Skip to main content

Advertisement

SpringerLink
Log in

Transient disappearance of microbleeds in the subacute period based on T2*-weighted gradient echo imaging in traumatic brain injury

  • Clinical Article - Brain Injury
  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Abstract

We report three cases of traumatic microbleeds evaluated by sequential observation. Hypo-intensities on T2* gradient echo imaging (T2*GEI) appeared just 2–3 h after the injury (the hyper-acute period). However, these hypo-intensities on T2*GEI disappeared or became obscure 2–6 days after the injury (the subacute period). A follow-up MRI again revealed clear hypo-intensities on T2*GEI 1–3 months after the injury (the chronic period). Our cases indicate that hypo-intensities on T2*GEI might change dynamically from the hyper-acute to the chronic period. The differences of susceptibility effects by hematoma age might be the cause of this dynamic change.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Adams JH, Doyle D, Ford I, Gennarelli TA, Graham DI, McLellan DR (1989) Diffuse axonal injury in head injury: definition, diagnosis and grading. Histopathology 15(1):49–59

    Article  CAS  PubMed  Google Scholar 

  2. Scheid R, Ott DV, Roth H, Schroeter ML, von Cramon DY (2007) Comparative magnetic resonance imaging at 1.5 and 3 Tesla for the evaluation of traumatic microbleeds. J Neurotrauma 24(12):1811–1820

    Article  PubMed  Google Scholar 

  3. Tong KA, Ashwal S, Holshouser BA, Nickerson JP, Wall CJ, Shutter LA, Osterdock RJ, Haacke EM, Kido D (2004) Diffuse axonal injury in children: clinical correlation with hemorrhagic lesions. Ann Neurol 56(1):36–50

    Article  PubMed  Google Scholar 

  4. Paterakis K, Karantanas AH, Komnos A, Volikas Z (2000) Outcome of patients with diffuse axonal injury: the significance and prognostic value of MRI in the acute phase. J Trauma 49(6):1071–1075

    Article  CAS  PubMed  Google Scholar 

  5. Scheid R, Walther K, Guthke T, Preul C, von Cramon DY (2006) Cognitive sequelae of diffuse axonal injury. Arch Neurol 63(3):418–424

    Article  PubMed  Google Scholar 

  6. Ezaki Y, Tsutsumi K, Morikawa M, Nagata I (2006) Lesions identified on T2*-weighted gradient echo images in two patients with suspected diffuse axonal injury that resolved in less than ten days. Acta Neurochir 148(5):547–550

    Article  CAS  PubMed  Google Scholar 

  7. Atlas SW, Thulborn KR (1998) MR detection of hyperacute parenchymal hemorrhage of the brain. AJNR Am J Neuroradiol 19:1471–1507

    CAS  PubMed  Google Scholar 

  8. Alemany Ripoll M, Gustafsson O, Síösteen B, Olsson Y, Raininko R (2002) MR follow-up of small experimental intracranial haemorrhages from hyperacute to subacute phase. Acta Radiol 43(1):2–9

    Article  PubMed  Google Scholar 

  9. Bradley WG Jr (1993) MR appearance of hemorrhage in the brain. Radiology 189(1):15–26

    Article  PubMed  Google Scholar 

  10. Hermier M, Nighoghossian N (2004) Contribution of susceptibility-weighted imaging to acute stroke assessment. Stroke 35:1989–1994

    Article  PubMed  Google Scholar 

  11. Linfante I, Llinas RH, Caplan LR, Warach S (1999) MRI features of intracerebral hemorrhage within 2 hours from symptom onset. Stroke 30:2263–2267

    Article  CAS  PubMed  Google Scholar 

  12. Tong KA, Ashwal S, Holshouser BA, Shutter LA, Herigault G, Haacke EM, Kido DK (2003) Hemorrhagic shearing lesions in children and adolescents with posttraumatic diffuse axonal injury: improved detection and initial results. Radiology 227(2):332–339

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurosurgery, Akita Red Cross Hospital, 222-1 Nawashirosawa, Saruta, Kamikitate, Akita, 010-1495, Japan

    Jun Watanabe, Jun Maruya & Keiichi Nishimaki

  2. Department of Neurosurgery, Nagano Red Cross Hospital, Nagano, Japan

    Yu Kanemaru

  3. Department of Radiology, Akita Red Cross Hospital, Akita, Japan

    Takaharu Miyauchi

Authors
  1. Jun Watanabe
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jun Maruya
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yu Kanemaru
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Takaharu Miyauchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Keiichi Nishimaki
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jun Watanabe.

Ethics declarations

Funding

No funding was received for this research.

Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed for the studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. “For this type of study, formal consent is not required.”

Informed consent

Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Watanabe, J., Maruya, J., Kanemaru, Y. et al. Transient disappearance of microbleeds in the subacute period based on T2*-weighted gradient echo imaging in traumatic brain injury. Acta Neurochir 158, 1247–1250 (2016). https://doi.org/10.1007/s00701-016-2805-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00701-016-2805-5

Keywords

Search

Navigation