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AlCl3·6H2O-catalyzed Schiff-base reaction between aryl ketones and aromatic acylhydrazines/hydrazines in water

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Abstract

Schiff-bases have important applications in the field of analysis, biomedicine, as well as material sciences. Hydrazones and acylhydrazones are two representative types of Schiff-bases. In this study, a green synthesis of aromatic hydrazones and acylhydrazones via Schiff-base reaction of aryl ketones and aromatic acylhydrazines/hydrazines had been reported. In the synthesis, water was used as solvent and AlCl3·6H2O was used as catalyst. The reaction is simple, highly efficient, and eco-friendly.

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Acknowledgements

We thank for financial support given by Middle and Youth Teachers Scientific and Technological Talents Developing Fund (No. ZQ 2018-20), Natural Science Foundation of Shanghai (No. 15ZR1440400), Collaborative Innovation Fund (No. XTCX2016-14), National Youth Fund Project of China (No. 21602135), Shanghai Municipal Education Commission (Plateau Discipline Construction Program).

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Authors and Affiliations

  1. School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, 201418, China

    Zhi Xiang Zhao, Ting Li, Li Ping Cheng, Meng Li, Zhi Jian Zhong & Wan Pang

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  1. Zhi Xiang Zhao
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  2. Ting Li
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  3. Li Ping Cheng
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  4. Meng Li
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  5. Zhi Jian Zhong
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  6. Wan Pang
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Correspondence to Li Ping Cheng.

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Zhao, Z.X., Li, T., Cheng, L.P. et al. AlCl3·6H2O-catalyzed Schiff-base reaction between aryl ketones and aromatic acylhydrazines/hydrazines in water. Monatsh Chem 150, 1833–1839 (2019). https://doi.org/10.1007/s00706-019-02488-2

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  • DOI: https://doi.org/10.1007/s00706-019-02488-2

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