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Effect of double antibiotic and calcium hydroxide pastes on dislodgement resistance of an epoxy resin-based and two calcium silicate-based root canal sealers

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Abstract

Objectives

The purpose of the present study was to determine the dislodgement resistance of AH Plus, MTA Fillapex, and Total Fill BC sealer to root canal dentin walls following placement of calcium hydroxide (CH) or double antibiotic paste (DAP) medicaments.

Materials and methods

Root canals of 90 single-rooted human mandibular premolar teeth were instrumented with Reciproc rotary instruments to a size R50. The teeth were randomly divided into two experimental groups: those receiving an intracanal medicament with either CH or DAP and a control group (n = 30). After 3 weeks, the medicaments were removed by irrigation with 5 mL of 2.5 % NaOCl, 5 mL 17 % EDTA, and 5 mL distilled water under sonic agitation. Each group was then subdivided into three subgroups (n = 10), and the canals were filled with either AH Plus, MTA Fillapex, or Total Fill BC sealer. After 1 week, a push-out test was applied to the specimens and the results were analyzed using one-way analysis of variance (ANOVA) and post hoc Tamhane’s tests.

Results

Regardless of the type of intracanal medicament used, Total Fill BC Sealer and MTA Fillapex showed the highest and lowest bond strength, respectively (P < 0.05). The use or absence of medicaments did not significantly affect the dislodgment resistance of root canal fillings (P > 0.05). Prior CH placement improved dislodgement resistance of all sealers without statistical difference (P > 0.05). Adhesive failure between core and sealer was the most frequent failure mode.

Conclusions

Prior application of CH or DAP did not significantly affect the adhesion of the AH Plus, MTA Fillapex, and Total Fill BC Sealers.

Clinical relevance

There is a little information about the influence of antibiotic medicaments on the bond strength of root canal sealer. These findings suggest that the use of DAP does not affect the adhesion strength of AH Plus, MTA Fillapex, and Total Fill BC Sealers.

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References

  1. McGurkin-Smith R, Trope M, Caplan D, Sigurdsson A (2005) Reduction of intracanal bacteria using GT rotary instrumentation, 5.25% NaOCl, EDTA, and Ca(OH)2. J Endod 31:359–363

    Article  PubMed  Google Scholar 

  2. Siqueira JF Jr, Magalhaes KM, Rocas IN (2007c) Bacterial reduction in infected root canals treated with 2.5% NaOCl as an irrigant and calcium hydroxide/camphorated paramonochlorophenol paste as an intracanal dressing. J Endod 33:667–672

    Article  PubMed  Google Scholar 

  3. Siqueira JF Jr, Rocas IN, Paiva SS, Guimaraes-Pinto T, Magalhaes KM, Lima KC (2007a) Bacteriologic investigation of the effects of sodium hypochlorite and chlorhexidine during the endodontic treatment of teeth with apical periodontitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:122–130

    Article  PubMed  Google Scholar 

  4. Siqueira JF Jr, Paiva SS, Rocas IN (2007d) Reduction in the cultivable bacterial populations in infected root canals by a chlorhexidine-based antimicrobial protocol. J Endod 33:541–547

    Article  PubMed  Google Scholar 

  5. Siqueira JF Jr, Guimaraes-Pinto T, Rocas IN (2007b) Effects of chemomechanical preparation with 2.5% sodium hypochlorite and intracanal medication with calcium hydroxide on cultivable bacteria in infected root canals. J Endod 33:800–805

    Article  PubMed  Google Scholar 

  6. Miller EK, Lee JY, Tawil PZ, Teixeira FB, Vann WF Jr (2012) Emerging therapies for the management of traumatized immature permanent incisors. Pediatr Dent 34:66–69

    PubMed  Google Scholar 

  7. Mohammadi Z, Dummer PM (2011) Properties and applications of calcium hydroxide in endodontics and dental traumatology. Int Endod J 44:697–730

    Article  PubMed  Google Scholar 

  8. Kvist T, Molander A, Dahlen G, Reit C (2004) Microbiological evaluation of one- and two-visit endodontic treatment of teeth with apical periodontitis: a randomized, clinical trial. J Endod 30:572–576

    Article  PubMed  Google Scholar 

  9. Chavez De Paz LE, Dahlen G, Molander A, Moller A, Bergenholtz G (2003) Bacteria recovered from teeth with apical periodontitis after antimicrobial endodontic treatment. Int Endod J 36:500–508

    Article  PubMed  Google Scholar 

  10. Barbizam JV, Trope M, Teixeira EC, Tanomaru-Filho M, Teixeira FB (2008) Effect of calcium hydroxide intracanal dressing on the bond strength of a resin-based endodontic sealer. Braz Dent J 19:224–227

