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Growth prediction in asymptomatic meningiomas: the utility of the AIMSS score

  • Original Article - Brain Tumors
  • Published:
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Abstract

Background

Management of asymptomatic meningiomas represents a challenge due to the absence of a solid consensus on which is the best management strategy. There are various known factors predicting meningiomas growth risk. However, the Asian Intracranial Meningioma Scoring System (AIMSS) is the only described score to quantify such risk thus emerging as a potential tool for management decisions. This study aims to validate this score on our series of asymptomatic meningiomas.

Method

We performed a retrospective review of asymptomatic meningiomas diagnosed at our institution between January 2008 and October 2016 and followed by an annual cerebral Magnetic Resonance Imaging (MRI). For each lesion, the AIMSS score was calculated thus classifying them in low (0–2), intermediate (3–6) or high risk (7–11) of rapid growth (>2cm3/year). We investigated the correlation between the expected Average Growth Rate (AGR) according to the score and the one obtained in our study. The mean growth velocity over the different risk groups was also compared.

Results

Overall, 69 asymptomatic meningiomas found incidentally in 46 patients were included in the study; 31 were assigned to the low-risk group, 34 to the intermediate-risk group and 4 to the high-risk group. Attending to the AGR, 0% showed rapid growth in the low-risk group, 12% in the intermediate-risk group, and 25% in the high-risk group. The mean growth velocity showed a significant difference over the different risk groups (p < 0,001).

Conclusions

According to our finding, the AIMSS score is a valid tool to estimate the risk of rapid growth of asymptomatic meningiomas. It is especially useful distinguishing between low- and intermediate-risk meningiomas. This feature would allow physicians to adjust the periodicity of radiological and clinical controls. Adding more known risk factors of rapid growth to the score might improve its predictive capabilities with the high-risk group.

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Authors and Affiliations

  1. Department of Neurological Surgery, Germans Trias i Pujol University Hospital, Ctra del Canyet sn, CP 08916, Barcelona, Spain

    Ferran Brugada-Bellsolà, Pilar Teixidor Rodríguez, Ana Rodríguez-Hernández, Roser Garcia-Armengol, Manel Tardáguila, Antonio González-Crespo, Carlos J. Domínguez & Jordi M. Rimbau

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  1. Ferran Brugada-Bellsolà
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  2. Pilar Teixidor Rodríguez
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  3. Ana Rodríguez-Hernández
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  4. Roser Garcia-Armengol
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  5. Manel Tardáguila
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  6. Antonio González-Crespo
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  7. Carlos J. Domínguez
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  8. Jordi M. Rimbau
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Correspondence to Ferran Brugada-Bellsolà.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (name of institute/committee) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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This article is part of the Topical Collection on Brain Tumors

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Brugada-Bellsolà, F., Teixidor Rodríguez, P., Rodríguez-Hernández, A. et al. Growth prediction in asymptomatic meningiomas: the utility of the AIMSS score. Acta Neurochir 161, 2233–2240 (2019). https://doi.org/10.1007/s00701-019-04056-3

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  • DOI: https://doi.org/10.1007/s00701-019-04056-3

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