoang Le; Writing - original draft preparation: Bao-Ngoc Thi Nguyen, Chi-Tam Nguyen-Le, Bich-Ly Thi Nguyen, Son Hoang Le; Writing - review and editing: Bao-Ngoc Thi Nguyen, Chi-Tam Nguyen-Le, Bich-Ly Thi Nguyen, Son Hoang Le.

Corresponding author

Correspondence to Son Hoang Le.

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Ethical approval

This study was approved by the Medical Research Ethics Committee of the University of Medicine and Pharmacy at Ho Chi Minh City under No. 22491-ĐHYD (IRB-VN01002/IORG0008603/FWA00023448) on 20th October 2022.

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The authors have no conflicts of interest to declare that are relevant to the content of this article.

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Nguyen, BN.T., Nguyen-Le, CT., Nguyen, BL.T. et al. Risk factors associated with the severity of pericoronitis of mandibular third molar. Clin Oral Invest 28, 307 (2024). https://doi.org/10.1007/s00784-024-05714-2

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