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Synthesis of spiro 2-(5-amino-2,3-dihydro-3-oxopyrrol-4-yl)-1,3-dialkylbenzimidazolium chlorides

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Abstract

The interaction of 1,3-dialkyl-2,3-dihydro-1H-benzo[d]imidazol-2-ylidenemethyl cyanides with N-trifluoroacylated acid chlorides gave the desired (3-cyano-2-oxo-3-hetarylpropyl)-2,2,2-trifluoroacetamides that upon detrifluoroacetylation provided the target 2-(5-amino-2,3-dihydro-3-oxopyrrol-4-yl)-1,3-dialkylbenzimidazolium chlorides.

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Acknowledgments

Alexey Dobrydnev acknowledges Patricia Dobrydneva for a fellowship and technical support.

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Authors and Affiliations

  1. Chemistry Department, Taras Shevchenko National University of Kiev, Vladimirskaya street 60, Kiev, 01601, Ukraine

    Alexey V. Dobrydnev, Yulian M. Volovenko, Alexandr V. Turov & Tatyana A. Volovnenko

  2. State Centre of Innovation Biotechnologies, Donetska Street 30, Kiev, 03151, Ukraine

    Alexey V. Dobrydnev

  3. Division of Functional Materials Chemistry, SSI “Institute for Single Crystals” National Academy of Science of Ukraine, Lenina avenue 60, Kharkiv, 61001, Ukraine

    Volodymyr V. Medviediev & Oleg V. Shishkin

  4. Department of Inorganic Chemistry, V. N. Karazin Kharkiv National University, Svobody square 4, Kharkiv, 61202, Ukraine

    Oleg V. Shishkin

Authors
  1. Alexey V. Dobrydnev
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  2. Yulian M. Volovenko
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  3. Alexandr V. Turov
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  4. Volodymyr V. Medviediev
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  5. Oleg V. Shishkin
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  6. Tatyana A. Volovnenko
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Corresponding author

Correspondence to Alexey V. Dobrydnev.

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Dobrydnev, A.V., Volovenko, Y.M., Turov, A.V. et al. Synthesis of spiro 2-(5-amino-2,3-dihydro-3-oxopyrrol-4-yl)-1,3-dialkylbenzimidazolium chlorides. Monatsh Chem 146, 931–939 (2015). https://doi.org/10.1007/s00706-015-1438-3

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  • DOI: https://doi.org/10.1007/s00706-015-1438-3

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