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Illness perceptions in pre-operative Parkinson’s disease patients

  • Neurology and Preclinical Neurological Studies - Original Article
  • Published:
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Abstract

Parkinson’s disease (PD) is a neurodegenerative disease, that combines motor and non-motor disorders, and alters patients’ autonomy. Even if subthalamic nucleus deep brain stimulation (STN-DBS) induces undisputable motor improvement, a post-operative social maladjustment was described by some patients. Our aim was to describe pre-operative illness perceptions in parkinsonian patients, and to determine the possible impact of cognitive restructuration over them. We analyzed 27 parkinsonian patient’s candidates to DBS. The mean age was 59 ± 5.94 years, and mean disease duration was 9.89 ± 4.15 years. The patients had two pre-operative psychological interviews (DBS-45 days, DBS-25 days) and completed the Illness Perception Questionnaire-Revised (IPQ-R) before the first interview and at DBS-1 day. The CRTG group (n = 13) had cognitive restructuration during second interview, on dysfunctional cognitions about their perception of post-DBS life which emerged from the first interview. The PIG group (n = 14) benefited of two non-structured interviews. No significant differences were found between the visits (DBS–45 days, DBS–1 day) for IPQ-R dimensions, except for the perception of “personal control” over PD which appears significantly higher for CRTG than PIG group (p = .039) at DBS-1 day, whereas the scores were quite similar at DBS-45 days. Illness perceptions seem to be stable over time and mostly influenced by disease experience of PD. However, the perception of personal control over PD seemed to be modulated through cognitive restructuration, giving patients’ control back over disease. Before DBS, illness perceptions investigation and restructuration constitute an interesting point to work on, to enhance perceived benefits of neurosurgery.

Trial registration: Clinical Research Program, N°IDRCB 2008-A00655-50, approved by the local ethics committee (CPP EST III, N° CPP: 08.07.03, first version date: 04/01/2008), registered on the ClinicalTrials.gov website (NCT02893449).

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Data Availability

The author confirms that all data generated or analysed during this study over illness perceptions are included in this published article.

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Acknowledgements

The authors thank PD patients for their motivated participation to the study.

Funding

This work was supported by the French Clinical Research Program under Grant (No. IDRCB 2008-A00655-50). Data are kept and available on demand to the CHRU de Nancy.

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Authors and Affiliations

  1. Service de Neurologie, Hôpital Central, CHRU Nancy, 29 avenue du Maréchal de Lattre de Tassigny, 54001, Nancy Cedex, France

    Mylène Meyer & Solène Frismand

  2. Département de Neurochirurgie, Hôpital Central, CHRU de Nancy, 29 avenue du Maréchal de Lattre de Tassigny, 54001, Nancy Cedex, France

    Sophie Colnat-Coulbois

  3. Université de Lorraine, 34 Cours Leopold, CS 25233, 54052, Nancy Cedex, France

    Sophie Colnat-Coulbois, Raymund Schwan & Elisabeth Spitz

  4. Service de Psychiatrie I, Hôpital Civil, 1 Place de l’hôpital, BP426, 67091, Strasbourg Cedex, France

    Pierre Vidailhet

  5. Service de Psychiatrie Adulte B, CHU Gabriel Montpied, 58 rue Montalembert, 63000, Clermont-Ferrand, France

    Pierre-Michel Llorca

  6. Centre Psychothérapique de Nancy, 1 rue du Docteur Archambault, BP 11010, 54521, Laxou Cedex, France

    Raymund Schwan

  7. Laboratoire de Psychologie de la Santé de Metz-EPSAM, Université de Lorraine, EA 4360 APEMAC, Ile du Saulcy, 57000, Metz, France

    Elisabeth Spitz

Authors
  1. Mylène Meyer
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  2. Sophie Colnat-Coulbois
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  3. Solène Frismand
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  4. Pierre Vidailhet
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  5. Pierre-Michel Llorca
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  6. Raymund Schwan
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  7. Elisabeth Spitz
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Contributions

RS, ES, and MM contributed to the conception and the design of the study, and to the material preparation. SC-C, SF, PV, P-ML, and MM contributed to the data collection. Data analysis and the first draft was made by MM and ES. All authors commented on previous versions of the article, and all authors read and approved the final manuscript.

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Correspondence to Mylène Meyer.

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Meyer, M., Colnat-Coulbois, S., Frismand, S. et al. Illness perceptions in pre-operative Parkinson’s disease patients. J Neural Transm 130, 647–654 (2023). https://doi.org/10.1007/s00702-023-02629-2

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  • DOI: https://doi.org/10.1007/s00702-023-02629-2

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