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Gender- and age-group-specific associations between physical performance and bone mineral density, falls, and osteoporotic fractures in Koreans: the Chungju Metabolic Disease Cohort study

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Abstract

Several factors increase the risk of fragility fracture, including low bone mineral density, falls, and poor physical performance. The associations among these factors have been investigated; however, most of the subjects of previous studies were either elderly men or elderly women, and the associations were controversial. The aim of this study was to evaluate the associations between physical performance and bone mineral density, and the history of falls and fractures, stratified by gender and age group. We analyzed 5368 subjects who were aged 50 years or older, including 1288 younger men (younger than 70 years), 1615 younger women (younger than 70 years), 1087 older men (70 years or older), and 1378 older women (70 years or older). We used the one-leg standing time (OLST) for assessing static balance and the timed up-and-go test (TUGT) for assessing dynamic balance. The subjects in the worst performance quartile for the OLST were more likely to have osteoporosis than those in the best performance quartile. Additionally, women who had experienced a fracture during the past 2 years were 1.68 times more likely to be in the worst performance quartile for the OLST than women without a previous fracture. Although the TUGT time was not associated with either the incidence of osteoporosis or the fracture history, the odds ratios for falling were 1.51 and 1.28 as the TUGT time increased by one standard deviation in younger men and younger women, respectively. The findings of the present study show that the OLST was associated with the incidence of osteoporosis and previous fracture and that the TUGT time was associated with the incidence of falling.

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Acknowledgments

This work was supported by a research grant from the Investigator-Initiated Studies Program of Merck & Co., Korea. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The authors thank all the survey personnel and the officers in Chungju Health Center for continued support.

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, 222 Banpo-daero Seocho-gu, Seoul, 137-701, South Korea

    Yejee Lim, Kyunghee Kim, Sun-Hee Ko, Kwanhoon Cho, Eun-Hee Jang, Seung-Hwan Lee, Dong Jun Lim, Ki Hyun Baek, Kun-Ho Yoon, Ho Young Son & Moo-Il Kang

  2. Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 137-701, South Korea

    Hee-Sung Ha, Hyeon-Woo Yim & Won-Chul Lee

  3. Clinical Research Coordinating Center, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 137-701, South Korea

    Mi Sun Park & Hyeon-Woo Yim

  4. Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul, 110-746, South Korea

    Ki Won Oh

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  1. Yejee Lim
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Correspondence to Moo-Il Kang.

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Lim, Y., Kim, K., Ko, SH. et al. Gender- and age-group-specific associations between physical performance and bone mineral density, falls, and osteoporotic fractures in Koreans: the Chungju Metabolic Disease Cohort study. J Bone Miner Metab 34, 336–346 (2016). https://doi.org/10.1007/s00774-015-0674-2

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