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Evaluation of advanced platelet-rich fibrin compared to subepithelial connective tissue graft in the surgical management of interdental papilla recession: a randomized controlled trial

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Abstract

Objectives

The current study aims to compare advanced-platelet-rich fibrin membrane (A-PRF) to connective tissue graft (CTG) using Han and Takei’s approach.

Materials and methods

The defective papilla was randomly allocated to either the control group (CTG) or to the experimental group (A-PRF). Papilla height (PH) and percent change in the gingival black triangle (GBT) area were recorded at 1, 3, 6, 9, and 12 months.

Results

Thirty-two deficient IDPs with an initial papilla presence index (PPI) of 2 or 3 were included. At 12 months, the papilla-fill significantly increased in both groups (p < 0.001) without a significant difference between the study groups (p = 0.637). A mean gain in IDP height of 2.25 mm (± 0.97) in the CTG group and 1.86 mm (± 0.7) in the A-PRF group were recorded with a nonsignificant difference. Gingival black triangle fill showed a 57.98% fill in the CTG and 54.65% fill in the A-PRF group, with no statistically significant difference between the groups (0.956). Regarding postoperative pain patients, the CTG group consumed significantly more analgesics than the A-PRF group (11.75 ± 3.51 and 8 ± 3.08, respectively, with p = 0.003).

Conclusion

Both CTG and A-PRF were found to be equally effective in increasing deficient IDP height with Han and Takei’s surgical technique, with no significant difference. Within the current study’s limitations, A-PRF seems to be a viable alternative to CTG in the treatment of GBTs.

Clinical relevance

Multilayered A-PRF membrane can be used as a choice in the augmentation of receded papillae, using Han and Takei’s technique.

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Funding

The study was self-funded.

Author information

Authors and Affiliations

  1. Oral Medicine and Periodontology, Cairo University, Cairo, Egypt

    Sanabel O. Barakat, Omnia K. Tawfik, Samar El Kholy & Hani ElNahass

Authors
  1. Sanabel O. Barakat
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  2. Omnia K. Tawfik
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  3. Samar El Kholy
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  4. Hani ElNahass
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Contributions

SB conducted the surgical part, OK co-conceived the idea and reviewed the manuscript, SK supervised and analyzed the data, and HN co-conceived the idea and led the writing.

Corresponding author

Correspondence to Hani ElNahass.

Ethics declarations

Ethics approval and consent to participate

A written informed consent was obtained from each participant of the study.

The study was approved by the Ethical Committee of the Faculty of Dentistry, Cairo University, in February 2020 (12–2-20).

Competing interests

The authors declare no competing interests.

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Key findings

CTG and A-PRF were found to be equally effective in increasing deficient IDP height.

Supplementary Information

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Supplementary file1 (DOC 53 KB)

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Barakat, S.O., Tawfik, O.K., Kholy, S.E. et al. Evaluation of advanced platelet-rich fibrin compared to subepithelial connective tissue graft in the surgical management of interdental papilla recession: a randomized controlled trial. Clin Oral Invest 28, 87 (2024). https://doi.org/10.1007/s00784-023-05486-1

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