    Article  PubMed  Google Scholar 

  11. Ustun Y, Arslan S, Aslan T (2013) Effects of calcium hydroxide and propolis intracanal medicaments on bond strength of resin-based endodontic sealer as assessed by push-out test. Dent Mater J 32:913–919

    Article  PubMed  Google Scholar 

  12. Gomes-Filho JE, Duarte PC, de Oliveira CB, Watanabe S, Lodi CS, Cintra LT, Bernabe PF (2012) Tissue reaction to a triantibiotic paste used for endodontic tissue self-regeneration of nonvital immature permanent teeth. J Endod 38:91–94

    Article  PubMed  Google Scholar 

  13. Akcay M, Arslan H, Yasa B, Kavrik F, Yasa E (2014a) Spectrophotometric analysis of crown discoloration induced by various antibiotic pastes used in revascularization. J Endod 40:845–848

    Article  PubMed  Google Scholar 

  14. Hargreaves KM, Diogenes A, Teixeira FB (2013) Treatment options: biological basis of regenerative endodontic procedures. J Endod 39:30–43

    Article  Google Scholar 

  15. Arslan H, Akcay M, Capar ID, Ertas H, Ok E, Uysal B (2014b) Efficacy of needle irrigation, EndoActivator, and photon-initiated photoacoustic streaming technique on removal of double and triple antibiotic pastes. J Endod 40:1439–1442

    Article  PubMed  Google Scholar 

  16. Arslan H, Capar ID, Saygili G, Uysal B, Gok T, Ertas H, Topcuoglu HS (2014a) Efficacy of various irrigation protocols on the removal of triple antibiotic paste. Int Endod J 47:594–599

    Article  PubMed  Google Scholar 

  17. Chou K, George R, Walsh LJ (2014) Effectiveness of different intracanal irrigation techniques in removing intracanal paste medicaments. Aust Endod J 40:21–25

    Article  PubMed  Google Scholar 

  18. Berkhoff JA, Chen PB, Teixeira FB, Diogenes A (2014) Evaluation of triple antibiotic paste removal by different irrigation procedures. J Endod 40:1172–1177

    Article  PubMed  Google Scholar 

  19. Ruparel NB, Teixeira FB, Ferraz CC, Diogenes A (2012) Direct effect of intracanal medicaments on survival of stem cells of the apical papilla. J Endod 38:1372–1375

    Article  PubMed  Google Scholar 

  20. Labban N, Yassen GH, Windsor LJ, Platt JA (2014) The direct cytotoxic effects of medicaments used in endodontic regeneration on human dental pulp cells. Dent Traumatol 30:429–434

    Article  PubMed  Google Scholar 

  21. Guiotti FA, Kuga MC, Duarte MA, Sant’Anna AJ, Faria G (2014) Effect of calcium hydroxide dressing on push-out bond strength of endodontic sealers to root canal dentin. Braz Oral Res 28:1

    Article  Google Scholar 

  22. Amin SA, Seyam RS, El-Samman MA (2012) The effect of prior calcium hydroxide intracanal placement on the bond strength of two calcium silicate-based and an epoxy resin-based endodontic sealer. J Endod 38:696–699

    Article  PubMed  Google Scholar 

  23. Jainaen A, Palamara JE, Messer HH (2007) Push-out bond strengths of the dentine-sealer interface with and without a main cone. Int Endod J 40:882–890

    Article  PubMed  Google Scholar 

  24. Nagas E, Uyanik MO, Eymirli A, Cehreli ZC, Vallittu PK, Lassila LV, Durmaz V (2012) Dentin moisture conditions affect the adhesion of root canal sealers. J Endod 38:240–244

    Article  PubMed  Google Scholar 

  25. Total Fill (2015) http://www.fkg.ch/sites/default/files/fkg_totalfill_brochure_en.pdf. Accessed 8 July 2015

  26. Sagsen B, Ustun Y, Demirbuga S, Pala K (2011) Push-out bond strength of two new calcium silicate-based endodontic sealers to root canal dentine. Int Endod J 44:1088–1091

    Article  PubMed  Google Scholar 

  27. MTA Fillapex (2015) http://angelusdental.com/img/arquivos/mta_fillapex_technical_profile_download.pdf Accessed 8 July 2015

  28. da Silva JM, Silveira A, Santos E, Prado L, Pessoa OF (2011) Efficacy of sodium hypochlorite, ethylenediaminetetraacetic acid, citric acid and phosphoric acid in calcium hydroxide removal from the root canal: a microscopic cleanliness evaluation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 112:820–824

    Article  PubMed  Google Scholar 

  29. Rodig T, Vogel S, Zapf A, Hulsmann M (2010) Efficacy of different irrigants in the removal of calcium hydroxide from root canals. Int Endod J 43:519–527

    Article  PubMed  Google Scholar 

  30. Celik D, Er K, Serper A, Taşdemir T, Ceyhanlı KT (2014) Push-out bond strength of three calcium silicate cements to root canal dentine after two different irrigation regimes. Clin Oral Investig 18:1141–1146

    Article  PubMed  Google Scholar 

  31. Shipper G, Ørstavik D, Teixeira FB, Trope M (2004) An evaluation of microbial leakage in roots filled with thermoplastic synthetic polymer-based root canal filling material (Resilon). J Endod 30:342–347

    Article  PubMed  Google Scholar 

  32. Ulusoy OI, Genç O, Arslan S, Alaçam T, Gorgul G (2007) Fracture resistance of roots obturated with three different materials. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:705–708

    Article  PubMed  Google Scholar 

  33. Panitvisai P, Messer HH (1995) Cuspal deflection in molars in relation to endodontic and restorative procedures. J Endod 21:57–61

    Article  PubMed  Google Scholar 

  34. Huffman BP, Mai S, Pinna L, Weller RN, Primus CM, Gutmann JL, Pashley DH, Tay FR (2009) Dislocation resistance of ProRoot Endo Sealer, a calcium silicate-based root canal sealer, from radicular dentine. Int Endod J 42:34–46

    Article  PubMed  Google Scholar 

  35. Mjor IA, Smith MR, Ferrari M, Mannocci F (2001) The structure of dentine in the apical region of human teeth. Int Endod J 34:346–353

    Article  PubMed  Google Scholar 

  36. Akcay M, Arslan H, Topcuoglu HS, Tuncay O (2014b) Effect of calcium hydroxide and double and triple antibiotic pastes on the bond strength of epoxy resin-based sealer to root canal dentin. J Endod 40:1663–1667

    Article  PubMed  Google Scholar 

  37. Collares FM, Portella FF, Rodrigues SB, Celeste RK, Leitune VC, Samuel SM (2015) The influence of methodological variables on the push-out resistance to dislodgement of root filling materials: a meta-regression analysis. Int Endod J. doi:10.1111/iej.12539

    PubMed  Google Scholar 

  38. Shokouhinejad N, Gorjestani H, Nasseh AA, Hoseini A, Mohammadi M, Shamshiri AR (2013) Push-out bond strength of gutta-percha with a new bioceramic sealer in the presence or absence of smear layer. Aust Endod J 39:102–106

    Article  PubMed  Google Scholar 

  39. Carvalho CN, Bauer J, Ferrari PH, Souza SF, Soares SP, Loguercio AD, Bombana AC (2013) Influence of calcium hydroxide intracanal medication on bond strength of two endodontic resin-based sealers assessed by micropush-out test. Dent Traumatol 29:73–76

    Article  PubMed  Google Scholar 

  40. Felippe WT, Felippe MC, Rocha MJ (2006) The effect of mineral trioxide aggregate on the apexification and periapical healing of teeth with incomplete root formation. Int Endod J 39:2–9

    Article  PubMed  Google Scholar 

  41. Nagas E, Cehreli ZC, Uyanik MO, Vallittu PK, Lassila LV (2015) Effect of several intracanal medicaments on the push-out bond strength of ProRoot MTA and Biodentine. Int Endod J. doi:10.1111/iej.12433

    PubMed  Google Scholar 

  42. Topcuoglu HS, Arslan H, Akcay M, Saygili G, Cakici F, Topcuoglu G (2014) The effect of medicaments used in endodontic regeneration technique on the dislocation resistance of mineral trioxide aggregate to root canal dentin. J Endod 40:2041–2044

    Article  PubMed  Google Scholar 

  43. Nagas E, Cehreli Z, Uyanik MO, Durmaz V (2014) Bond strength of a calcium silicate-based sealer tested in bulk or with different main core materials. Braz Oral Res 28:1

    Article  Google Scholar 

  44. Williams C, Loushine RJ, Weller RN, Pashley DH, Tay FR (2006) A comparison of cohesive strength and stiffness of Resilon and gutta-percha. J Endod 32:553–555

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Endodontics, Faculty of Dentistry, Gaziosmanpaşa University, 60100, Tokat, Turkey

    Hakan Gokturk, Emre Bayram & Huda Melike Bayram

  2. Department of Restorative Dentistry and Endodontics, Faculty of Dentistry, Erciyes University, Kayseri, Turkey

    Tugrul Aslan & Yakup Ustun

Authors
  1. Hakan Gokturk
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  2. Emre Bayram
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  3. Huda Melike Bayram
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Correspondence to Hakan Gokturk.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Gokturk, H., Bayram, E., Bayram, H.M. et al. Effect of double antibiotic and calcium hydroxide pastes on dislodgement resistance of an epoxy resin-based and two calcium silicate-based root canal sealers. Clin Oral Invest 21, 1277–1282 (2017). https://doi.org/10.1007/s00784-016-1877-1

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  • DOI: https://doi.org/10.1007/s00784-016-1877-1

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